Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Alison S Williams"'
Autor:
Joel A Mathews, Alison S Williams, Jeffrey D Brand, Allison P Wurmbrand, Lucas Chen, Fernanda Mc Ninin, Huiqing Si, David I Kasahara, Stephanie A Shore
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97707 (2014)
Ozone is an air pollutant that causes pulmonary symptoms. In mice, ozone exposure causes pulmonary injury and increases bronchoalveolar lavage macrophages and neutrophils. We have shown that IL-17A is important in the recruitment of neutrophils after
Externí odkaz:
https://doaj.org/article/012831df4c1b469a925ac43a62c47299
Autor:
David I Kasahara, Alison S Williams, Leandro A Benedito, Barbara Ranscht, Lester Kobzik, Christopher Hug, Stephanie A Shore
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65829 (2013)
Adiponectin, an adipose derived hormone with pleiotropic functions, binds to several proteins, including T-cadherin. We have previously reported that adiponectin deficient (Adipo(-/-)) mice have increased IL-17A-dependent neutrophil accumulation in t
Externí odkaz:
https://doaj.org/article/670afc39aa1445eeb8add390567d3314
Autor:
Alison S Williams, David I Kasahara, Norah G Verbout, Alexey V Fedulov, Ming Zhu, Huiqing Si, Allison P Wurmbrand, Christopher Hug, Barbara Ranscht, Stephanie A Shore
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41088 (2012)
Adiponectin is an adipose derived hormone that declines in obesity. We have previously shown that exogenous administration of adiponectin reduces allergic airways responses in mice. T-cadherin (T-cad; Cdh13) is a binding protein for the high molecula
Externí odkaz:
https://doaj.org/article/9f2430ecc1524d4bae9b339bbf49f753
Autor:
Frank Cuttitta, Allison P. Wurmbrand, Luiza Ribeiro, Stephanie A. Shore, Youngji Cho, David I. Kasahara, Joel A. Mathews, John N. Hutchinson, Jeffrey D. Brand, Mary E. Sunday, Nandini Krishnamoorthy, Bruce D. Levy, Alison S. Williams
Publikováno v:
American journal of respiratory cell and molecular biology. 58(3)
Ozone and obesity both increase IL-17A in the lungs. In mice, obesity augments the airway hyperresponsiveness and neutrophil recruitment induced by acute ozone exposure. Therefore, we examined the role of IL-17A in obesity-related increases in the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::256900f928c79d4f47a46c153c93c715
https://pubmed.ncbi.nlm.nih.gov/28957638
https://pubmed.ncbi.nlm.nih.gov/28957638
Autor:
Lucas Chen, Alison S. Williams, David I. Kasahara, Huiqing Si, Allison P. Wurmbrand, Stephanie A. Shore
Publikováno v:
Pulmonary Pharmacology & Therapeutics. 26:444-454
Obese mice exhibit innate airway hyperresponsiveness (AHR), a feature of asthma. Tumor necrosis factor alpha (TNFα) is implicated in the disease progression and chronic inflammatory status of both obesity and asthma. TNF acts via two TNF receptors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff4b7b8f170c9e2d420567878a2db67
https://doi.org/10.1016/j.pupt.2012.05.001
https://doi.org/10.1016/j.pupt.2012.05.001
Autor:
Joel A. Mathews, David I. Kasahara, Huiqing Si, Lucas Chen, Alison S. Williams, Allison P. Wurmbrand, Stephanie A. Shore
Publikováno v:
Environmental Health Perspectives
Background: Acute ozone (O3) exposure results in greater inflammation and airway hyperresponsiveness (AHR) in obese versus lean mice. Objectives: We examined the hypothesis that these augmented responses to O3 are the result of greater signaling thro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5be7514d8b1ae2aeabdeb4d04507ae71
https://doi.org/10.1289/ehp.1205880
https://doi.org/10.1289/ehp.1205880
Autor:
Razao Issa, Satyanarayana Medicherla, Ann M. Kapoun, Alison S. Williams, Sum-Yee Leung, Andrew L. Durham, Kian Fan Chung, Linda S. Higgins, Ian M. Adcock
Publikováno v:
European Journal of Pharmacology. 600:117-122
Ozone is a potent oxidant and causes airway hyperresponsiveness and neutrophilia. To determine the role of p38 mitogen-activated protein kinase (MAPK) activation, we studied the effect of a p38alpha inhibitor SD-282 (Scios Inc, Fremont, CA USA) on oz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7878ebe1cdc78c6e23337bd9280885da
https://doi.org/10.1016/j.ejphar.2008.09.031
https://doi.org/10.1016/j.ejphar.2008.09.031
Autor:
Joel A. Mathews, Allison P. Wurmbrand, Stephanie A. Shore, Lucas Chen, Alison S. Williams, David I. Kasahara
Innate airway hyperresponsiveness (AHR) and augmented responses to ozone, an asthma trigger, are characteristics of obese mice. Systemic inflammation, a condition of increased circulating concentrations of inflammatory moieties, occurs in obesity. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb13e4ed6573c87501100885a580e75
https://europepmc.org/articles/PMC4451401/
https://europepmc.org/articles/PMC4451401/
Autor:
Fernanda M. C. Ninin, Lucas Chen, Alison S. Williams, Joel A. Mathews, David I. Kasahara, Jeffrey D. Brand, Huiqing Si, Allison P. Wurmbrand, Stephanie A. Shore
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97707 (2014)
PLoS ONE
PLoS ONE
Ozone is an air pollutant that causes pulmonary symptoms. In mice, ozone exposure causes pulmonary injury and increases bronchoalveolar lavage macrophages and neutrophils. We have shown that IL-17A is important in the recruitment of neutrophils after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e41f8ba834cda94f2dd6fb0602a74f4
http://europepmc.org/articles/PMC4019643?pdf=render
http://europepmc.org/articles/PMC4019643?pdf=render
Autor:
Felippe Lazar Neto, Fernanda M. C. Ninin, Alison S. Williams, Joel A. Mathews, Norah G. Verbout, Allison P. Wurmbrand, David I. Kasahara, Stephanie A. Shore, Leandro A.P. Benedito, Hye Young Kim, Dale T. Umetsu, Christopher Hug
Adiponectin is an adipose-derived hormone with anti-inflammatory activity. Following subacute ozone exposure (0.3 ppm for 24–72 h), neutrophilic inflammation and IL-6 are augmented in adiponectin-deficient ( Adipo−/−) mice. The IL-17/granulocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b630cab46bcf61a597befa90e9796a
https://europepmc.org/articles/PMC3949085/
https://europepmc.org/articles/PMC3949085/