Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alison R Hill"'
Autor:
Annieck M. Diks, Hans de Graaf, Cristina Teodosio, Rick J. Groenland, Bas de Mooij, Muktar Ibrahim, Alison R. Hill, Robert C. Read, Jacques J.M. van Dongen, Magdalena A. Berkowska, on behalf of the IMI-2 PERISCOPE Consortium
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 5 (2023)
BACKGROUND To date, only limited data are available on the mechanisms of protection against colonization with Bordetella pertussis in humans.METHODS In this study, the cellular responses to B. pertussis challenge were monitored longitudinally using h
Externí odkaz:
https://doaj.org/article/580ba9981ff247b7ae674ff31d83cabc
Autor:
Adam P Dale, Anastasia A Theodosiou, Diane F Gbesemete, Jonathan M Guy, Eleanor F Jones, Alison R Hill, Muktar M Ibrahim, Hans de Graaf, Muhammad Ahmed, Saul N Faust, Andrew R Gorringe, Marta E Polak, Jay R Laver, Robert C Read
Publikováno v:
The Lancet Microbe. 3:e931-e943
Pharyngeal colonisation by the commensal bacterium Neisseria lactamica inhibits colonisation by Neisseria meningitidis and has an inverse epidemiological association with meningococcal disease. The mechanisms that underpin this relationship are uncle
Autor:
Muhammad Ahmed, Holly E. Humphries, Jonathan M. Guy, Martin C. J. Maiden, Adam P. Dale, David W. Cleary, Hans de Graaf, Andrew Gorringe, Zoe C. Pounce, Carl N. Webb, Lauren Allen, Saul N. Faust, Konstantinos Belogiannis, Robert C. Read, Alison R Hill, Graham Berreen, Jay R. Laver, Eleanor F. Roche, Muktar Ibrahim, Anish K. Pandey, Diane Gbesemete
The human nasopharynx contains a stable microbial ecosystem of commensal and potentially pathogenic bacteria, which can elicit protective primary and secondary immune responses. Experimental intranasal infection of human adults with the commensal Nei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246da752c1e26ea390565563b94a9080
https://eprints.soton.ac.uk/450488/
https://eprints.soton.ac.uk/450488/
Autor:
Robert C. Read, Alison R Hill, Andrew T M Vaughan, Diane Gbesemete, Muktar Ibrahim, Guy A. M. Berbers, Hans de Graaf, Anne-Marie Buisman, Andrew Gorringe, Kent E. Kester, Dimitri A. Diavatopoulos, Saul N. Faust, Andrew Preston
Publikováno v:
Clinical Infectious Diseases, 71, 2, pp. 403-411
Clinical Infectious Diseases
Clin Infect Dis
Clinical Infectious Diseases, 71, 403-411
Clinical Infectious Diseases
Clin Infect Dis
Clinical Infectious Diseases, 71, 403-411
Background Bordetella pertussis is among the leading causes of vaccine-preventable deaths and morbidity globally. Human asymptomatic carriage as a reservoir for community transmission of infections might be a target of future vaccine strategies, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::505247258302b4dec841398f7d25f7b0
https://hdl.handle.net/2066/225112
https://hdl.handle.net/2066/225112
Autor:
Peter Glynne-Jones, Martin C. Grossel, Martyn Hill, Alison R Hill, Emily J. Swindle, Cornelia Blume, Björn Hammarström, David E. Smart, Donna E. Davies, Adam L. Fisher, Angela Tait
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Engineering tissue structures that mimic those found in vivo remains a challenge for modern biology. We demonstrate a new technique for engineering composite structures of cells comprising layers of heterogeneous cell types. An acoustofluidic bioreac
Autor:
Adam P Dale, Anastasia A Theodosiou, Jay R Laver, Eleanor F Roche, Alison R Hill, Andrew Gorringe, Marta E Polak, Andrew T Vaughan, Robert C Read
Publikováno v:
The Journal of Immunology. 204:231.21-231.21
Neisseria lactamica (Nlac) is a commensal of the human oropharynx. Colonisation with Nlac significantly reduces colonisation by N. meningitidis (Nmen). We hypothesised that cross-reactive adaptive cellular immune responses were responsible for this e
Publikováno v:
Airway Cell Biology and Immunopathology.
Autor:
Myron Christodoulides, Charlene Akoto, Miao-Chiu Hung, Renee J. Phillips, Wei-Ming Tan, Maria Victoria Humbert, John E. Heckels, Alison R Hill
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0160403 (2016)
PLoS ONE, Vol 11, Iss 8, p e0160403 (2016)
The cbf gene from Neisseria meningitidis strain MC58 encoding the putative Cell Binding Factor (CBF, NMB0345/NEIS1825) protein was cloned into the pRSETA system and a ~36-kDa recombinant (r)CBF protein expressed in Escherichia coli and purified by me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47b26861fc64b1eee6bb747bd0831ae
https://eprints.soton.ac.uk/399262/
https://eprints.soton.ac.uk/399262/
Autor:
Patrick Dennison, Matthew J. Edwards, Peter H. Howarth, Emily J. Swindle, Cornelia Blume, Hitasha Rupani, Kamran Tariq, Alison R Hill, Jessica Donaldson, Donna E. Davies, Liku B. Tezera, Natalie P. Smithers, Christopher Grainge
Publikováno v:
Tissue Barriers
The bronchial epithelium and underlying fibroblasts form an epithelial mesenchymal trophic unit (EMTU) which controls the airway microenvironment. We hypothesised that cell-cell communication within the EMTU propagates and amplifies the innate immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737dd48199b7fc15739484a618aeaa9a
https://eprints.soton.ac.uk/398588/
https://eprints.soton.ac.uk/398588/
Autor:
Robert C. Read, Alison R Hill, Dimitri A. Diavatopoulos, Diane Gbesemete, Kent E. Kester, Saul N. Faust, Muktar Ibrahim, Hans de Graaf, Guy A. M. Berbers, Andrew Gorringe
Publikováno v:
Open Forum Infectious Diseases
Background Bordetella pertussis is one of the leading causes of vaccine preventable death and morbidity globally. Over the last 20 years, pertussis has resurged worldwide, even in territories with high immunization coverage. To improve vaccine strate