Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Alison N Thorburn"'
Autor:
Alison N Thorburn, Hsin-Yi Tseng, Chantal Donovan, Nicole G Hansbro, Andrew G Jarnicki, Paul S Foster, Peter G Gibson, Philip M Hansbro
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156402 (2016)
BACKGROUND:Exposure to non-pathogenic Streptococcus pneumoniae and vaccination are inversely associated with asthma. Studies in animal models demonstrate that airway administration of S. pneumoniae (live or killed), or its vaccines or components, sup
Externí odkaz:
https://doaj.org/article/9082f3d2b79d4844b7c1b01afcf1a77c
Autor:
Robert Brink, Charles R. Mackay, Di Yu, Jian Tan, Louis M. Tsai, Katherine Bourne, Alison N. Thorburn, Remy Robert, Linda J. Mason, Nina Chevalier, Connie H.Y. Wong, Laurence Macia
Publikováno v:
Arthritis & Rheumatology. 68:1026-1038
ObjectiveAntibody-mediated autoimmunity involves cognate interactions between self-reactive T cells and B cells during germinal center (GC) reactions. The aim of this study was to determine the role of essential follicular helper T (Tfh) cell molecul
Autor:
Natalie Lister, Maree V. Hammett, J. Homann, M A Malin, Daniel S. Layton, Jessica Kate Morison, Alison N. Thorburn, Richard L. Boyd, Ann P. Chidgey, Tracy Heng
Publikováno v:
American Journal of Transplantation. 14:2478-2490
Mixed hematopoietic chimerism is a powerful means of generating donor-specific tolerance, allowing long-term graft acceptance without lifelong dependence on immunosuppressive drugs. To avoid the need for whole body irradiation and associated side eff
Autor:
Paul S. Foster, Andrew G. Jarnicki, Peter G. Gibson, Hsin-Yi Tseng, Chantal Donovan, Philip M. Hansbro, Nicole G. Hansbro, Alison N. Thorburn
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 6, p e0156402 (2016)
PLoS ONE, Vol 11, Iss 6, p e0156402 (2016)
© 2016 Thorburn et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa61736c5ea4022d4120de12ad97a713
https://hdl.handle.net/10453/128822
https://hdl.handle.net/10453/128822
Autor:
Charles R. Mackay, Connie H.Y. Wong, Laurence Macia, Craig I. McKenzie, Alison N. Thorburn, Brendan E. Russ, Jian Tan, Seth L. Masters, Linda J. Mason, Florence Lim, Remy Robert, Nina Chevalier
Publikováno v:
Journal of autoimmunity. 73
Environmental factors contribute to development of autoimmune diseases. For instance, human autoimmune arthritis can associate with intestinal inflammation, cigarette smoking, periodontal disease, and various infections. The cellular and, molecular p
Publikováno v:
The Journal of Immunology. 188:4611-4620
Asthma is an allergic airways disease (AAD) caused by dysregulated immune responses and characterized by eosinophilic inflammation, mucus hypersecretion, and airway hyperresponsiveness (AHR). NKT cells have been shown to contribute to AHR in some mou
Autor:
Eliana Mariño, Lauren C. Binge, Charles R. Mackay, Kendle M. Maslowski, Kate E. Rogers, Jan Kranich, Angélica T. Vieira, Laurence Macia, Alison N. Thorburn
Publikováno v:
Immunological Reviews. 245:164-176
Certain autoimmune diseases as well as asthma have increased in recent decades, particularly in developed countries. The hygiene hypothesis has been the prevailing model to account for this increase; however, epidemiology studies also support the con
Publikováno v:
Expert Opinion on Biological Therapy. 9:621-629
Asthma is a common global health problem. Environmental exposures such as bacteria may protect against asthma development.This review aims to examine the possible protective role of pneumococcal infection and vaccination in asthma.A review of known e
Autor:
Katie Leach, Nina Chevalier, Robert J. Moore, Suzanne Luong, Caroline Ang, Jian Tan, Charles R. Mackay, Atsushi Hijikata, Mikako Maruya, Lauren C. Binge, Richard A. Flavell, Dragana Stanley, Alison N. Thorburn, Craig R. M. McKenzie, Angélica T. Vieira, Sidonia Fagarasan, Laurence Macia, Connie H.Y. Wong, Mauro M. Teixeira, Stefan Offermanns, Eliana Mariño, Remy Robert
Publikováno v:
Nature Communications. 6
Diet and the gut microbiota may underpin numerous human diseases. A major metabolic product of commensal bacteria are short-chain fatty acids (SCFAs) that derive from fermentation of dietary fibre. Here we show that diets deficient or low in fibre ex
Autor:
Dragana Stanley, Robert J. Moore, Lee H. Wong, Laurence Macia, Raymond Shim, Charles R. Mackay, Lisa Wood, Dedreia Tull, Remy Robert, Connie H.Y. Wong, Eliana Mariño, Vanessa E. Murphy, Laura K Roberts, Sj Shen, Jian Tan, Linda J. Mason, Nina Chevalier, Peter G. Gibson, Alison N. Thorburn, Craig R. M. McKenzie, Joerg Mattes, Malcolm J. McConville
Publikováno v:
Nature communications. 6
Asthma is prevalent in Western countries, and recent explanations have evoked the actions of the gut microbiota. Here we show that feeding mice a high-fibre diet yields a distinctive gut microbiota, which increases the levels of the short-chain fatty