Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Alison Motsinger‐Reif"'
Autor:
Jennifer Johnston, Julie Sapp, Seeley Yoo, Zara Wermers, Sophia Hernandez, Alison Motsinger-Reif, Adam Burkholder, David Fargo, Janet Hall, Leslie Biesecker
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101374- (2024)
Externí odkaz:
https://doaj.org/article/17d531c02cbf4de4a90b334048975522
Autor:
Nicole D. Armstrong, Vinodh Srinivasasainagendra, Farah Ammous, Themistocles L. Assimes, Amber L. Beitelshees, Jennifer Brody, Brian E. Cade, Yii-Der Ida Chen, Han Chen, Paul S. de Vries, James S. Floyd, Nora Franceschini, Xiuqing Guo, Jacklyn N. Hellwege, John S. House, Chii-Min Hwu, Sharon L. R. Kardia, Ethan M. Lange, Leslie A. Lange, Caitrin W. McDonough, May E. Montasser, Jeffrey R. O’Connell, Megan M. Shuey, Xiao Sun, Rikki M. Tanner, Zhe Wang, Wei Zhao, April P. Carson, Todd L. Edwards, Tanika N. Kelly, Eimear E. Kenny, Charles Kooperberg, Ruth J. F. Loos, Alanna C. Morrison, Alison Motsinger-Reif, Bruce M. Psaty, Dabeeru C. Rao, Susan Redline, Stephen S. Rich, Jerome I. Rotter, Jennifer A. Smith, Albert V. Smith, Marguerite R. Irvin, Donna K. Arnett
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: Apparent treatment-resistant hypertension (aTRH) is characterized by the use of four or more antihypertensive (AHT) classes to achieve blood pressure (BP) control. In the current study, we conducted single-variant and gene-based analyse
Externí odkaz:
https://doaj.org/article/7b206fd782484f169fb7415ed4c3d533
Autor:
Dereje D. Jima, David A. Skaar, Antonio Planchart, Alison Motsinger-Reif, Sebnem E. Cevik, Sarah S. Park, Michael Cowley, Fred Wright, John House, Andy Liu, Randy L. Jirtle, Cathrine Hoyo
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 1920-1943 (2022)
Imprinted genes – critical for growth, metabolism, and neuronal function – are expressed from one parental allele. Parent-of-origin-dependent CpG methylation regulates this expression at imprint control regions (ICRs). Since ICRs are established
Externí odkaz:
https://doaj.org/article/7839a357ee7a4b1cb5f201df811ebdaf
Autor:
Jun Ma, Alison Motsinger-Reif
Publikováno v:
BioData Mining, Vol 14, Iss 1, Pp 1-15 (2021)
Abstract Background Cancer is one of the main causes of death worldwide. Combination drug therapy has been a mainstay of cancer treatment for decades and has been shown to reduce host toxicity and prevent the development of acquired drug resistance.
Externí odkaz:
https://doaj.org/article/de5e21b8d38743d6808049936a3f24b0
Autor:
Meisha Mandal, Josh Levy, Cataia Ives, Stephen Hwang, Yi-Hui Zhou, Alison Motsinger-Reif, Huaqin Pan, Wayne Huggins, Carol Hamilton, Fred Wright, Stephen Edwards
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The need to test chemicals in a timely and cost-effective manner has driven the development of new alternative methods (NAMs) that utilize in silico and in vitro approaches for toxicity prediction. There is a wealth of existing data from human studie
Externí odkaz:
https://doaj.org/article/cc487cb0c7fe4ac690263eae01f8df22
Autor:
Andrew M. Lewis, Rachael Thomas, Matthew Breen, Keith Peden, Belete Teferedegne, Gideon Foseh, Alison Motsinger-Reif, Daniel Rotroff, Gladys Lewis
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
To study neoplasia in tissue culture, cell lines representing the evolution of normal cells to tumor cells are needed. To produce such cells, we developed the AGMK1-9T7 cell line, established cell banks at 10-passage intervals, and characterized thei
Externí odkaz:
https://doaj.org/article/efdc58021a3b4c2bbf6007c60aa81177
Autor:
Kaitlyn Craun, Joanne Ekena, James Sacco, Tao Jiang, Alison Motsinger‐Reif, Lauren A. Trepanier
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 5, Pp 2068-2077 (2020)
Abstract Background Non‐Hodgkin lymphoma in humans is associated with environmental chemical exposures, and risk is enhanced by genetic variants in glutathione S‐transferases (GST) enzymes. Objective We hypothesized that boxer dogs, a breed at ri
Externí odkaz:
https://doaj.org/article/b52c5f1dedcb421294b1f1d546fb7cd3
Publikováno v:
Journal of Cheminformatics, Vol 11, Iss 1, Pp 1-15 (2019)
Abstract Developing predictive and transparent approaches to the analysis of metabolite profiles across patient cohorts is of critical importance for understanding the events that trigger or modulate traits of interest (e.g., disease progression, dru
Externí odkaz:
https://doaj.org/article/3fcbdd04a8424ab6af26fce3b182331d
Publikováno v:
Dose-Response, Vol 18 (2020)
Nonlinear dose–response relationships exist extensively in the cellular, biochemical, and physiologic processes that are affected by varying levels of biological, chemical, or radiation stress. Modeling such responses is a crucial component of toxi
Externí odkaz:
https://doaj.org/article/990d4901e9694c27834cbeb127a82201
Publikováno v:
BioData Mining, Vol 11, Iss 1, Pp 1-19 (2018)
Abstract Background Gene set analysis is a valuable tool to summarize high-dimensional gene expression data in terms of biologically relevant sets. This is an active area of research and numerous gene set analysis methods have been developed. Despite
Externí odkaz:
https://doaj.org/article/bd6680547fec402d8eb2d4ccbc856f8d