Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Alison Mercer-Smith"'
Autor:
Hunter N. Bomba, Abigail Carey‐Ewend, Kevin T. Sheets, Alain Valdivia, Morgan Goetz, Ingrid A. Findlay, Alison Mercer‐Smith, Lauren E. Kass, Simon Khagi, Shawn D. Hingtgen
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 2, Pp n/a-n/a (2022)
Abstract Induced neural stem cells (iNSCs) have emerged as a promising therapeutic platform for glioblastoma (GBM). iNSCs have the innate ability to home to tumor foci, making them ideal carriers for antitumor payloads. However, the in vivo persisten
Externí odkaz:
https://doaj.org/article/c2b623cb992f42d297503de74ed1aa7c
Publikováno v:
Neuro-Oncology Advances. 5
Glioblastoma (GBM) is the most prevalent, aggressive, primary brain cancer in adults and continues to pose major medical challenges due in part to its high rate of recurrence. Extensive research is underway to discover new therapies that target GBM c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::480d90dfeb1663d50f82fd8ad3f46c22
https://doi.org/10.1093/noajnl/vdad047
https://doi.org/10.1093/noajnl/vdad047
Autor:
Hunter Bomba, Lauren Kass, Abigail Carey-Ewend, Kevin Sheets, Alain Valdivia, Morgan Goetz, Ingrid Findlay, Alison Mercer-Smith, Simon Khagi, Shawn Hingtgen
Publikováno v:
Neuro-Oncology. 24:vii94-vii95
Therapeutic neural stem cells (tNSCs) are a promising new platform for the treatment of glioblastoma (GBM). tNSCs exhibit a characteristic known as tumor tropism, in which they can migrate towards distant GBM foci via cytokine signaling. Complementar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23342f29da5a0388a6f42114460ee8d6
https://doi.org/10.1093/neuonc/noac209.350
https://doi.org/10.1093/neuonc/noac209.350
Autor:
null Hunter N. Bomba, null Abigail Carey‐Ewend, null Kevin T. Sheets, null Alain Valdivia, null Morgan Goetz, null Ingrid A. Findlay, null Alison Mercer‐Smith, null Lauren E. Kass, null Simon Khagi, null Shawn D. Hingtgen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9e7411644898fa79ad64c48b76c39c1
https://doi.org/10.1002/btm2.10283/v2/response1
https://doi.org/10.1002/btm2.10283/v2/response1
Autor:
Hunter N. Bomba, Abigail Carey‐Ewend, Kevin T. Sheets, Alain Valdivia, Morgan Goetz, Ingrid A. Findlay, Alison Mercer‐Smith, Lauren E. Kass, Simon Khagi, Shawn D. Hingtgen
Publikováno v:
Bioengineeringtranslational medicine. 7(2)
Induced neural stem cells (iNSCs) have emerged as a promising therapeutic platform for glioblastoma (GBM). iNSCs have the innate ability to home to tumor foci, making them ideal carriers for antitumor payloads. However, the in vivo persistence of iNS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21c92d4c9f593a564e143d33445598c
https://pubmed.ncbi.nlm.nih.gov/35600639
https://pubmed.ncbi.nlm.nih.gov/35600639
Publikováno v:
Stem Cell Rev Rep
Despite the recent influx of immunotherapies and small molecule drugs to treat tumors, cancer remains a leading cause of death in the United States, in large part due to the difficulties of treating metastatic cancer. Stem cells, which are inherently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf3b5a71642c605ba3766d451cbb574
https://europepmc.org/articles/PMC8602714/
https://europepmc.org/articles/PMC8602714/
Autor:
Carey K. Anders, Shawn Hingtgen, Alison Mercer-Smith, Andrew Buckley, Li Qian, Alain Valdivia, Yuchen Yang, Alex S. Woodell, Juli R. Bagó, Wulin Jiang, Michael H. Marand
Publikováno v:
Science Advances
Enhanced induced neural stem cell therapy shows superior efficacy in treating triple-negative breast cancer brain metastases.
Engineered tumor-homing neural stem cells (NSCs) have shown promise in treating cancer. Recently, we transdifferentiate
Engineered tumor-homing neural stem cells (NSCs) have shown promise in treating cancer. Recently, we transdifferentiate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48fe2ecc1a6781ce530eb0a7bcaf18d8
https://doi.org/10.1126/sciadv.abf1526
https://doi.org/10.1126/sciadv.abf1526
Autor:
Alison Mercer-Smith, Wulin Jiang, Alain Valdivia, Noah Bell, Alex Woodell, Scott Floyd, Shawn Hingtgen
Publikováno v:
Neuro-Oncology Advances. 4:i15-i15
INTRODUCTION Non-small cell lung cancer (NSCLC) is the most common cancer to spread to the brain, and spread to the leptomeninges is particularly devastating, with a median survival of only months. While radiation may offer symptomatic relief, new ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74d4ae3d02af2433b23facf9aefc7f15
https://doi.org/10.1093/noajnl/vdac078.060
https://doi.org/10.1093/noajnl/vdac078.060
Autor:
Carey K. Anders, Kevin Sheets, Alison Mercer-Smith, Alain Valdivia, Alex S. Woodell, Juli R. Bagó, Wulin Jiang, Stephanie A. Montgomery, Shawn Hingtgen, Morrent Thang
Publikováno v:
Mol Cancer Ther
Converting human fibroblasts into personalized induced neural stem cells (hiNSC) that actively seek out tumors and deliver cytotoxic agents is a promising approach for treating cancer. Herein, we provide the first evidence that intravenously-infused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf774f4ff861c3543df862b5dfccbdf
https://pubmed.ncbi.nlm.nih.gov/34433662
https://pubmed.ncbi.nlm.nih.gov/34433662
Autor:
Scott R. Floyd, Juli R. Bagó, Wulin Jiang, Alison Mercer-Smith, Alain Valdivia, Simon Khagi, Shawn Hingtgen
Publikováno v:
Neuro Oncol
INTRODUCTION Non-small cell lung cancer (NSCLC) is the most common cancer to form brain metastases. Radiation treatment is standard-of-care, but recurrence is still observed in 40% of patients. An adjuvant treatment is desperately needed to track dow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f13466bcaf7dc09c79bdc3e6116275be
https://europepmc.org/articles/PMC7650905/
https://europepmc.org/articles/PMC7650905/