Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alison M. Worth"'
Autor:
Neeharika Nemani, Edmund Carvalho, Dhanendra Tomar, Zhiwei Dong, Andrea Ketschek, Sarah L. Breves, Fabián Jaña, Alison M. Worth, Julie Heffler, Palaniappan Palaniappan, Aparna Tripathi, Ramasamy Subbiah, Massimo F. Riitano, Ajay Seelam, Thomas Manfred, Kie Itoh, Shuxia Meng, Hiromi Sesaki, William J. Craigen, Sudarsan Rajan, Santhanam Shanmughapriya, Jeffrey Caplan, Benjamin L. Prosser, Donald L. Gill, Peter B. Stathopulos, Gianluca Gallo, David C. Chan, Prashant Mishra, Muniswamy Madesh
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 1005-1019 (2018)
Summary: Mitochondria shape cytosolic calcium ([Ca2+]c) transients and utilize the mitochondrial Ca2+ ([Ca2+]m) in exchange for bioenergetics output. Conversely, dysregulated [Ca2+]c causes [Ca2+]m overload and induces permeability transition pore an
Externí odkaz:
https://doaj.org/article/d8a52722cb5c491eaab6dfcbe01c7e01
Autor:
Dhanendra Tomar, Fabián Jaña, Zhiwei Dong, William J. Quinn, III, Pooja Jadiya, Sarah L. Breves, Cassidy C. Daw, Subramanya Srikantan, Santhanam Shanmughapriya, Neeharika Nemani, Edmund Carvalho, Aparna Tripathi, Alison M. Worth, Xueqian Zhang, Roshanak Razmpour, Ajay Seelam, Stephen Rhode, Anuj V. Mehta, Michael Murray, Daniel Slade, Servio H. Ramirez, Prashant Mishra, Glenn S. Gerhard, Jeffrey Caplan, Luke Norton, Kumar Sharma, Sudarsan Rajan, Darius Balciunas, Dayanjan S. Wijesinghe, Rexford S. Ahima, Joseph A. Baur, Muniswamy Madesh
Publikováno v:
Cell Reports, Vol 26, Iss 13, Pp 3709-3725.e7 (2019)
Summary: Mitochondrial Ca2+ uniporter (MCU)-mediated Ca2+ uptake promotes the buildup of reducing equivalents that fuel oxidative phosphorylation for cellular metabolism. Although MCU modulates mitochondrial bioenergetics, its function in energy home
Externí odkaz:
https://doaj.org/article/77205bbeecaf4261b3e51221d39e06e1
Autor:
Santhanam Shanmughapriya, Andrea Ketschek, William J. Craigen, Julie Heffler, Sudarsan Rajan, Fabián Jaña, David C. Chan, Aparna Tripathi, Ramasamy Subbiah, Benjamin L. Prosser, Massimo F. Riitano, Edmund Carvalho, Shuxia Meng, Jeffrey L. Caplan, Alison M. Worth, Hiromi Sesaki, Palaniappan Palaniappan, Zhiwei Dong, Muniswamy Madesh, Dhanendra Tomar, Thomas Manfred, Neeharika Nemani, Gianluca Gallo, Kie Itoh, Prashant Mishra, Sarah L. Breves, Ajay Seelam, Donald L. Gill, Peter B. Stathopulos
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 1005-1019 (2018)
Summary: Mitochondria shape cytosolic calcium ([Ca2+]c) transients and utilize the mitochondrial Ca2+ ([Ca2+]m) in exchange for bioenergetics output. Conversely, dysregulated [Ca2+]c causes [Ca2+]m overload and induces permeability transition pore an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::051219a2e177b65346e53802ac6cde62
http://www.sciencedirect.com/science/article/pii/S2211124718304741
http://www.sciencedirect.com/science/article/pii/S2211124718304741
Autor:
Xue-Qian Zhang, Annick Judenherc-Haouzi, JuFang Wang, Philippe Haouzi, Fabian Jana Prado, Alison M. Worth, John M. Davidyock, Muniswamy Madesh, Santhanam Shanmughapriya, Jianliang Song, Joseph Y. Cheung
Publikováno v:
Cardiovascular Toxicology. 18:407-419
We have previously demonstrated that methylene blue (MB) counteracts the effects of hydrogen sulfide (H(2)S) cardiotoxicity by improving cardiomyocyte contractility and intracellular Ca(2+) homeostasis disrupted by H(2)S poisoning. In vivo, MB restor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd8db404045eaa627a669a9258fa16f
https://doi.org/10.1007/s12012-018-9451-5
https://doi.org/10.1007/s12012-018-9451-5
Autor:
Dhanendra, Tomar, Fabián, Jaña, Zhiwei, Dong, William J, Quinn, Pooja, Jadiya, Sarah L, Breves, Cassidy C, Daw, Subramanya, Srikantan, Santhanam, Shanmughapriya, Neeharika, Nemani, Edmund, Carvalho, Aparna, Tripathi, Alison M, Worth, Xueqian, Zhang, Roshanak, Razmpour, Ajay, Seelam, Stephen, Rhode, Anuj V, Mehta, Michael, Murray, Daniel, Slade, Servio H, Ramirez, Prashant, Mishra, Glenn S, Gerhard, Jeffrey, Caplan, Luke, Norton, Kumar, Sharma, Sudarsan, Rajan, Darius, Balciunas, Dayanjan S, Wijesinghe, Rexford S, Ahima, Joseph A, Baur, Muniswamy, Madesh
Publikováno v:
Cell reports. 26(13)
Mitochondrial Ca(2+) uniporter (MCU)-mediated Ca(2+) uptake promotes the buildup of reducing equivalents that fuel oxidative phosphorylation for cellular metabolism. Although MCU modulates mitochondrial bioenergetics, its function in energy homeostas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9cb1dd577e7e85a80b77f7869be946d
https://pubmed.ncbi.nlm.nih.gov/30917323
https://pubmed.ncbi.nlm.nih.gov/30917323
Autor:
Darius Balciunas, Jeffrey L. Caplan, Prashant Mishra, Glenn S. Gerhard, Muniswamy Madesh, Sarah L. Breves, Xue-Qian Zhang, Subramanya Srikantan, Dhanendra Tomar, Stephen Rhode, Ajay Seelam, Santhanam Shanmughapriya, Kumar Sharma, Sudarsan Rajan, Daniel Slade, Servio H. Ramirez, Dayanjan S. Wijesinghe, Rexford S. Ahima, Aparna Tripathi, Fabián Jaña, Michael D. Murray, Cassidy C. Daw, Anuj V. Mehta, William J. Quinn, Pooja Jadiya, Edmund Carvalho, Neeharika Nemani, Zhiwei Dong, Alison M. Worth, Luke Norton, Joseph A. Baur, Roshanak Razmpour
Publikováno v:
Cell Reports, Vol 26, Iss 13, Pp 3709-3725.e7 (2019)
Summary: Mitochondrial Ca2+ uniporter (MCU)-mediated Ca2+ uptake promotes the buildup of reducing equivalents that fuel oxidative phosphorylation for cellular metabolism. Although MCU modulates mitochondrial bioenergetics, its function in energy home
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77fb442f094ee2137918eb3dd246c905
https://doi.org/10.1016/j.celrep.2019.02.107
https://doi.org/10.1016/j.celrep.2019.02.107
Autor:
Zhiwei, Dong, Santhanam, Shanmughapriya, Dhanendra, Tomar, Naveed, Siddiqui, Solomon, Lynch, Neeharika, Nemani, Sarah L, Breves, Xueqian, Zhang, Aparna, Tripathi, Palaniappan, Palaniappan, Massimo F, Riitano, Alison M, Worth, Ajay, Seelam, Edmund, Carvalho, Ramasamy, Subbiah, Fabián, Jaña, Jonathan, Soboloff, Yizhi, Peng, Joseph Y, Cheung, Suresh K, Joseph, Jeffrey, Caplan, Sudarsan, Rajan, Peter B, Stathopulos, Muniswamy, Madesh
Publikováno v:
Molecular cell. 65(6)
Ca2+ dynamics and oxidative signaling are fundamental mechanisms for mitochondrial bioenergetics and cell function. The MCU complex is the major pathway by which these signals are integrated in mitochondria. Whether and how these coactive elements in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c851686779558880a1e20feaa789cd1e
https://pubmed.ncbi.nlm.nih.gov/28262504
https://pubmed.ncbi.nlm.nih.gov/28262504
Autor:
Yizhi Peng, Sudarsan Rajan, Jonathan Soboloff, Xue-Qian Zhang, Jeffrey L. Caplan, Peter B. Stathopulos, Aparna Tripathi, Neeharika Nemani, Ramasamy Subbiah, Joseph Y. Cheung, Fabián Jaña, Zhiwei Dong, Solomon Lynch, Massimo F. Riitano, Ajay Seelam, Palaniappan Palaniappan, Alison M. Worth, Dhanendra Tomar, Sarah L. Breves, Edmund Carvalho, Naveed Siddiqui, Muniswamy Madesh, Santhanam Shanmughapriya, Suresh K. Joseph
Publikováno v:
Molecular Cell. 65:1014-1028.e7
Ca2+ dynamics and oxidative signaling are fundamental mechanisms for mitochondrial bioenergetics and cell function. The MCU complex is the major pathway by which these signals are integrated in mitochondria. Whether and how these coactive elements in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9baa5346b3d8d18610ba912a1b8ac164
https://doi.org/10.1016/j.molcel.2017.01.032
https://doi.org/10.1016/j.molcel.2017.01.032