Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Alison M. Urvalek"'
Autor:
Lorraine J. Gudas, Alison M. Urvalek, Xiao-Han Tang, Kwame Osei-Sarfo, Theresa Scognamiglio, Tuo Zhang
Publikováno v:
Oncotarget
// Xiao-Han Tang 1 , Alison M. Urvalek 1,* , Kwame Osei-Sarfo 1,* , Tuo Zhang 2 , Theresa Scognamiglio 3 and Lorraine J. Gudas 1 1 Department of Pharmacology, Weill Cornell Medical College, New York, NY, USA 2 Genomics Resources Core Facility, Weill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4fb5bd50dc767414c8f6a958350f19
https://doi.org/10.18632/oncotarget.4420
https://doi.org/10.18632/oncotarget.4420
Publikováno v:
The Journal of biological chemistry. 294(14)
Ethanol (EtOH) is a teratogen, but its teratogenic mechanisms are not fully understood. The alcohol form of vitamin A (retinol/ROL) can be oxidized to all-trans-retinoic acid (RA), which plays a critical role in stem cell differentiation and developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a79e6d1b3cd5b17a489773acdb32d3
https://pubmed.ncbi.nlm.nih.gov/30737277
https://pubmed.ncbi.nlm.nih.gov/30737277
Autor:
Kwame Osei-Sarfo, Alison M. Urvalek, Xiao-Han Tang, Tuo Zhang, Lorraine J. Gudas, Theresa Scognamiglio
Publikováno v:
Alcoholism: Clinical and Experimental Research. 39:1360-1372
Background Head and neck squamous cell carcinoma (HNSCC) is a cancer that is characterized by its high morbidity and mortality rates. While tobacco use and alcohol consumption are 2 major contributing factors for HNSCC carcinogenesis, how the combina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d557829f11a01420a221c44ba2fb4de
https://doi.org/10.1111/acer.12772
https://doi.org/10.1111/acer.12772
Autor:
Debarati Mukherjee, Lin Yu, Jihe Zhao, Liu Hu, Xianhui Wang, Tianshu Li, Chao Shen, Alison M. Urvalek, Heng Lu, Melissa S. Wason, Satadru K. Lahiri
Publikováno v:
Oncogene
Krüppel-like factor 8 (KLF8) regulates critical gene transcription associated with cancer. The underlying mechanisms, however, remain largely unidentified. We have recently demonstrated that KLF8 expression enhances the activity but not expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef570d54fa8484f9f22814e7eb5c345a
http://europepmc.org/articles/PMC3929536
http://europepmc.org/articles/PMC3929536
Publikováno v:
Oncogene
We have previously demonstrated that Krüppel-like factor 8 (KLF8) participates in oncogenic transformation of mouse fibroblasts and is highly overexpressed in human ovarian cancer. In this work, we first correlated KLF8 overexpression with the aggre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c3f0c6733579fa93a562579c0ac13e
https://doi.org/10.1038/onc.2012.545
https://doi.org/10.1038/onc.2012.545
KLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9
Autor:
Paul J. Feustel, Alison M. Urvalek, Tianshu Li, Xianhui Wang, C M DiPersio, Lin Yu, John M. Lamar, Jihe Zhao, Heng Lu
Publikováno v:
Oncogene
Epithelial to mesenchymal transition (EMT) and extracellular matrix degradation are critical for the initiation and progression of tumor invasion. We have recently identified Krüppel-like factor 8 (KLF8) as a critical inducer of EMT and invasion. KL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00fd81254b3ad40c72dc5408ef4287de
https://doi.org/10.1038/onc.2010.563
https://doi.org/10.1038/onc.2010.563
Autor:
Jameson Q Ma, Heng Lu, Jihe Zhao, Kim-Hang H Nguyen, Alison M. Urvalek, Jojo D Hammond, Xianhui Wang, Farah Monzur, Tina S. Mehta
Publikováno v:
Cell Research. 19:1098-1109
Kruppel-like factor 8 (KLF8) transcription factor plays a critical role in cell cycle progression, oncogenic transformation, epithelial to mesenchymal transition and invasion. However, its nuclear localization signal(s) (NLS) has not been identified.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ae62726ceacb9160af082a5d334c274
https://doi.org/10.1038/cr.2009.64
https://doi.org/10.1038/cr.2009.64
Publikováno v:
Journal of Biological Chemistry. 283:13934-13942
KLF8 (Krüppel-like factor 8) is a transcription factor downstream of focal adhesion kinase (FAK) important in the regulation of the cell cycle and also plays a critical role in oncogenic transformation and epithelial to mesenchymal transition. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d8fa53a53bea63274ff4150415103bd
https://doi.org/10.1074/jbc.m709300200
https://doi.org/10.1074/jbc.m709300200
Publikováno v:
Oncotarget
Esophageal squamous cell carcinomas (ESCCs) are very common, aggressive tumors, and are often associated with alcohol and tobacco abuse. Because ESCCs exhibit high recurrence rates and are diagnosed at late stages, identification of prognostic and dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52ff5f2c0ed8c6f77dfdbf8be875bcf
https://pubmed.ncbi.nlm.nih.gov/25714027
https://pubmed.ncbi.nlm.nih.gov/25714027
Autor:
Xiao-Han Tang, Lorraine J. Gudas, Alison M. Urvalek, Theresa Scognamiglio, Tuo Zhang, Kwame Osei-Sarfo
We investigated the effects of bexarotene (a retinoid X receptor agonist), CD1530 (a retinoic acid receptor γ selective agonist), and the combination of these two drugs for the prevention of oral carcinogenesis induced by the carcinogen 4-nitroquino
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1f8244dfb2947f8b160989c7b7f97c
https://europepmc.org/articles/PMC4066471/
https://europepmc.org/articles/PMC4066471/
