Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Alison M. Pecquet"'
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-6 (2020)
Abstract Objective Perfluorooctanoic acid (PFOA) is a ubiquitous environmental contaminant and a known immune suppressant in humans and experimental animal models. Studies on PFOA have focused on suppression of the adaptive immune response; however,
Externí odkaz:
https://doaj.org/article/ece55a6e637e486b822bd51826b2dcd8
Publikováno v:
International Journal of Environmental Research and Public Health; Volume 19; Issue 15; Pages: 9490
For the past several decades, a relative potency approach has been used to estimate the human health risks from exposure to polycyclic aromatic hydrocarbon (PAH) mixtures. Risk estimates are derived using potency equivalence factors (PEFs; also calle
Publikováno v:
Integrated Environmental Assessment and Management
The purpose of this study was to identify, characterize, and assess data needs for ecological risk of household cleaning product polymers currently being used in the United States (US). Because of their range in properties and functions, polymers are
Publikováno v:
BMC Research Notes
BMC Research Notes, Vol 13, Iss 1, Pp 1-6 (2020)
BMC Research Notes, Vol 13, Iss 1, Pp 1-6 (2020)
Objective Perfluorooctanoic acid (PFOA) is a ubiquitous environmental contaminant and a known immune suppressant in humans and experimental animal models. Studies on PFOA have focused on suppression of the adaptive immune response; however, little is
Autor:
Jeanelle M. Martinez, Alison M. Pecquet, Melissa J. Vincent, Neeraja Erraguntla, Michael L. Dourson
Publikováno v:
Journal of Applied Toxicology
A no‐significant‐risk‐level of 20 mg day–1 was derived for tetrabromobisphenol A (TBBPA). Uterine tumors (adenomas, adenocarcinomas, and malignant mixed Müllerian) observed in female Wistar Han rats from a National Toxicology Program 2‐yea
Autor:
Robert G. Sussman, Ester Lovsin Barle, Eileen P. Hayes, Alison M. Pecquet, Lance R. Molnar, Bruce D. Naumann, Patricia A. Weideman, Bryan K. Shipp, Michael J. Olson, Robert A. Jolly, Ellen C. Faria
Publikováno v:
Regulatory Toxicology and Pharmacology. 79:S19-S27
This manuscript centers on communication with key stakeholders of the concepts and program goals involved in the application of health-based pharmaceutical cleaning limits. Implementation of health-based cleaning limits, as distinct from other standa
Autor:
Lance R. Molnar, Ellen C. Faria, Ester Lovsin Barle, Joel P. Bercu, Alison M. Pecquet, Michael J. Olson, Bryan K. Shipp, Robert G. Sussman, Robert A. Jolly, Bruce D. Naumann, Reena Sandhu, Eileen P. Hayes, Patricia A. Weideman
Publikováno v:
Regulatory Toxicology and Pharmacology. 79:S39-S47
A European Union (EU) regulatory guideline came into effect for all new pharmaceutical products on June 1st, 2015, and for all existing pharmaceutical products on December 1st, 2015. This guideline centers around the use of the Acceptable Daily Expos
Autor:
Eric Morinello, Patricia A. Weideman, Ellen C. Faria, Claudia Sehner, David G. Dolan, Joel P. Bercu, Christopher Seaman, Alison M. Pecquet
Publikováno v:
Regulatory Toxicology and Pharmacology. 79:S28-S38
This manuscript discusses the different historical and more recent default approaches that have been used to derive an acceptable daily exposure (ADE). While it is preferable to derive a health-based ADE based on a complete nonclinical and clinical d
Autor:
Charles Pittinger, Alison M. Pecquet
Publikováno v:
Environmental science and pollution research international. 25(15)
This paper summarizes the historical and recent research on the aquatic toxicology and bioconcentration potential of tetrabromobisphenol A (TBBPA), a major flame retardant in electronics. Historical studies on TBBPA are presented in detail, and are c
Autor:
Anthony J. Streeter, John F. Reichard, Alison M. Pecquet, Reena Sandhu, Bruce D. Naumann, M. Andrew Maier, Patricia A. Weideman, Thomas Pfister, Edward V. Sargent
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 79
The purpose of this paper is to describe the use of toxicokinetic (TK) and toxicodynamic (TD) data in setting acceptable daily exposure (ADE) values and occupational exposure limits (OELs). Use of TK data can provide a more robust exposure limit base