Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Alison M. Layton"'
Autor:
Brima M. Younis, Rebecca Wiggins, Eltahir A.G. Khalil, Mohamed Osman, Francesco Santoro, Chiara Sonnati, Ada Keding, Maria Novedrati, Giorgio Montesi, Ali Noureldein, Elmukashfi T.A. Elmukashfi, Ala Eldin Mustafa, Mohammed Alamin, Mohammed Saeed, Khalid Salman, Ahmed J. Suliman, Amin E.A. Musa, Alison M. Layton, Charles J.N. Lacey, Paul M. Kaye, Ahmed M. Musa
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 3, Pp 101310- (2024)
In a recent phase 2a clinical trial, the candidate leishmaniasis vaccine ChAd63-KH was shown to be safe and immunogenic in Sudanese patients with post kala-azar dermal leishmaniasis (PKDL). However, its value as a stand-alone therapeutic was unknown.
Externí odkaz:
https://doaj.org/article/a583923d15cf4d3cb40a6f85f30978df
Publikováno v:
Dermatology Reports (2024)
Acne (syn. acne vulgaris) is a common inflammatory skin disorder associated with puberty and adolescence. Driven by complex interactions between the pilosebaceous unit and Cutibacterium acnes (C. acnes) bacteria, the disease is characterised by comed
Externí odkaz:
https://doaj.org/article/8722cdb52e574dccb033dab0ab41794f
Autor:
Cherish Boxall, Susanne Renz, Zina Eminton, Jacqueline Nuttall, Alan Saji, Charlotte Cluff, Christopher Wilcox, Ingrid Muller, Alison M. Layton, Irene Soulsby, Miriam Santer
Publikováno v:
Trials, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background The use of decentralised clinical trials (which bring trials to patients through remote processes and technology versus central on-site visits) has been thought to be a potential solution to common recruitment and retention barrie
Externí odkaz:
https://doaj.org/article/e5654ea39e4349f08009e6f469d0c5c4
Autor:
Aoife U. Daly, Rui Baptista Gonçalves, Eva Lau, Joanne Bowers, Naayema Hussaini, Maria Charalambides, Jack Coumbe, Carsten Flohr, Alison M. Layton
Publikováno v:
JEADV Clinical Practice, Vol 2, Iss 3, Pp 432-449 (2023)
Abstract How does low‐dose oral isotretinoin compare with recommended and high‐dose oral isotretinoin in terms of efficacy, adverse effect profile, duration of remission, economic profile and rate and severity of relapse? A systematic literature
Externí odkaz:
https://doaj.org/article/5435751a00a84076ad16f3aacc08d0aa
Autor:
Alison M. Layton, MB ChB, Andrew Alexis, MD, MPH, Hilary Baldwin, MD, Vincenzo Bettoli, MD, James Del Rosso, DO, Thomas Dirschka, MD, Brigitte Dréno, MD, PhD, Linda Stein Gold, MD, Julie Harper, MD, Joo Yeon Ko, MD, PhD, Khaled Al Nuaimi, MD, Hazel H. Oon, MD, Murlidhar Rajagopalan, MD, MBBS, Marco Rocha, MD, PhD, Jo-Ann See, MBBS, Jonathan Weiss, MD, Jerry Tan, MD
Publikováno v:
JAAD International, Vol 12, Iss , Pp 60-69 (2023)
Background: Acne, a commonly treated skin disease, requires patient-centered management due to its varying presentations, chronicity, and impact on health-related quality of life. Despite this, evidence-based clinical guidelines focus primarily on cl
Externí odkaz:
https://doaj.org/article/11bd54c939e14b30b7b834f62a207422
Autor:
Louise Corcoran, Ingrid Muller, Alison M. Layton, Gwennan Rucinski, Viktoria Venkatess, Anicka Sufraz, Sophie Dove, Mark Lown, Beth Stuart, Nick Francis, Miriam Santer
Publikováno v:
Skin Health and Disease, Vol 3, Iss 4, Pp n/a-n/a (2023)
Abstract Background Acne is very common, can cause considerable negative impact on quality of life and there is increasing concern over the use of long courses of oral antibiotics for this condition. Objectives (1) To critically appraise reporting in
Externí odkaz:
https://doaj.org/article/690227acb1d64c7688b2c91bd205a825
Autor:
Jerry Tan, MD, Andrew Alexis, MD, MPH, Hilary Baldwin, MD, Stefan Beissert, MD, Vincenzo Bettoli, MD, James Del Rosso, DO, Brigitte Dréno, MD, PhD, Linda Stein Gold, MD, Julie Harper, MD, Charles Lynde, MD, Diane Thiboutot, MD, Jonathan Weiss, MD, Alison M. Layton, MB ChB
Publikováno v:
JAAD International, Vol 5, Iss , Pp 33-40 (2021)
Background: Truncal acne is common and burdensome for patients; however, there is paucity of evidence and guidance for the management of truncal acne. Currently, clinical practice guidelines provide very little guidance on the assessment or managemen
Externí odkaz:
https://doaj.org/article/f5365911c8ae4858a235db920b65f747
Autor:
Jerry Tan, MD, Andrew Alexis, MD, MPH, Hilary Baldwin, MD, Stefan Beissert, MD, Vincenzo Bettoli, MD, James Del Rosso, DO, Brigitte Dréno, MD, PhD, Linda Stein Gold, MD, Julie Harper, MD, Charles Lynde, MD, Diane Thiboutot, MD, Jonathan Weiss, MD, Alison M. Layton, MB ChB
Publikováno v:
JAAD International, Vol 5, Iss , Pp 101-111 (2021)
Background: Acne is a chronic disease with a varying presentation that requires long-term management. Despite this, the clinical guidelines for acne offer limited guidance to facilitate personalized or longitudinal management of patients. Objectives:
Externí odkaz:
https://doaj.org/article/e549f1b6d3d14ae284abda8a5491fae5
Autor:
Vivak Parkash, Georgina Jones, Nina Martin, Morgan Steigmann, Elizabeth Greensted, Paul Kaye, Alison M. Layton, Charles J. Lacey
Publikováno v:
Research Involvement and Engagement, Vol 7, Iss 1, Pp 1-12 (2021)
Plain English summary Our research team is designing a type of research study known as a controlled human infection model (CHIM). In CHIM studies, volunteers are exposed to infections on purpose and then studied to help understand diseases. Similar e
Externí odkaz:
https://doaj.org/article/c08584d30cc84f3ab8e4c7e6c194c60d
Autor:
Helen Ashwin, Jovana Sadlova, Barbora Vojtkova, Tomas Becvar, Patrick Lypaczewski, Eli Schwartz, Elizabeth Greensted, Katrien Van Bocxlaer, Marion Pasin, Kai S. Lipinski, Vivak Parkash, Greg Matlashewski, Alison M. Layton, Charles J. Lacey, Charles L. Jaffe, Petr Volf, Paul M. Kaye
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Controlled human infection models (CHIMs) provide a pathway for accelerating vaccine development. Here, the authors describe the isolation, characterization, and GMP manufacture of a clinical Leishmania major strain to be used as a resource for CHIM
Externí odkaz:
https://doaj.org/article/ddd377d986694040985714870d5c4e1c