Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Alison M. Day"'
Autor:
Yasmin Ahmed, Mélanie A. C. Ikeh, Donna M. MacCallum, Alison M. Day, Kevin Waldron, Janet Quinn
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT The ability of pathogenic fungi to obtain essential nutrients from the host is vital for virulence. In Candida albicans, acquisition of the macronutrient phosphate is regulated by the Pho4 transcription factor and is important for both virul
Externí odkaz:
https://doaj.org/article/705e6bf7868e48a98baa465733475fa2
Autor:
Alison M. Day, Janet Quinn
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)
The ability of fungal pathogens to survive hostile environments within the host depends on rapid and robust stress responses. Stress-activated protein kinase (SAPK) pathways are conserved MAPK signaling modules that promote stress adaptation in all e
Externí odkaz:
https://doaj.org/article/0af693e89da74f2bb2ce74bc88d008b3
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
ABSTRACT Candida auris has recently emerged as an important, multidrug-resistant fungal pathogen of humans. Comparative studies indicate that despite high levels of genetic divergence, C. auris is as virulent as the most pathogenic member of the genu
Externí odkaz:
https://doaj.org/article/b65f9f3705c24e72856d0a7382943bae
Autor:
Carmen Herrero-de-Dios, Alison M. Day, Anna T. Tillmann, Stavroula L. Kastora, David Stead, Paula S. Salgado, Janet Quinn, Alistair J. P. Brown
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT In all eukaryotic kingdoms, mitogen-activated protein kinases (MAPKs) play critical roles in cellular responses to environmental cues. These MAPKs are activated by phosphorylation at highly conserved threonine and tyrosine residues in respon
Externí odkaz:
https://doaj.org/article/f5b73d7ef4194195a32a24d030a681c5
Autor:
Jonathon D. Brown, Alison M. Day, Sarah R. Taylor, Lewis E. Tomalin, Brian A. Morgan, Elizabeth A. Veal
Publikováno v:
Cell Reports, Vol 5, Iss 5, Pp 1425-1435 (2013)
H2O2 can cause oxidative damage associated with age-related diseases such as diabetes and cancer but is also used to initiate diverse responses, including increased antioxidant gene expression. Despite significant interest, H2O2-signaling mechanisms
Externí odkaz:
https://doaj.org/article/9cc8c00a0d4343e0af668d7ca601d652
Autor:
Artur Rogowski, Jonathon A. Briggs, Jennifer C. Mortimer, Theodora Tryfona, Nicolas Terrapon, Elisabeth C. Lowe, Arnaud Baslé, Carl Morland, Alison M. Day, Hongjun Zheng, Theresa E. Rogers, Paul Thompson, Alastair R. Hawkins, Madhav P. Yadav, Bernard Henrissat, Eric C. Martens, Paul Dupree, Harry J. Gilbert, David N. Bolam
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-1 (2016)
Nature Communications 6 Article number: 7481 (2015); Published 26 June 2015; Updated 5 February 2016 The financial support for the work described in this Article was not fully acknowledged. The Acknowledgements should have included the following: Thi
Externí odkaz:
https://doaj.org/article/7ddadafb7d2b45ecb856aa5c8c311b75
Autor:
Min Cao, Alison M Day, Martin Galler, Heather Latimer, Dominic P Byrne, Emilia Dwyer, Elise Bennett, Patrick A Eyers, Elizabeth A Veal
SummaryPeroxiredoxins (Prdx) utilize reversibly oxidized cysteine residues to reduce peroxides but also to promote H2O2signal transduction, including H2O2-induced activation of P38 MAPK. Prdx form H2O2-induced disulfide complexes with many proteins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e4ecec64f8f9d57b55118135dd062b3
https://doi.org/10.1101/2022.11.15.513554
https://doi.org/10.1101/2022.11.15.513554
Autor:
Alison M. Day, Carmen M. Herrero-de-Dios, Donna M. MacCallum, Alistair J. P. Brown, Janet Quinn
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Stress-activated protein kinase (SAPK) pathways are evolutionarily conserved eukaryotic signalling modules that are essential for the virulence of human pathogenic fungi. The Hog1 SAPK in Candida albicans is robustly phosphorylated in response to a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::f8d82cc3211f34a8db9f409da54e736e
http://link.springer.com/article/10.1038/s41598-017-14756-4
http://link.springer.com/article/10.1038/s41598-017-14756-4
Autor:
Elizabeth A. Veal, Tobias B. Dansen, Martin Galler, Janet Quinn, Alison M. Day, Heather Latimer, Harmjan R. Vos
Publikováno v:
Access Microbiology. 1
In order to protect against oxidative damage, cells have evolved a host of ROS-detoxifying enzymes. These include peroxiredoxins, a highly conserved family of thioredoxin peroxidases. Unexpectedly, given their role in lowering H2O2levels, peroxiredox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d87bee128ce350bd3a50457857e7eba
https://doi.org/10.1099/acmi.byg2019.po0019
https://doi.org/10.1099/acmi.byg2019.po0019
Publikováno v:
Access Microbiology. 1
The emerging fungal pathogen Candida auris is responsible for recent global outbreaks caused by genetically divergent clades that, alarmingly, display multi-drug resistance to currently available antifungals. Although not much is known about the path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1bf4ddc4160a9db75cecc6f72b1a9aa
https://doi.org/10.1099/acmi.byg2019.po0015
https://doi.org/10.1099/acmi.byg2019.po0015