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pro vyhledávání: '"Alison M. Bates"'
Publikováno v:
Cells, Vol 8, Iss 5, p 414 (2019)
Telomere dysfunction has been strongly implicated in the initiation of genomic instability and is suspected to be an early event in the carcinogenesis of human solid tumors. Recent findings have established the presence of telomere fusions in human b
Externí odkaz:
https://doaj.org/article/059ba90ad72f49779ec0d28617902a07
Autor:
Qiujia Chen, Alison M. Bates, Jocelyne N. Hanquier, Edward Simpson, Douglas B. Rusch, Ram Podicheti, Yunlong Liu, Ronald C. Wek, Evan M. Cornett, Millie M. Georgiadis
Publikováno v:
The Journal of biological chemistry. 298(5)
Extensive portions of the human genome have unknown function, including those derived from transposable elements. One such element, the DNA transposon Hsmar1, entered the primate lineage approximately 50 million years ago leaving behind terminal inve
Autor:
Janaiah Kota, Smiti Snigdha Sahu, Hiromi Tanaka, Guanglong Jiang, Sarah C. Nabinger, Yunlong Liu, Shatovisha Dey, Alison M. Bates
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Colorectal cancer (CRC) is the fourth leading cause of cancer-related deaths worldwide. Liver metastasis is the major cause of CRC patient mortality, occurring in 60% patients with no effective therapies. Although studies have indicated the role of m
Publikováno v:
Cells, Vol 8, Iss 5, p 414 (2019)
Cells
Volume 8
Issue 5
Cells
Volume 8
Issue 5
Telomere dysfunction has been strongly implicated in the initiation of genomic instability and is suspected to be an early event in the carcinogenesis of human solid tumors. Recent findings have established the presence of telomere fusions in human b
Autor:
Nilesh B. Karalkar, Hyo Joong Kim, Andrew D. Ellington, Myong Jung Kim, Steven A. Benner, Shuichi Hoshika, John SantaLucia, Norman E. Watkins, Joseph A. Piccirilli, Alison M. Bates, Nicole A. Leal, Holly A. SantaLucia, Adam J. Meyer, Millie M. Georgiadis, Myong Sang Kim, Saurja DasGupta
Publikováno v:
Biochemistry
Steve Benner and collaborators have recently reported an analysis of DNA containing eight nucleotide letters – the four natural letters dG, dC, dA, and dT, and four additional letters, called dP, dZ, dS, and dB. Their analysis demonstrates that the
Autor:
Brenda R. Grimes, Roger B. Slee, Nazmul Huda, David Gilley, LiRen Tu, Liang Cheng, Alison M. Bates
Publikováno v:
Molecular Carcinogenesis. 55:842-852
A critical function of the telomere is to disguise chromosome ends from cellular recognition as double strand breaks, thereby preventing aberrant chromosome fusion events. Such chromosome end-to-end fusions are known to initiate genomic instability v
Autor:
LiRen, Tu, Nazmul, Huda, Brenda R, Grimes, Roger B, Slee, Alison M, Bates, Liang, Cheng, David, Gilley
Publikováno v:
Molecular carcinogenesis. 55(5)
A critical function of the telomere is to disguise chromosome ends from cellular recognition as double strand breaks, thereby preventing aberrant chromosome fusion events. Such chromosome end-to-end fusions are known to initiate genomic instability v