Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Alison L. Müller"'
Autor:
Alison L. Müller, Naranjan S. Dhalla
Publikováno v:
Pharmaceuticals, Vol 3, Iss 7, Pp 2111-2145 (2010)
Protein kinases are intimately integrated in different signal transduction pathways for the regulation of cardiac function in both health and disease. Protein kinase A (PKA), Ca2+-calmodulin-dependent protein kinase (CaMK), protein kinase C (PKC), ph
Externí odkaz:
https://doaj.org/article/9a646367f6c4420491a32177471826f3
Publikováno v:
Journal of Applied Physiology. 114:351-360
Previous studies have shown that ischemia-reperfusion (I/R) injury is associated with cardiac dysfunction and changes in sarcolemmal Na+-K+-ATPase subunits and activity. This study was undertaken to evaluate the role of proteases in these alterations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f619fe726d1fb8ba54431c02a587fd91
https://doi.org/10.1152/japplphysiol.01239.2012
https://doi.org/10.1152/japplphysiol.01239.2012
Autor:
Alison L. Müller, Naranjan S. Dhalla
Publikováno v:
Current Cardiology Reviews
Cardiac function is compromised by oxidative stress which occurs upon exposing the heart to ischemia reperfusion (I/R) for a prolonged period. The reactive oxygen species (ROS) that are generated during I/R incur extensive damage to the myocardium an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64165e26484a70ee15d81ca4a62a801a
http://europepmc.org/articles/PMC3083806
http://europepmc.org/articles/PMC3083806
Autor:
Alison L Müller, Darren H Freed
Publikováno v:
Circulation Research. 117
There are many cell types that can contribute to cardiac fibrosis including atrial fibroblasts (AFs) and bone marrow-derived progenitor cells (MPCs). We have previously shown that MPCs display a myofibroblast phenotype in vitro which is linked to alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05e73ad3c722c8264aff860fedfe38fc
https://doi.org/10.1161/res.117.suppl_1.224
https://doi.org/10.1161/res.117.suppl_1.224
Autor:
Alison L. Müller, Yun Li, Rakesh C. Arora, Hoa Le, Ganghong Tian, Brett Hiebert, E. Ambrose, T.W. Lee, Jayan Nagendran, Darren H. Freed, Ian M.C. Dixon, Christopher W. White, Larry V. Hryshko
Ex vivo heart perfusion (EVHP) may facilitate resuscitation of discarded donor hearts and expand the donor pool; however, a reliable means of demonstrating organ viability prior to transplantation is required. Therefore, we sought to identify metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff76d7a6654c35d749acc2d3693fada3
https://nrc-publications.canada.ca/eng/view/object/?id=76d90894-da08-4374-a188-1f76dff02efa
https://nrc-publications.canada.ca/eng/view/object/?id=76d90894-da08-4374-a188-1f76dff02efa
Autor:
Darren H. Freed, Alison L. Müller
Publikováno v:
Current molecular pharmacology. 10(1)
Inhibition of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase by pharmaceuticals, commonly referred to as statins, has proven to be an effective and efficient way in reducing cholesterol levels in patients. As a result of this intervention, meva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62358dc8669bee3a69ba19b14e5e27ea
https://pubmed.ncbi.nlm.nih.gov/26758946
https://pubmed.ncbi.nlm.nih.gov/26758946
Publikováno v:
Circulation Research. 115
Differentiation of human mesenchymal stem cells (hMSCs) has been shown to be influenced by the surrounding microenvironment. It is important to understand the physiological implications of the hMSC microenvironment regarding differentiation within th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e720dad9b6e62da6f32f8b175aee7f74
https://doi.org/10.1161/res.115.suppl_1.12
https://doi.org/10.1161/res.115.suppl_1.12
Autor:
Christopher W. White, Julianne Klein, Stephen R. Large, P. Mundt, Amir Ravandi, Devin Hasanally, E. Ambrose, Darren H. Freed, Bo Xiang, Yun Li, Alison L. Müller, Rakesh C. Arora, T.W. Lee, Ganghong Tian, Larry V. Hryshko
Publikováno v:
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 34(1)
Ex vivo heart perfusion (EVHP) provides the opportunity to resuscitate unused donor organs and facilitates assessments of myocardial function that are required to demonstrate organ viability before transplantation. We sought to evaluate the effect of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15bb1e87a916bf17526a949f90dcc677
https://pubmed.ncbi.nlm.nih.gov/35760461
https://pubmed.ncbi.nlm.nih.gov/35760461
Publikováno v:
The FASEB Journal. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75bf12d2c4bb50ac9f3b320c1aa509e1
https://doi.org/10.1096/fasebj.28.1_supplement.868.4
https://doi.org/10.1096/fasebj.28.1_supplement.868.4
Autor:
Ganghong Tian, Yun Li, Melanie A. Ngo, Darren H. Freed, Shannon Neumann, Ian M.C. Dixon, Rakesh C. Arora, Alison L. Müller
Cardiac fibrosis accompanies a variety of myocardial disorders, and is induced by myofibroblasts. These cells may be composed of a heterogeneous population of parent cells, including interstitial fibroblasts and circulating progenitor cells. Direct c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93e871ae9a945a40f6d6f754329d11e
https://doi.org/10.1007/s11010-014-2030-6
https://doi.org/10.1007/s11010-014-2030-6