Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Alison K. Gillingham"'
Autor:
John J. H. Shin, Oliver M. Crook, Alicia C. Borgeaud, Jérôme Cattin-Ortolá, Sew Y. Peak-Chew, Lisa M. Breckels, Alison K. Gillingham, Jessica Chadwick, Kathryn S. Lilley, Sean Munro
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The vesicles that transport proteins between intracellular organelles are small, short-lived, and elusive. Here, the authors show that capture of these vesicles through relocalizing tethers to mitochondria allows their contents to be characterised by
Externí odkaz:
https://doaj.org/article/1913f75e498144daac7560db0fab4bbd
Publikováno v:
Biology Open, Vol 5, Iss 7, Pp 987-992 (2016)
The use of Drosophila melanogaster as a model organism has been pivotal to understanding the developmental processes of metazoans. However, the use of flies for studying subcellular organization is hampered by a paucity of reliable reagents to label
Externí odkaz:
https://doaj.org/article/223eec48bea942b0ac6c6ce473cc98d3
Autor:
Aleš Holfeld, Dina Schuster, Fabian Sesterhenn, Alison K Gillingham, Patrick Stalder, Walther Haenseler, Inigo Barrio-Hernandez, Dhiman Ghosh, Jane Vowles, Sally A Cowley, Luise Nagel, Basavraj Khanppnavar, Tetiana Serdiuk, Pedro Beltrao, Volodymyr M Korkhov, Sean Munro, Roland Riek, Natalie de Souza, Paola Picotti
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 6, Pp 651-675 (2024)
Abstract The physical interactome of a protein can be altered upon perturbation, modulating cell physiology and contributing to disease. Identifying interactome differences of normal and disease states of proteins could help understand disease mechan
Externí odkaz:
https://doaj.org/article/111e459619b140979ac5a006ab8a5025
Publikováno v:
eLife, Vol 8 (2019)
The GTPases of the Ras superfamily regulate cell growth, membrane traffic and the cytoskeleton, and a wide range of diseases are caused by mutations in particular members. They function as switchable landmarks with the active GTP-bound form recruitin
Externí odkaz:
https://doaj.org/article/91446bfa1e7545609e545778781bfb5f
Autor:
Kathryn S. Lilley, Lisa M. Breckels, Alicia C. Borgeaud, John J. H. Shin, Sean Munro, Sew Y. Peak-Chew, Alison K. Gillingham, Oliver M. Crook, Jérôme Cattin-Ortolá, Jessica Chadwick
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Intracellular traffic between compartments of the secretory and endocytic pathways is mediated by vesicle-based carriers. The proteomes of carriers destined for many organelles are ill-defined because the vesicular intermediates are transient, low-ab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c568dd0951ac571e0ddd297a7c5f355
Autor:
Alison K Gillingham, Sean Munro
Publikováno v:
PLoS ONE, Vol 2, Iss 9, p e842 (2007)
Small G proteins of the Arf and Rab families are fundamental to the organisation and activity of intracellular membranes. One of the most well characterised of these G proteins is mammalian Arf6, a protein that participates in many cellular processes
Externí odkaz:
https://doaj.org/article/c0f8202629f044e4befd7f3ec797ca04
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
The GTPases of the Ras superfamily regulate cell growth, membrane traffic and the cytoskeleton, and a wide range of diseases are caused by mutations in particular members. They function as switchable landmarks with the active GTP-bound form recruitin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c98aff044affc2e01cc471880b1470
https://elifesciences.org/articles/45916
https://elifesciences.org/articles/45916
Autor:
Sean Munro, Alison K. Gillingham
Publikováno v:
Current opinion in cell biology. 59
All cells contain numerous membrane-bound organelles that carry out specific functions. These compartments do not, however, act in isolation. Some are in direct contact via membrane contact sites, while others exchange material via specific vesicles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212e8d2105a0a9587b81da4884ff36a1
https://pubmed.ncbi.nlm.nih.gov/31154044
https://pubmed.ncbi.nlm.nih.gov/31154044
Autor:
Alison K. Gillingham, Sean Munro
Publikováno v:
Trends in Cell Biology. 26:399-408
The Golgi apparatus lies at the centre of the secretory pathway. It consists of a series of flattened compartments typically organised into a stack that, in mammals, is connected to additional stacks to form a Golgi ribbon. The Golgi is responsible f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d2bfd2ee35e1a9e348e7efbb01d77df
https://doi.org/10.1016/j.tcb.2016.02.005
https://doi.org/10.1016/j.tcb.2016.02.005