Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Alison Joly"'
Supplementary Data from Transforming Growth Factor-β Signaling–Deficient Fibroblasts Enhance Hepatocyte Growth Factor Signaling in Mammary Carcinoma Cells to Promote Scattering and Invasion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30f274faf8245c43cddc7b32e4153da1
https://doi.org/10.1158/1541-7786.22516647
https://doi.org/10.1158/1541-7786.22516647
Fibroblasts are major cellular components of the tumor microenvironment, regulating tumor cell behavior in part through secretion of extracellular matrix proteins, growth factors, and angiogenic factors. In previous studies, conditional deletion of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200e00dad35f6e8f502f4c15fe03397b
https://doi.org/10.1158/1541-7786.c.6541431
https://doi.org/10.1158/1541-7786.c.6541431
Supplementary Tables 1-2 from Enhanced Hepatocyte Growth Factor Signaling by Type II Transforming Growth Factor-β Receptor Knockout Fibroblasts Promotes Mammary Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc1d28069373e4c5396c587c1218cadd
https://doi.org/10.1158/0008-5472.22366470.v1
https://doi.org/10.1158/0008-5472.22366470.v1
Transforming growth factor-β (TGF-β) plays complex dual roles as an inhibitor and promoter of tumor progression. Although the influence of the stromal microenvironment on tumor progression is well recognized, little is known about the functions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02d958639613fef21b82ebc8e74a8c9b
https://doi.org/10.1158/0008-5472.c.6495150.v1
https://doi.org/10.1158/0008-5472.c.6495150.v1
Supplementary Methods from Enhanced Hepatocyte Growth Factor Signaling by Type II Transforming Growth Factor-β Receptor Knockout Fibroblasts Promotes Mammary Tumorigenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5ae410a2e8c59667c6785922a6faaa
https://doi.org/10.1158/0008-5472.22366473.v1
https://doi.org/10.1158/0008-5472.22366473.v1
Autor:
Fawn Qian, Justin Lesch, Yu-Chien Chou, Frauke Bentzien, Jenny Tan, A. Douglas Laird, Stefan Engst, Felix Chu, Kyoko Yamaguchi, F. Michael Yakes, Andrew You, Belinda Cancilla, Yongchang Shi, Jason Chen, Peiwen Yu, Lillian Lee, Jessica Orf, Alison Joly
Publikováno v:
Molecular Cancer Therapeutics. 10:2298-2308
The signaling pathway of the receptor tyrosine kinase MET and its ligand hepatocyte growth factor (HGF) is important for cell growth, survival, and motility and is functionally linked to the signaling pathway of VEGF, which is widely recognized as a
Publikováno v:
Molecular Cancer Research. 6:1521-1533
Fibroblasts are major cellular components of the tumor microenvironment, regulating tumor cell behavior in part through secretion of extracellular matrix proteins, growth factors, and angiogenic factors. In previous studies, conditional deletion of t
Autor:
Christopher Jaeger, A. Douglas Laird, Paul Keast, Dana T. Aftab, Steven Brian Gendreau, Felix Chu, Anushka De Costa, Peiwen Yu, Stephanie Meyer, Yongchang Shi, Frauke Bentzien, Belinda Cancilla, Wentao Zhang, Jean-Francois Martini, Richard Ventura, Lisa Jackman, Jeffery Lutman, Jason Chen, Alison Joly, Jing Wang, Kelly Engell, F. Michael Yakes
Publikováno v:
Clinical Cancer Research. 13:3713-3723
Purpose: Agents inhibiting the epidermal growth factor receptor (EGFR) have shown clinical benefit in a subset of non–small cell lung cancer patients expressing amplified or mutationally activated EGFR. However, responsive patients can relapse as a
Autor:
Ron G. Rosenfeld, Michelle M. Chen, Alison Joly, Junko Tsubaki, Youngman Oh, Stephen M. Twigg, Ho-Seong Kim, Vivian Hwa
Publikováno v:
Endocrinology. 143:1260-1269
Expansion of extracellular matrix with fibrosis occurs in many tissues, including skin, as part of the end-organ complications in diabetes. Advanced glycosylation end-products (AGEs) have been implicated as a pathogenic factor in diabetic tissue fibr
Publikováno v:
Atherosclerosis. 158:331-338
Macrophage infiltration, inflammatory processes and oxidatively modified low density lipoprotein (LDL) are known contributing factors in the formation of the atherosclerotic plaque. To determine whether a direct link might exist between these factors