Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alison J. Woods"'
Publikováno v:
Molecular and Cellular Biology. 25:3763-3773
We have previously identified poly(A)-binding protein 1 (PABP1) as a ligand for paxillin and shown that the paxillin-PABP1 complex undergoes nucleocytoplasmic shuttling. By targeting the paxillin-binding subdomain sequences in PABP1, we have generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ffcda16ede93a7956cf6576a6667d0
https://doi.org/10.1128/mcb.25.9.3763-3773.2005
https://doi.org/10.1128/mcb.25.9.3763-3773.2005
Publikováno v:
Molecular and Cellular Biology. 24:1505-1515
Protein kinase B (PKB)/Akt is known to promote cell migration, and this may contribute to the enhanced invasiveness of malignant cells. To elucidate potential mechanisms by which PKB/Akt promotes the migration phenotype, we have investigated its role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::216af0ef026ec4eb449e78a0cef2ced7
https://doi.org/10.1128/mcb.24.4.1505-1515.2004
https://doi.org/10.1128/mcb.24.4.1505-1515.2004
Publikováno v:
Journal of Biological Chemistry. 278:1975-1985
Kinases that associate with integrins are likely to mediate the assembly/disassembly of cell:matrix junctions during cell migration. Here we show that ERK1 associates with αvβ3 integrin following the addition of platelet-derived growth factor to se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a8cc2c25bab1a67e339007202092f5a
https://doi.org/10.1074/jbc.m208607200
https://doi.org/10.1074/jbc.m208607200
Autor:
Marnie S. Roberts, Hisataka Sabe, Simon J. Morley, Jim C. Norman, Yuichi Mazaki, Jyoti S. Choudhary, David R. Critchley, Alison J. Woods, Simon T. Barry
Publikováno v:
Journal of Biological Chemistry. 277:6428-6437
Using mass spectrometry we have identified proteins which co-immunoprecipitate with paxillin, an adaptor protein implicated in the integrin-mediated signaling pathways of cell motility. A major component of paxillin immunoprecipitates was poly(A)-bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c974af01d26a1d2b338f9bb4ef057c69
https://doi.org/10.1074/jbc.m109446200
https://doi.org/10.1074/jbc.m109446200
Publikováno v:
Current Biology. 11:1392-1402
It has been postulated that the regulation of integrin vesicular traffic facilitates cell migration by internalizing integrins at the rear of the cell and transporting them forward within vesicles for exocytosis at the leading edge to form new contac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6bd88accf5099dd43509245aad592c
https://doi.org/10.1016/s0960-9822(01)00442-0
https://doi.org/10.1016/s0960-9822(01)00442-0
Publikováno v:
The EMBO journal. 23(13)
To identify kinases that regulate integrin recycling, we have immunoprecipitated alphavbeta3 integrin from NIH 3T3 fibroblasts in the presence and absence of primaquine (a drug that inhibits receptor recycling and leads to accumulation of integrins i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a97b85a3560356d012aeb76cb484920c
https://pubmed.ncbi.nlm.nih.gov/15192707
https://pubmed.ncbi.nlm.nih.gov/15192707
Publikováno v:
The Journal of biological chemistry. 278(3)
Kinases that associate with integrins are likely to mediate the assembly/disassembly of cell:matrix junctions during cell migration. Here we show that ERK1 associates with alpha(v)beta(3) integrin following the addition of platelet-derived growth fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::640d9800d582f944c7a50b287f395d97
https://pubmed.ncbi.nlm.nih.gov/12393886
https://pubmed.ncbi.nlm.nih.gov/12393886