Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alison J. Winder"'
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1268:300-310
Melanin synthesis in the mouse involves the interaction of many pigmentation loci. Tyrosinase, the product of the albino (c) locus, catalyses the first step of the pathway. The brown (b) locus protein has significant homology to tyrosinase and contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3adfb7137941b0073585701db26dd579
https://doi.org/10.1016/0167-4889(95)00089-b
https://doi.org/10.1016/0167-4889(95)00089-b
Publikováno v:
Pigment Cell Research. 7:305-310
The mouse b locus controls black/brown coat coloration. Its product, the b-protein or TRP-1, has significant homology to tyrosinase, and this has led to suggestions that the b-protein is itself a melanogenic enzyme. In order to investigate its functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::956042ae7af56fc693edb9f8380a6ed9
https://doi.org/10.1111/j.1600-0749.1994.tb00632.x
https://doi.org/10.1111/j.1600-0749.1994.tb00632.x
Autor:
Alison J. Winder, Henry Harris
Publikováno v:
European Journal of Biochemistry. 198:317-326
New assays for the tyrosine hydroxylase and dopa oxidase activities of tyrosinase (EC 1.14.18.1) have been developed. The tyrosine hydroxylase assay uses L-[carboxy-14C]tyrosine as the substrate, 14CO2 is released from the products of the hydroxylati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0832c399f05d7c13b5e0fd23a0212d3
https://doi.org/10.1111/j.1432-1033.1991.tb16018.x
https://doi.org/10.1111/j.1432-1033.1991.tb16018.x
Autor:
Katsuhiko Tsukamoto, Timothy Brewington, Alison J. Winder, Brian Potterf, Vincent J. Hearing, Kazunori Urabe, Genji Imokawa, Takeshi Kobayashi
Publikováno v:
Pigment cell research. 7(4)
Tyrosinase-related protein 1 (TRP1) maps to the brown locus in mice. Although the specific function of TRP1 has been in dispute, mutations in its structural gene result in the formation of brown rather than black melanin. We have investigated the mel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185a9dc09c06115f2b69a4c3af9c7ebb
https://pubmed.ncbi.nlm.nih.gov/7855068
https://pubmed.ncbi.nlm.nih.gov/7855068
Autor:
Alison J. Winder
Publikováno v:
Journal of biochemical and biophysical methods. 28(3)
A stopped spectrophotometric assay for the dopa oxidase activity of tyrosinase has been developed to enable large numbers of samples to be screened very rapidly. The assay measures the pink pigment formed by the reaction of Besthorn's hydrazone (3-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f60faee96953ee25be456016763b0d2
https://pubmed.ncbi.nlm.nih.gov/8064113
https://pubmed.ncbi.nlm.nih.gov/8064113
Publikováno v:
Journal of cell science. 106
Many genes mapping to pigmentation loci are involved in the regulation of melanin synthesis in the mouse. The brown (b) locus controls black/brown coat coloration, and its product has significant homology to the key melanogenic enzyme tyrosinase. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dba74998b5d67d4fca7a023e0648e02
https://pubmed.ncbi.nlm.nih.gov/8270621
https://pubmed.ncbi.nlm.nih.gov/8270621
Publikováno v:
Journal of cell science. 104
Recent advances in the study of the molecular biology of mouse pigmentation have led to the discovery of a family of proteins involved in the control of melanin synthesis. It has been confirmed that the product of the mouse c (albino) locus is the ke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5747f19f6860da070a94171084fa99e
https://pubmed.ncbi.nlm.nih.gov/8505373
https://pubmed.ncbi.nlm.nih.gov/8505373
Autor:
Alison J. Winder
Publikováno v:
Biochemical and biophysical research communications. 178(2)
3T3 Swiss mouse fibroblast cell lines expressing tyrosinase, the critical enzyme in melanin synthesis, have been established by co-transfection of a mouse tyrosinase cDNA and a G418-resistance gene. Of sixty-three clones isolated, four are brown in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14fad744ff76c8ea0fd688c4e304f2a
https://pubmed.ncbi.nlm.nih.gov/1907137
https://pubmed.ncbi.nlm.nih.gov/1907137