Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alison J. Powell"'
Autor:
Alison Paul, Omar T. Mansour, Bruce Caterson, Stephen Hopkins, Peter C. Griffiths, Claire Hughes, Craig James, Alison J. Powell
Publikováno v:
Journal of Drug Targeting. 25:919-926
open access article The ability of a polymer therapeutic to access the appropriate subcellular location is crucial to its efficacy and is defined to a large part by the many and complex cellular biological and biochemical barriers such that a constru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816f94ebc95d3764e2c526d0ac3549c3
https://doi.org/10.1080/1061186x.2017.1378660
https://doi.org/10.1080/1061186x.2017.1378660
Publikováno v:
Arthritis & Rheumatism. 56:3010-3019
Objective: The major proteases responsible for aggrecan turnover in articular cartilage are the aggrecanases (ADAMTS-4 and ADAMTS-5). Although several studies have demonstrated C-terminal truncation of these aggrecanases, the mechanism and importance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edfab6debf1115749f5e6cca53a8ab6b
https://doi.org/10.1002/art.22818
https://doi.org/10.1002/art.22818
Autor:
Elaine Lesley Ferguson, Simon C. W. Richardson, Kerri-Lee Wallom, M. Davies, Robert C. Piper, Ruth Duncan, Simon P. E. Deacon, Alison J. Powell
Macromolecular therapeutics and nano-sized drug delivery systems often require localisation to specific intracellular compartments. In particular, efficient endosomal escape, retrograde trafficking, or late endocytic/lysosomal activation are often pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e119fc31c4fd249b3872607cfaa5d3
https://europepmc.org/articles/PMC6661902/
https://europepmc.org/articles/PMC6661902/
