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pro vyhledávání: '"Alison J. Kim"'
Autor:
James M. Lindberg, Timothy E. Newhook, Sara J. Adair, Dustin M. Walters, Alison J. Kim, Edward B. Stelow, J. Thomas Parsons, Todd W. Bauer
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 7, Pp 562-571 (2014)
Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations and epidermal growth factor receptor (EGFR) family signaling are drivers of tumorigenesis in pancreatic ductal adenocarcinoma (PDAC). Previous studies have demonstrated that combinatorial tr
Externí odkaz:
https://doaj.org/article/30740983972940199a2365ff81e3d51a
Autor:
Edward B. Stelow, Todd W. Bauer, Sara J. Adair, Dustin M. Walters, Timothy E. Newhook, J. Thomas Parsons, Alison J. Kim, James M. Lindberg
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 16, Iss 7, Pp 562-571 (2014)
Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations and epidermal growth factor receptor (EGFR) family signaling are drivers of tumorigenesis in pancreatic ductal adenocarcinoma (PDAC). Previous studies have demonstrated that combinatorial tr
Autor:
J. Thomas Parsons, Osama E. Rahma, Alison J. Kim, James M. Lindberg, Timothy E. Newhook, Sara J. Adair, Edward B. Stelow, Todd W. Bauer
Publikováno v:
Annals of surgical oncology. 23(6)
Most patients with pancreatic ductal adenocarcinoma (PDAC) die within 5 years following resection plus adjuvant gemcitabine (Gem) from outgrowth of occult metastases. We hypothesized that inhibition of the KRAS pathway with the MEK inhibitor trametin
Autor:
Sharyn A. Endow, Alison J. Kim
Publikováno v:
Journal of cell science.
The kinesin tree was built from a sequence alignment of 144 kinesin motor domains from 31 species using the heuristic search method of PAUP v. 4.0b4a ( [Swofford, 1998][1]), a maximum parsimony program, and random stepwise addition and ‘tree-bisect
Autor:
James M. Lindberg, Timothy E. Newhook, Sara J. Adair, Alison J. Kim, J. Thomas Parsons, Todd W. Bauer
Publikováno v:
Journal of Clinical Oncology. 31:190-190
190 Background: Aberrant MAPK and EGFR family signaling are key drivers of pancreatic ductal adenocarcinoma(PDAC). We hypothesized that combination trametinib(MEK1/2 inhibitor), panitumumab(EGFR inhibitor) and trastuzumab(Her2 inhibitor) would more e