Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alison J. Hurst"'
Publikováno v:
Public health. 182
Objective To examine the effectiveness of interventions using the World Health Organization Health Promoting Schools (HPSs) framework approach in increasing physical activity (PA) and improving the diet of 11–18-year-olds. Study design A systematic
Autor:
Emma Ryan, Louise Crathorne, Adam Streeter, Katrina Wyatt, Sarah Dean, Alison J. Hurst, Richard J. Siegert, Rod S Taylor, Stuart Logan, Colin Green, Camilla McHugh, Charles Abraham, Melvyn Hillsdon, Richard Tomlinson, Jenny Lloyd, Chris Krägeloh, Siobhan Creanor, Virginia Pearson, Lisa Price
Publikováno v:
Public Health Research, Vol 6, Iss 1 (2018)
BackgroundApproximately one-third of children in England leave primary school overweight or obese. There is little evidence of effective obesity prevention programmes for children in this age group.ObjectiveTo determine the effectiveness and cost-eff
Publikováno v:
Journal of Children's Services. 9:58-74
Purpose – Despite an increasing policy focus, routine outcome monitoring (ROM) is not common practice in UK children's services. This paper aims to examine whether it is feasible and valid to use measures from ROM of evidence-based parenting progra
Autor:
Jenny Lloyd, Richard Tomlinson, Colin Green, Sarah Dean, Siobhan Creanor, Emma Ryan, Melvyn Hillsdon, Charles Abraham, Katrina Wyatt, Alison J. Hurst, Stuart Logan, Rod S Taylor, Wendy Daurge, Virginia Pearson, Lisa Price
Publikováno v:
BMC Public Health
BMC Public Health, Vol 17, Iss 1, Pp 1-14 (2017)
BMC Public Health, Vol 17, Iss 1, Pp 1-14 (2017)
Background We have developed a healthy lifestyles programme (HeLP) for primary school aged children (9–10 years), currently being evaluated in a definitive cluster randomised controlled trial. This paper descriptively presents the baseline characte
A common variant of the p16INK4a genetic region is associated with physical function in older people
Autor:
Anna Maria Corsi, Paul D.P. Pharoah, Kay-Tee Khaw, Andrew T. Hattersley, Timothy M. Frayling, Luigi Ferrucci, Stefania Bandinelli, Anna Murray, David Melzer, Robert B. Wallace, Honglin Song, Jack M. Guralnik, Paul G. Surtees, Lorna W. Harries, Alison J. Hurst, Robert Luben
Publikováno v:
Mechanisms of Ageing and Development. 128:370-377
p16(INK4a) is active in cell senescence, ageing and tumor suppression. Deletion of the small p16(INK4a)/ARF/p15(INK4b) region occurs in many cancers. We screened 25 common polymorphisms across the region and three related genes for associations with
Publikováno v:
Scopus-Elsevier
The genetics of aging has seen extraordinary progress over the last few decades, with animal models suggesting key roles for a number of metabolic pathways. However, humans outlive laboratory models many times over, and only evidence from humans can
Publikováno v:
Healthplace. 18(3)
This systematic review considers current literature on the association between childhood overweight and obesity and the primary school built environment. Bibliographic databases from the fields of medicine, social science, exercise science and educat
Autor:
Luigi Ferrucci, J. Raphael Gibbs, Michael N. Weedon, Tamara B. Harris, Alison J. Hurst, William Henley, Annamaria Corsi, Vijay Panicker, Colin M. Dayan, Amanda J. Bennett, Nicole Washecka, Kara Stevens, Stefania Bandinelli, Jack M. Guralnik, Giuseppe Paolisso, Sampath Arepalli, Marjo-Riitta Järvelin, Ian Rafferty, Joyce van de Leemput, John R. B. Perry, Sonja W. Scholz, Mark I. McCarthy, Gregory J. Tranah, Hana Lango, Javier Simón-Sánchez, Rongling Li, Aimo Ruokonen, Andrew B. Singleton, Anne B. Newman, Timothy M. Frayling, Fulvio Lauretani, Dena G. Hernandez, Neil Rice, Anna Murray, David Melzer, Sajjad Rafiq, Angela Britton
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 4, Iss 5, p e1000072 (2008)
PLoS Genetics, Vol 4, Iss 5, p e1000072 (2008)
There is considerable evidence that human genetic variation influences gene expression. Genome-wide studies have revealed that mRNA levels are associated with genetic variation in or close to the gene coding for those mRNA transcripts – cis effects
Autor:
Luigi Ferrucci, Kara Stevens, Annamaria Corsi, William Henley, Sajjad Rafiq, Alison J. Hurst, Anna Murray, Michael N. Weedon, David Melzer, J. M. Guralnik, Timothy M. Frayling, Stefania Bandinelli
Interleukin-6 (IL-6) is a key inflammatory cytokine, signalling to most tissues by binding to a soluble IL-6 receptor (sIL-6r), making a complex with gp130. We used 1273 subjects (mean age 68 years) from the InCHIANTI Italian cohort to study common v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b50a47ad8450ea6d67e2d1494558cd26
https://europepmc.org/articles/PMC2668154/
https://europepmc.org/articles/PMC2668154/
Autor:
Luigi Ferrucci, Sajjad Rafiq, Stefania Bandinelli, Timothy M. Frayling, Jack M. Guralnik, Michael N. Weedon, Alison J. Hurst, Anna Murray, David Melzer, William Henley, Anna Maria Corsi, Robert B. Wallace
Background—The proinflammatory cytokine interleukin-18 (IL-18) is associated with major disabling conditions, although whether as byproduct or driver is unclear. The role of common variation in the IL-18 gene on serum concentrations and functioning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74cb12d5892a4bc57fa0590e84d32dc8
https://europepmc.org/articles/PMC2669299/
https://europepmc.org/articles/PMC2669299/