Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Alison J Thomson"'
Autor:
Lucas Lefevre, Kim M. Summers, Tom Burdon, Alison J. Thomson, Kyle R. Upton, Gemma M. Davis, Rocio Rojo, Kristin A. Sauter, Neil A. Mabbott, Joana Alves, Lee B. Smith, Yi Ting Tsai, Kathleen Grabert, Robert Wallace, Anna Raper, Tim Regan, David A. Hume, Sara Clohisey, Pedro Piccardo, Stephen Meek, Zofia M. Lisowski, Michael Cheeseman, Clare Pridans, Stephen J. Bush, Deborah Brown, Linda Sutherland
Publikováno v:
The Journal of Immunology. 202:3334-3335
In the analysis of gene expression in the brain, the sample labels for the pituitary gland and olfactory bulb were reversed. As a consequence, the clusters in Fig. 10B were mislabeled. A corrected version of Fig. 10 is shown below, along with the cor
Autor:
Tom Burdon, C. Bruce A. Whitelaw, Chiara Sartori, Alex I DiDomenico, Elspeth Milne, Simon G. Lillico, Alison J. Thomson
Publikováno v:
Cellular Reprogramming. 14:8-19
Pluripotential stem cells from livestock offer an exciting prospect for the biotechnology industry. Applying strategies established for the derivation of murine induced pluripotential stem cells (iPSCs), we have isolated ovine iPSCs that can give ris
Publikováno v:
Cloning and Stem Cells. 10:217-230
Genetic modification of human embryonic stem cells (hESCs) will be an essential tool to allow full exploitation of these cells in regenerative medicine and in the study of hESC biology. Here we report multiple sequential modifications of an endogenou
Autor:
Alison J. Thomson, Joseph R. Smith-Arica, Jim McWhir, Ray Ansell, John A. Chiorini, Beverly L. Davidson
Publikováno v:
Cloning and Stem Cells. 5:51-62
Human and mouse embryonic stem (ES) cells have the capacity to differentiate into derivatives of all three germ layers, suggesting novel therapies for degenerative, metabolic, and traumatic disorders. ES-based regenerative medicine will be further ad
Autor:
Alison J. Thomson, Richard Talbot, Alexandra Bogerman, Alan Archibald, Chiara Sartori, Hadrien Pierart, Alison Downing, Tom Burdon, Stephen Meek, Tom C. Freeman, Edward Mountjoy, Linda Sutherland, C. Bruce A. Whitelaw, Helen Murray
Publikováno v:
Thomson, A J, Pierart, H, Meek, S, Bogerman, A, Sutherland, L, Murray, H, Mountjoy, E, Downing, A, Talbot, R, Sartori, C, Whitelaw, C B A, Freeman, T C, Archibald, A L & Burdon, T 2012, ' Reprogramming Pig Fetal Fibroblasts Reveals a Functional LIF Signaling Pathway ', Cellular Reprogramming, vol. 14, no. 2, pp. 112-122 . https://doi.org/10.1089/cell.2011.0078
Distinct signaling pathways are reported to maintain pluripotency in embryo-derived stem cells. Mouse embryonic stem cells (ESCs) respond to leukemia inhibitory factor (LIF) and bone morphogenetic protein (BMP)-mediated activity, whereas human ESCs d
Autor:
Anthony H.V. Schapira, Fatima Cavaleri, Michael J. Devine, Jan-Willem Taanman, Alison J. Thomson, John Hardy, Tom Burdon, Petr Vodicka, Katrina Gwinn, Tilo Kunath, Nicola J. Drummond, Masumi Nagano, Patrick A. Lewis, Mina Ryten, Henry Houlden
Publikováno v:
Devine, M J, Ryten, M, Vodicka, P, Thomson, A J, Burdon, T, Houlden, H, Cavaleri, F, Nagano, M, Drummond, N J, Taanman, J-W, Schapira, A H, Gwinn, K, Hardy, J, Lewis, P A & Kunath, T 2011, ' Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus ', Nature Communications, vol. 2, no. n/a, 440 . https://doi.org/10.1038/ncomms1453
Nature Communications
Nature Communications
A major barrier to research on Parkinson's disease is inaccessibility of diseased tissue for study. One solution is to derive induced pluripotent stem cells from patients and differentiate them into neurons affected by disease. Triplication of SNCA,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e522169e59b291c2f34af6f954cd265e
https://www.pure.ed.ac.uk/ws/files/8392142/NC_2011_Kunath.pdf
https://www.pure.ed.ac.uk/ws/files/8392142/NC_2011_Kunath.pdf
Autor:
Alison J. Thomson, John J. Mullins, Tom Burdon, Mia Buehr, Stephen Meek, Andrew J.H. Smith, Linda Sutherland
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14225 (2010)
Meek, S, Buehr, M, Sutherland, L, Thomson, A, Mullins, J J, Smith, A & Burdon, T 2010, ' Efficient Gene Targeting by Homologous Recombination in Rat Embryonic Stem Cells ', PLoS ONE, vol. 5, no. 12, e14225, pp.-. https://doi.org/10.1371/journal.pone.0014225
PLoS ONE
Meek, S, Buehr, M, Sutherland, L, Thomson, A, Mullins, J J, Smith, A & Burdon, T 2010, ' Efficient Gene Targeting by Homologous Recombination in Rat Embryonic Stem Cells ', PLoS ONE, vol. 5, no. 12, e14225, pp.-. https://doi.org/10.1371/journal.pone.0014225
PLoS ONE
The rat is the preferred experimental animal in many biological studies. With the recent derivation of authentic rat embryonic stem (ES) cells it is now feasible to apply state-of-the art genetic engineering in this species using homologous recombina
Autor:
Virginie Sottile, Nusrat Khan, Ioannis Christodoulou, Alison J. Thomson, S.N. Racey, S Collishaw, Brendon Noble, J. L. Tremoleda, Jim McWhir, Nicholas R. Forsyth, B.J. Tye, Davina Wojtacha, A.H.W.R. Simpson
Publikováno v:
Cloning and stem cells. 10(1)
Although the use of embryonic stem cells in the assisted repair of musculoskeletal tissues holds promise, a direct comparison of this cell source with adult marrow-derived stem cells has not been undertaken. Here we have compared the osteogenic diffe
Publikováno v:
Advances in experimental medicine and biology. 534