Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Alison J Sinclair"'
Autor:
Lenka Skalska, Robert E White, Gillian A Parker, Ernest Turro, Alison J Sinclair, Kostas Paschos, Martin J Allday
Publikováno v:
PLoS Pathogens, Vol 9, Iss 2, p e1003187 (2013)
To explore the role of p16(INK4a) as an intrinsic barrier to B cell transformation by EBV, we transformed primary B cells from an individual homozygous for a deletion in the CDKN2A locus encoding p16(INK4a) and p14(ARF). Using recombinant EBV-BAC vir
Externí odkaz:
https://doaj.org/article/28b56d54882a42acada95ed3eb0c789a
Autor:
Kirsty Flower, David Thomas, James Heather, Sharada Ramasubramanyan, Susan Jones, Alison J Sinclair
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25922 (2011)
Epstein-Barr virus (EBV) encoded transcription factor Zta (BZLF1, ZEBRA, EB1) is the prototype of a class of transcription factor (including C/EBPalpha) that interact with CpG-containing DNA response elements in a methylation-dependent manner. The EB
Externí odkaz:
https://doaj.org/article/21ccba172c904c5889266216e62085a7
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9443 (2010)
Epstein Barr virus (EBV) infects the majority of the human population, causing fatal diseases in a small proportion in conjunction with environmental factors. Following primary infection, EBV remains latent in the memory B cell population for life. R
Externí odkaz:
https://doaj.org/article/9faff517e410496abb379e8a5302f307
Publikováno v:
PLoS Pathogens, Vol 4, Iss 3, p e1000005 (2008)
Epstein-Barr virus (EBV) causes infectious mononucleosis and is associated with various malignancies, including Burkitt's lymphoma and nasopharyngeal carcinoma. Like all herpesviruses, the EBV life cycle alternates between latency and lytic replicati
Externí odkaz:
https://doaj.org/article/c18ab1e0c2d04ee98bcffc808eada0b4
Autor:
Alison J. Sinclair
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
DNA methylation at CpG motifs provides an epigenetic route to regulate gene expression. In general, an inverse correlation between DNA hypermethylation at CpG motifs and gene expression is observed. Epstein Barr-virus (EBV) infects people and the EBV
Externí odkaz:
https://doaj.org/article/f8d3d5721b734b85a0b9db6063071932
Publikováno v:
Access Microbiology
Epstein–Barr virus (EBV) is present in a state of latency in infected memory B-cells and EBV-associated lymphoid and epithelial cancers. Cell stimulation or differentiation of infected B-cells and epithelial cells induces reactivation to the lytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b727aff1c5a12f35151df304e6b641
https://doi.org/10.1099/acmi.0.000282
https://doi.org/10.1099/acmi.0.000282
Publikováno v:
Cancers, Vol 13, Iss 819, p 819 (2021)
Cancers
Cancers
Simple Summary Epstein–Barr virus (EBV) is a virus that infects people and then remains within their bodies for life. Almost everyone is infected with EBV by the time they are an adult. EBV is called a cancer virus because it causes some cancers of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72261bd83dae3a6765efa0979b4bdf96
http://sro.sussex.ac.uk/id/eprint/101595/1/cancers-13-00819.pdf
http://sro.sussex.ac.uk/id/eprint/101595/1/cancers-13-00819.pdf
Autor:
Rajaei Almohammed, Alison J. Sinclair, Yaqi Zhou, Steve M. M. Sweet, Kay Osborn, Kate J. Heesom
Publikováno v:
J Virol
Zhou, Y, Heesom, K, Osborn, K, Almohammad, R, Sweet, S M & Sinclair, A J 2020, ' Identifying the Cellular Interactome of Epstein-Barr Virus Lytic Regulator Zta Reveals Cellular Targets Contributing to Viral Replication ', Journal of Virology . https://doi.org/10.1128/JVI.00927-19
Zhou, Y, Heesom, K, Osborn, K, Almohammad, R, Sweet, S M & Sinclair, A J 2020, ' Identifying the Cellular Interactome of Epstein-Barr Virus Lytic Regulator Zta Reveals Cellular Targets Contributing to Viral Replication ', Journal of Virology . https://doi.org/10.1128/JVI.00927-19
The human gamma herpesvirus Epstein-Barr virus (EBV; HHV4), infects most adults and is an important contributor to the development of many types of lymphoid and epithelial cancers. Essential contributions of viral genes to viral replication are known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369fe770d4262e8111bfabb3648befa8
https://europepmc.org/articles/PMC7000981/
https://europepmc.org/articles/PMC7000981/
Autor:
Rajaei, Almohammed, Kay, Osborn, Sharada, Ramasubramanyan, Ijiel Barak Naranjo, Perez-Fernandez, Anja, Godfrey, Erika J, Mancini, Alison J, Sinclair
Publikováno v:
The Journal of General Virology
The human gamma herpes virus Epstein–Barr virus (EBV) exploits multiple routes to evade the cellular immune response. During the EBV lytic replication cycle, viral proteins are expressed that provide excellent targets for recognition by cytotoxic T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4d7c2b6999cb0ecf81dac6ef5647d6a5
https://pubmed.ncbi.nlm.nih.gov/29580369
https://pubmed.ncbi.nlm.nih.gov/29580369
Publikováno v:
Journal of Clinical Microbiology. 51:2303-2310
Standard culture methods for diagnosis of Streptococcus pneumoniae pneumonia take at least 24 h. The BinaxNOW urine-based test for S. pneumoniae (BinaxNOW-SP) takes only 15 min to conduct, potentially enabling earlier diagnosis and targeted treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d7d6fcb59ebdc4c779d2017a8722d6
https://doi.org/10.1128/jcm.00137-13
https://doi.org/10.1128/jcm.00137-13