Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Alison J Reeve"'
Autor:
Jane P. Hughes, Lauriane Ulmann, François Rassendren, Severine Chaumont, Alison J Reeve, Paula J. Green, Jon P. Hatcher, Iain P. Chessell, G. Buell, François Conquet
Publikováno v:
The Journal of Neuroscience. 28:11263-11268
ATP is a known mediator of inflammatory and neuropathic pain. However, the mechanisms by which specific purinergic receptors contribute to chronic pain states are still poorly characterized. Here, we demonstrate that in response to peripheral nerve i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6839cc6a2457983b8d3cebd21a2af3ae
https://doi.org/10.1523/jneurosci.2308-08.2008
https://doi.org/10.1523/jneurosci.2308-08.2008
Autor:
Simon T. Bate, Sue D. Collins, Jo C Martindale, Caroline J Sharp, Scott G. Summerfield, Alison J Reeve, Iain P. Chessell, Becky Sargent
Publikováno v:
British Journal of Pharmacology. 148:845-852
1. Two P2X(3)/P2X(2/3) receptor antagonists with different potencies were profiled electrophysiologically in a rat model of nerve injury. 2. A-317491 has poor CNS penetrance (blood:brain, 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cbd553c9c6e5cab1bc19d1432d84513
https://doi.org/10.1038/sj.bjp.0706790
https://doi.org/10.1038/sj.bjp.0706790
Publikováno v:
Journal of Biological Chemistry. 279:17165-17172
The vanilloid receptor 1 (VR1 or TRPV1) ion channel is activated by noxious heat, low pH and by a variety of vanilloid-related compounds. The antagonist, capsazepine is more effective at inhibiting the human TRPV1 response to pH 5.5 than the rat TRPV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4acc847c566d2ae40b708a700153de78
https://doi.org/10.1074/jbc.m313328200
https://doi.org/10.1074/jbc.m313328200
Autor:
A Davis, Glen Wotherspoon, Katharine Walker, P Schmid, Alison J. Reeve, Janet Winter, Laszlo Urban, Fabrizio Gasparini, M Bowes, Rainer Kuhn
Publikováno v:
Neuropharmacology. 40:10-19
Previous studies have demonstrated that the metabotropic glutamate receptor subtype 5 (mGlu5 receptor) is expressed in the cell bodies of rat primary afferent neurones. We have further investigated the function and expression of mGlu5 receptors in pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f9eabf5fb08a341413f51b032a1045b
https://doi.org/10.1016/s0028-3908(00)00114-3
https://doi.org/10.1016/s0028-3908(00)00114-3
Publikováno v:
CNS Drugs. 13:77-85
Substantial evidence exists for the physiological role of adenosine in the modulation of primary afferent transmission. Since the first description of the anti-nociceptive effects of adenosine, there has been considerable interest in the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e97e8d45891b3874ce0e92508830a0f
https://doi.org/10.2165/00023210-200013020-00001
https://doi.org/10.2165/00023210-200013020-00001
Autor:
Anthony H. Dickenson, Alison J. Reeve
Publikováno v:
Analgesia. 1:671-674
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d319f3787b8c2b5af0efe0e447907c1b
https://doi.org/10.3727/107156995819562907
https://doi.org/10.3727/107156995819562907
Autor:
Daniel S. McQueen, Alison J Reeve, Susan M. Bond, Iain P. Chessell, Simon T. Bate, Iain T. Strickland, Nicola J. Barton, Harry M. Brash, Alex W. Wilson
Publikováno v:
Journal of neuroscience methods. 163(1)
Chronic joint pain affects physical well being and can lead to severe psychological and social problems, therefore successful long-term management is highly sought-after. No current behavioural measures of pain used in pre-clinical models mimic the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66dbb3cea7d59aedcea0bc861015f139
https://pubmed.ncbi.nlm.nih.gov/17383008
https://pubmed.ncbi.nlm.nih.gov/17383008
Publikováno v:
Pain. 133(1-3)
Intra-articular injection of Freund's complete adjuvant (FCA) into the rat knee joint produces a swelling of the joint and long lasting hypersensitivity. In this study we have used this model and in vivo electrophysiology to investigate the time cour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2886f2175cde7e1389d17480d38e1628
https://pubmed.ncbi.nlm.nih.gov/17467170
https://pubmed.ncbi.nlm.nih.gov/17467170
Autor:
Caroline J, Sharp, Alison J, Reeve, Sue D, Collins, Jo C, Martindale, Scott G, Summerfield, Becky S, Sargent, Simon T, Bate, Iain P, Chessell
Publikováno v:
British journal of pharmacology. 148(6)
1. Two P2X(3)/P2X(2/3) receptor antagonists with different potencies were profiled electrophysiologically in a rat model of nerve injury. 2. A-317491 has poor CNS penetrance (blood:brain, 1:0.05), and was therefore administered intravenously in chron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d72ebccdbead63607d7bec3ffaff0a48
https://pubmed.ncbi.nlm.nih.gov/16770326
https://pubmed.ncbi.nlm.nih.gov/16770326
Autor:
Alison J. Reeve, Stuart Bevan
Publisher Summary This chapter focuses on the vanilloid receptor 1 (VR1), which is considered as an integrator of noxius and inflammatory stimuli. The relationships between the various modalities sensed by polymodal nociceptors and the underlying tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25389c3372293e56248cdcfbbed2d8d5
https://doi.org/10.1016/s1569-2558(03)32014-4
https://doi.org/10.1016/s1569-2558(03)32014-4
