Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Alison J Johnson"'
Autor:
Tong-yuan Yang, Manuela Braun, Wibke Lembke, Fraser McBlane, John Kamerud, Stephen DeWall, Edit Tarcsa, Xiaodong Fang, Lena Hofer, Uma Kavita, Vijay V. Upreti, Swati Gupta, LiNa Loo, Alison J. Johnson, Rakesh Kantilal Chandode, Kay-Gunnar Stubenrauch, Maya Vinzing, Cindy Q. Xia, Vibha Jawa
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 471-494 (2022)
Immunogenicity has imposed a challenge to efficacy and safety evaluation of adeno-associated virus (AAV) vector-based gene therapies. Mild to severe adverse events observed in clinical development have been implicated with host immune responses again
Externí odkaz:
https://doaj.org/article/1b85bb2274f44631a3d3b829f5704b0f
Autor:
Robert S. Lanciotti, Olga L. Kosoy, Janeen J. Laven, Jason O. Velez, Amy J. Lambert, Alison J. Johnson, Stephanie M. Stanfield, Mark R. Duffy
Publikováno v:
Emerging Infectious Diseases, Vol 14, Iss 8, Pp 1232-1239 (2008)
Zika virus (ZIKV) is a mosquito-borne flavivirus first isolated in Uganda from a sentinel monkey in 1947. Mosquito and sentinel animal surveillance studies have demonstrated that ZIKV is endemic to Africa and Southeast Asia, yet reported human cases
Externí odkaz:
https://doaj.org/article/5192c684fed642d9b46e0c033583102d
Autor:
Grégoire Lauvau, John Chan, Nazanin Khajoueinejad, Christopher T. Johndrow, Michael F. Goldberg, William R. Jacobs, Noemi Alejandra Saavedra-Avila, Steven A. Porcelli, Jiayong Xu, Betsy C. Herold, Tony W. Ng, Alison J. Johnson, Shajo Kunnath-Velayudhan, John Kim, Pooja Arora, Christopher Petro, Neeraj K. Saini
Publikováno v:
ImmunoHorizons. 3:161-171
During Ag priming, naive CD4+ T cells differentiate into subsets with distinct patterns of cytokine expression that dictate to a major extent their functional roles in immune responses. We identified a subset of CD4+ T cells defined by secretion of I
Autor:
Manjunatha M Venkataswamy, Tony W Ng, Shalu S Kharkwal, Leandro J Carreño, Alison J Johnson, Shajo Kunnath-Velayudhan, Zheng Liu, Robert Bittman, Peter J Jervis, Liam R Cox, Gurdyal S Besra, Xiangshu Wen, Weiming Yuan, Moriya Tsuji, Xiangming Li, David D Ho, John Chan, Sunhee Lee, Richard Frothingham, Barton F Haynes, Michael W Panas, Geoffrey O Gillard, Jaimie D Sixsmith, Birgit Korioth-Schmitz, Joern E Schmitz, Michelle H Larsen, William R Jacobs, Steven A Porcelli
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108383 (2014)
Recombinant Mycobacterium bovis bacillus Calmette-Guèrin (rBCG) has been explored as a vector for vaccines against HIV because of its ability to induce long lasting humoral and cell mediated immune responses. To maximize the potential for rBCG vacci
Externí odkaz:
https://doaj.org/article/90e45a31ded54c5cbca2c3231d0f0e54
Autor:
Ulrich D. Kadolsky, Daniel H. Kaplan, Alison J. Johnson, Tony W. Ng, Andrew J. Yates, Steven A. Porcelli, Grégoire Lauvau, Shajo Kunnath-Velayudhan, G. H. Gossel, William R. Jacobs, John Chan, Christopher T. Johndrow, Michael F. Goldberg
Publikováno v:
The Journal of Immunology. 201:3604-3616
Effective subunit vaccines require the incorporation of adjuvants that stimulate cells of the innate immune system to generate protective adaptive immune responses. Pattern recognition receptor agonists are a growing class of potential adjuvants that
Autor:
Steven A. Porcelli, William R. Jacobs, Jiayong Xu, John Chan, Neeraj K. Saini, Michael F. Goldberg, Alison J. Johnson, Tony W. Ng, Christopher T. Johndrow, Shajo Kunnath-Velayudhan
Publikováno v:
The Journal of Immunology. 199:2596-2606
Analysis of Ag-specific CD4+ T cells in mycobacterial infections at the transcriptome level is informative but technically challenging. Although several methods exist for identifying Ag-specific T cells, including intracellular cytokine staining, cel
Autor:
Shajo, Kunnath-Velayudhan, Michael F, Goldberg, Neeraj K, Saini, Tony W, Ng, Pooja, Arora, Christopher T, Johndrow, Noemi Alejandra, Saavedra-Avila, Alison J, Johnson, Jiayong, Xu, John, Kim, Nazanin, Khajoueinejad, Christopher D, Petro, Betsy C, Herold, Gregoire, Lauvau, John, Chan, William R, Jacobs, Steven A, Porcelli
Publikováno v:
ImmunoHorizons
During Ag priming, naive CD4+ T cells differentiate into subsets with distinct patterns of cytokine expression that dictate to a major extent their functional roles in immune responses. We identified a subset of CD4+ T cells defined by secretion of I
Autor:
Jiayong Xu, Scott J. Garforth, Steven A. Porcelli, Cecilia S. Lindestam Arlehamn, Steven C. Almo, William R. Jacobs, Steven C. Kennedy, Alessandro Sette, Sushma Bharrhan, John Chan, Alison J. Johnson
Publikováno v:
Infection and Immunity. 86
Mycobacterium tuberculosis remains a threat to global health, and a more efficacious vaccine is needed to prevent disease caused by M. tuberculosis We previously reported that the mycobacterial ribosome is a major target of CD4+ T cells in mice immun
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1808
Enzyme-linked immunospot (ELISPOT) is an assay used to detect secretion of cytokines from immune cells. The resolution and sensitivity of ELISPOT allow for the detection of rare T cell specificities and small quantities of molecules produced by indiv
Autor:
Steven C, Kennedy, Alison J, Johnson, Sushma, Bharrhan, Cecilia S, Lindestam Arlehamn, Jiayong, Xu, Scott J, Garforth, John, Chan, William R, Jacobs, Alessandro, Sette, Steven C, Almo, Steven A, Porcelli
Publikováno v:
Infection and immunity. 86(9)
Mycobacterium tuberculosis remains a threat to global health, and a more efficacious vaccine is needed to prevent disease caused by M. tuberculosis. We previously reported that the mycobacterial ribosome is a major target of CD4(+) T cells in mice im