Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Alison J, Forhead"'
Autor:
Rhian Young, Dominika Lewandowska, Emily Long, F. B. Peter Wooding, Miles J. De Blasio, Katie L. Davies, Emily J. Camm, Per T. Sangild, Abigail L. Fowden, Alison J. Forhead
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Growth and maturation of the fetal gastrointestinal tract near term prepares the offspring for the onset of enteral nutrition at birth. Structural and functional changes are regulated by the prepartum rise in cortisol in the fetal circulation, althou
Externí odkaz:
https://doaj.org/article/717a019394af4856824527e8c3ae32f5
Autor:
Katie L. Davies, Danielle J. Smith, Tatiana El-Bacha, Peter F. P. Wooding, Alison J. Forhead, Andrew J. Murray, Abigail L. Fowden, Emily J. Camm
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 768 (2022)
In adults, glucocorticoids are stress hormones that act, partly, through actions on mitochondrial oxidative phosphorylation (OXPHOS) to increase energy availability. Before birth, glucocorticoids are primarily maturational signals that prepare the fe
Externí odkaz:
https://doaj.org/article/a50548faa67442c3a0527046f26665eb
Autor:
Katie L. Davies, Alison J. Forhead, Emily J. Camm, Owen R. Vaughan, Abigail L. Fowden, D J Smith, Andrew J. Murray
Publikováno v:
The Journal of Endocrinology
In adults, glucocorticoids act to match the supply and demand for energy during physiological challenges, partly through actions on tissue mitochondrial oxidative phosphorylation (OXPHOS) capacity. However, little is known about the role of the natur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc33634b0c6a9b658c9a5a905bcdf2d
https://doi.org/10.1530/joe-21-0171
https://doi.org/10.1530/joe-21-0171
Autor:
Dominique Blache, Stuart A. Lanham, Abigail L. Fowden, Alison J. Forhead, Richard O.C. Oreffo
Publikováno v:
The Journal of Endocrinology
Hormones have an important role in the regulation of fetal growth and development, especially in response to nutrient availability in utero. Using micro-CT and an electromagnetic three-point bend test, this study examined the effect of pancreas remov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fec4e08c0be897de4956543892d747d
http://europepmc.org/articles/PMC8630774
http://europepmc.org/articles/PMC8630774
Autor:
Katie L. Davies, Emily J. Camm, Danielle J. Smith, Jack Miles, Alison J. Forhead, Andrew J. Murray, Abigail L. Fowden
Publikováno v:
Journal of developmental origins of health and disease.
Prenatal glucocorticoid overexposure causes adult metabolic dysfunction in several species but its effects on adult mitochondrial function remain largely unknown. Using respirometry, this study examined mitochondrial substrate metabolism of fetal and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4452c0a4d92737169a9a8b4443dc1b
https://pubmed.ncbi.nlm.nih.gov/35822505
https://pubmed.ncbi.nlm.nih.gov/35822505
Autor:
F. B. Peter Wooding, Dominique Blache, Abigail L. Fowden, Alison J. Forhead, Emily J. Camm, Isabella Inzani, Katie L. Davies, India R. Lloyd, Miles J. De Blasio
Publikováno v:
Thyroid. 31:861-869
Background: The fetal hypothalamic–pituitary–adrenal (HPA) axis plays a key role in the control of parturition and maturation of organ systems in preparation for birth. In hypothyroid fetuses, gest...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed9cc63e25e3aafeedbd26055f83c70b
https://doi.org/10.1089/thy.2020.0534
https://doi.org/10.1089/thy.2020.0534
Autor:
Abigail L. Fowden, Youguo Niu, Vanessa L Allen, N. Holdstock, Juanita K. Jellyman, Emilio A. Herrera, OA Valenzuela, Dino A. Giussani, Alison J. Forhead
Publikováno v:
Journal of Developmental Origins of Health and Disease. 12:309-318
Prenatal glucocorticoid overexposure has been shown to programme adult cardiovascular function in a range of species, but much less is known about the long-term effects of neonatal glucocorticoid overexposure. In horses, prenatal maturation of the hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e35f7891fd43b52365d21026ea91c21
https://doi.org/10.1017/s2040174420000446
https://doi.org/10.1017/s2040174420000446
Autor:
Miles J De Blasio, Maria Boije, Owen R Vaughan, Brett S Bernstein, Katie L Davies, Alice Plein, Sarah L Kempster, Gordon C S Smith, D Stephen Charnock-Jones, Dominique Blache, F B Peter Wooding, Dino A Giussani, Abigail L Fowden, Alison J Forhead
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0136115 (2015)
The effects of endogenous and synthetic glucocorticoids on fetal lung maturation are well-established, although the role of leptin in lung development before birth is unclear. This study examined mRNA and protein levels of the signalling long-form le
Externí odkaz:
https://doaj.org/article/150e20cb928e4e259bd56bf0a503b390
Publikováno v:
Equine Veterinary Journal. 52:165-173
In many species, the pattern of growth and physiological development in utero has an important role in determining not only neonatal viability but also adult phenotype and disease susceptibility. Changes in fetal development induced by a range of env
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::700ba347d99016558e5867ba4ad3c5cf
https://doi.org/10.1111/evj.13206
https://doi.org/10.1111/evj.13206
Autor:
Abigail L. Fowden, Alison J. Forhead
Publikováno v:
Domestic animal endocrinology. 78
Hormones have an important role in regulating fetal metabolism in relation to the prevailing nutritional conditions both in late gestation and during the prepartum period as the fetus prepares for birth. In particular, the pancreatic, thyroid and adr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91052c59fdc6a9431164dd51363390c1
https://pubmed.ncbi.nlm.nih.gov/34525421
https://pubmed.ncbi.nlm.nih.gov/34525421