Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Alison I. Bernstein"'
Autor:
Joseph R. Patterson, Joseph Kochmanski, Anna C. Stoll, Michael Kubik, Christopher J. Kemp, Megan F. Duffy, Kajene Thompson, Jacob W. Howe, Allyson Cole-Strauss, Nathan C. Kuhn, Kathryn M. Miller, Seth Nelson, Christopher U. Onyekpe, John S. Beck, Scott E. Counts, Alison I. Bernstein, Kathy Steece-Collier, Kelvin C. Luk, Caryl E. Sortwell
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-17 (2024)
Abstract Examination of early phases of synucleinopathy when inclusions are present, but long before neurodegeneration occurs, is critical to both understanding disease progression and the development of disease modifying therapies. The rat alpha-syn
Externí odkaz:
https://doaj.org/article/8bde4016617e4debb09532f2fc4a2cc0
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-13 (2022)
Abstract Evidence for epigenetic regulation playing a role in Parkinson’s disease (PD) is growing, particularly for DNA methylation. Approximately 90% of PD cases are due to a complex interaction between age, genes, and environmental factors, and e
Externí odkaz:
https://doaj.org/article/4cdfcdf39e54442ab2a0599f220e9af5
Autor:
Aysegul O. Gezer, Joseph Kochmanski, Sarah E. VanOeveren, Allyson Cole-Strauss, Christopher J. Kemp, Joseph R. Patterson, Kathryn M. Miller, Nathan C. Kuhn, Danielle E. Herman, Alyssa McIntire, Jack W. Lipton, Kelvin C. Luk, Sheila M. Fleming, Caryl E. Sortwell, Alison I. Bernstein
Publikováno v:
Neurobiology of Disease, Vol 141, Iss , Pp 104947- (2020)
Human and animal studies have shown that exposure to the organochlorine pesticide dieldrin is associated with increased risk of Parkinson's disease (PD). Previous work showed that developmental dieldrin exposure increased neuronal susceptibility to M
Externí odkaz:
https://doaj.org/article/212f253653d444c5bfd9ea221a1eac9e
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Epigenetic marks operate at multiple chromosomal levels to regulate gene expression, from direct covalent modification of DNA to three-dimensional chromosomal structure. Research has shown that 5-methylcytosine (5-mC) and its oxidized form, 5-hydroxy
Externí odkaz:
https://doaj.org/article/ea340d7f8e5e46ba871a6494931c28bd
Evidence for epigenetic regulation playing a role in Parkinson’s disease (PD) is growing, particularly for DNA modifications. Approximately 90% of PD cases are due to a complex interaction between age, genes, and environmental factors, and epigenet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf2852a46d9ebdb895c3d9adebab97a4
https://doi.org/10.1101/2021.09.08.459434
https://doi.org/10.1101/2021.09.08.459434
Publikováno v:
NPJ Parkinson's disease. 8(1)
Evidence for epigenetic regulation playing a role in Parkinson's disease (PD) is growing, particularly for DNA methylation. Approximately 90% of PD cases are due to a complex interaction between age, genes, and environmental factors, and epigenetic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4a4f30292c02b7958c19ba3aad34f3bd
https://pubmed.ncbi.nlm.nih.gov/36151217
https://pubmed.ncbi.nlm.nih.gov/36151217
Publikováno v:
Toxicol Sci
Human and animal studies have shown that exposure to the organochlorine pesticide dieldrin is associated with increased risk of Parkinson’s disease (PD). Despite previous work showing a link between developmental dieldrin exposure and increased neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e49b0a7d6d675b67095c994254e8bc1
https://doi.org/10.1093/toxsci/kfz069
https://doi.org/10.1093/toxsci/kfz069
Autor:
Alison I. Bernstein, Joseph Kochmanski
Publikováno v:
Curr Environ Health Rep
PURPOSE OF REVIEW: The aims of this review are to evaluate the methods used to measure 5-hydroxymethylcytosine (5-hmC), and then summarize the available data investigating the impact of environmental factors on 5-hydroxymethylcytosine (5-hmC) in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca51b4ed8c2d9dc83508ae3f2e73ee14
https://europepmc.org/articles/PMC7809708/
https://europepmc.org/articles/PMC7809708/
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Frontiers in Genetics
Frontiers in Genetics
Epigenetic marks operate at multiple chromosomal levels to regulate gene expression, from direct covalent modification of DNA to three-dimensional chromosomal structure. Research has shown that 5-methylcytosine (5-mC) and its oxidized form, 5-hydroxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e9c2002a909258cc827542af9b5c7d
https://www.frontiersin.org/article/10.3389/fgene.2019.00801/full
https://www.frontiersin.org/article/10.3389/fgene.2019.00801/full
Epigenetic marks operate at multiple chromosomal levels to regulate gene expression, from direct covalent modification of DNA to 3D chromosomal structure. Research has shown that 5-methylcytosine (5-mC) and its oxidized form, 5-hydroxymethylcytosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed07f85c0d8eb6d2627b1c1b5cfc4639
https://doi.org/10.1101/630772
https://doi.org/10.1101/630772