Zobrazeno 1 - 10 of 103 pro vyhledávání: '"Alison H, Thomson"'
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Akademický článek
Genetic Algorithms as a Tool for Dosing Guideline Optimization: Application to Intermittent Infusion Dosing for Vancomycin in Adults
Autor: Pieter J. Colin, Douglas J. Eleveld, Alison H. Thomson
Publikováno v: CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 5, Pp 294-302 (2020)
This paper demonstrates the use of a genetic algorithm (GA) for the optimization of a dosing guideline. GAs are well‐suited to derive combinations of doses and dosing intervals that go into a dosing guideline when the number of possible combination
Externí odkaz: https://doaj.org/article/b2b3e0abe4d74950a0c94b56efa9b032
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2
Do Vancomycin Pharmacokinetics Differ Between Obese and Non-obese Patients? Comparison of a General-purpose and Four Obesity-specific Pharmacokinetic Models
Autor: Alison H. Thomson, Pieter Colin, Andrew Hart, Douglas J. Eleveld
Publikováno v: Therapeutic Drug Monitoring
Therapeutic Drug Monitoring, 43(1), 126-130. LIPPINCOTT WILLIAMS & WILKINS
Objectives: Over the past decade, numerous obesity-specific pharmacokinetic (PK) models and dosage regimens have been developed. However, it is unclear whether vancomycin PKs differ between obese and other patients after accounting for weight, age, a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0684d72d0aff39e1358ed0e21bac8f
https://doi.org/10.1097/ftd.0000000000000832
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4
Vancomycin Pharmacokinetics Throughout Life: Results from a Pooled Population Analysis and Evaluation of Current Dosing Recommendations
Autor: Nicolas Simon, Pieter Colin, Dolores Santos-Buelga, Karel Allegaert, Michael J. Dolton, Michel Struys, Alison H. Thomson, Daniel J. Touw, Jason A. Roberts, Fabio Silvio Taccone, Ana Martín-Suárez, Matthijs de Hoog, Emilia Barcia, Masato Yamamoto, Lo Yl, Douglas J. Eleveld, Eyob Adane
Publikováno v: Clinical Pharmacokinetics, 58(6), 767-780. Adis
Clinical Pharmacokinetics, 58(6), 767-780. Springer International Publishing AG
Clinical Pharmacokinetics
Clinical Pharmacokinetics, Springer Verlag, 2019, 58 (6), pp.767-780. ⟨10.1007/s40262-018-0727-5⟩
Clinical pharmacokinetics, 58 (6
CLINICAL PHARMACOKINETICS
Background and Objectives: Uncertainty exists regarding the optimal dosing regimen for vancomycin in different patient populations, leading to a plethora of subgroup-specific pharmacokinetic models and derived dosing regimens. We aimed to investigate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba270c934ce37363a6f6e9c7e35d91e
https://doi.org/10.1007/s40262-018-0727-5
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5
Drug clearance in neonates : a combination of population pharmacokinetic modelling and machine learning approaches to improve individual prediction
Autor: Yue-E Wu, Alison H. Thomson, Yi Zheng, José Esteban Peris, Lo Yl, Bernd Meibohm, Edmund V. Capparelli, Wei Zhao, John N. van den Anker, Irja Lutsar, Hai-Yan Shi, Hai-Yan Xu, Xiao Li, Stéphanie Leroux, Karel Allegaert, Evelyne Jacqz-Aigrain, Bo Hao Tang, Yue Zhou, Xin Huang, Xiaoling Wang, Bao-Ping Xu, Bu-Fan Yao, Jacobus Burggraaf, Nicolas Simon, A.-Dong Shen, Chen Kou, Guo-Xiang Hao, Efthymios Manolis, Tian-You Wang, Remedios Marques, Valérie Biran, Jumpei Saito, Zheng Guan, Wen-Qi Wang
Publikováno v: Clinical Pharmacokinetics
Clinical Pharmacokinetics, 2021, 60, pp.1435-1448. ⟨10.1007/s40262-021-01033-x⟩
CLINICAL PHARMACOKINETICS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
International audience; Background Population pharmacokinetic evaluations have been widely used in neonatal pharmacokinetic studies, while machine learning has become a popular approach to solving complex problems in the current era of big data. Obje
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d59db76eafa7dc3be480fad546acaf27
https://strathprints.strath.ac.uk/77050/1/Tang_etal_CP_2021_Drug_clearance_in_neonates_a_combination_of_population_pharmacokinetic_modelling.pdf
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6
Population pharmacokinetic evaluation and optimization of amikacin dosage regimens for the management of mycobacterial infections
Autor: Alison H. Thomson, Hinke Siebinga, Fiona Robb
Background There is limited information on amikacin pharmacokinetics (PK) and dose requirements in patients with mycobacterial infections. Objectives To conduct a population PK analysis of amikacin data from patients with mycobacterial infections and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d6e7cdef72db0a3f7f4f4a881829e5
https://strathprints.strath.ac.uk/72493/1/Siebinga_etal_JAC_2020_Population_pharmacokinetic_evaluation_and_optimisation_of_amikacin_dosage.pdf
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7
Development and evaluation of a national gentamicin and vancomycin quality improvement programme
Autor: R Andrew Seaton, Marion Bennie, Jacqueline Sneddon, Alison Cockburn, Yvonne Semple, Alison H. Thomson
Background Scottish Antimicrobial Prescribing Group (SAPG) recommendations to reduce broad-spectrum antimicrobial use led to an increase in gentamicin and vancomycin prescribing. In 2009, SAPG introduced national guidance to standardize dosage regime
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751c95dbc9d2b191adb22f3a4981966e
https://strathprints.strath.ac.uk/71913/1/Semple_etal_JAC_2020_a_national_gentamicin_and_vancomycin_quality_improvement_programme.pdf
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8
Genetic algorithms as a tool for dosing guideline optimisation : application to intermittent infusion dosing for vancomycin in adults
Autor: Douglas J. Eleveld, Alison H. Thomson, Pieter Colin
Publikováno v: CPT: Pharmacometrics & Systems Pharmacology, 9(5), 294-302. Wiley
CPT: Pharmacometrics & Systems Pharmacology, Vol 9, Iss 5, Pp 294-302 (2020)
CPT: Pharmacometrics & Systems Pharmacology
This paper demonstrates the use of a genetic algorithm (GA) for the optimization of a dosing guideline. GAs are well-suited to derive combinations of doses and dosing intervals that go into a dosing guideline when the number of possible combinations
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06774b6cc66b4a7ac0d015ab7e4de0a2
https://strathprints.strath.ac.uk/72452/1/Colin_etal_CPT_PSP_2020_Genetic_algorithms_as_a_tool_for_dosing_guideline_optimisation.pdf
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9
Population pharmacokinetic meta-analysis of individual data to design the first randomized efficacy trial of vancomycin in neonates and young infants
Autor: Evelyne Jacqz-Aigrain, Johannes N. van den Anker, Alison H. Thomson, Stéphanie Leroux, Hidefumi Nakamura, Karel Allegaert, Remedios Marques, Edmund V. Capparelli, Irja Lutsar, Bernd Meibohm, Nicolas Simon, Jumpei Saito, Valérie Biran, Mike Sharland, José Esteban Peris, Wei Zhao, Lo Yl
Publikováno v: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy, Oxford University Press (OUP), 2019, 74 (8), pp.2128-2138. ⟨10.1093/jac/dkz158⟩
Journal of Antimicrobial Chemotherapy, 2019, 74 (8), pp.2128-2138. ⟨10.1093/jac/dkz158⟩
Journal of Antimicrobial Chemotherapy, 74(8), 2128-2138. Oxford University Press
Objectives In the absence of consensus, the present meta-analysis was performed to determine an optimal dosing regimen of vancomycin for neonates. Methods A ‘meta-model’ with 4894 concentrations from 1631 neonates was built using NONMEM, and Mont
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d45b678c5b8cf7f3589a33f7c9f75f
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10
Pharmacokinetic/pharmacodynamic analysis of weight- and height-scaled tobramycin dosage regimens for patients with cystic fibrosis
Autor: Daan J Touw, Sarah S. Alghanem, Alison H. Thomson
Publikováno v: Journal of Antimicrobial Chemotherapy, 74(8), 2311-2317. Oxford University Press
Objectives To determine the outcomes of weight- and height-based tobramycin dosing regimens for patients with cystic fibrosis (CF). Methods A simulated dataset of 5000 patients based on 331 patients with CF was created using NONMEM. Pharmacokinetic (
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90975a95eccc711ef948ad327420dfbd
https://pubmed.ncbi.nlm.nih.gov/31322695
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