Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Alison H, Holmes"'
Autor:
Richard C. Wilson, Alaa Riezk, Paul Arkell, Damien Ming, Ryan Armiger, Victoria Latham, Mark J. Gilchrist, Anne-Grete Märtson, William W. Hope, Alison H. Holmes, Timothy M. Rawson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract In the face of increasing antimicrobial tolerance and resistance there is a global obligation to optimise oral antimicrobial dosing strategies including narrow spectrum penicillins, such as penicillin-V. We conducted a randomised, crossover
Externí odkaz:
https://doaj.org/article/97703b0946e84335a208e8fd496377c1
Autor:
Stefan Karolcik, Vasileos Manginas, Ho Quang Chanh, John Daniels, Nguyen Thi Giang, Vu Ngo Thanh Huyen, Minh Tu Van Hoang, Khanh Phan Nguyen Quoc, Bernard Hernandez, Damien K. Ming, Hao Nguyen Van, Tu Qui Phan, Huynh Trung Trieu, Tai Luong Thi Hue, Alison H. Holmes, Louise Thwaites, Tho Phan Vinh, Sophie Yacoub, Pantelis Georgiou
Publikováno v:
EBioMedicine, Vol 104, Iss , Pp 105164- (2024)
Summary: Background: Dengue epidemics impose considerable strain on healthcare resources. Real-time continuous and non-invasive monitoring of patients admitted to the hospital could lead to improved care and outcomes. We evaluated the performance of
Externí odkaz:
https://doaj.org/article/cb4b3c9ceff44b998ac19afd183c2091
Autor:
Esmita Charani, PhD, Marc Mendelson, ProfPhD, Scott J C Pallett, MRCP, Raheelah Ahmad, PhD, Mirfin Mpundu, PhD, Oluchi Mbamalu, PhD, Candice Bonaconsa, MSc, Vrinda Nampoothiri, DPharm, Sanjeev Singh, PhD, Nathan Peiffer-Smadja, PhD, Vanesa Anton-Vazquez, MD, Luke S P Moore, PhD, Jeroen Schouten, PhD, Tomislav Kostyanev, PhD, Vera Vlahović-Palčevski, MD, Diamantis Kofteridis, PhD, Juliana Silva Corrêa, PhD, Alison H Holmes, ProfMD
Publikováno v:
The Lancet Global Health, Vol 11, Iss 3, Pp e466-e474 (2023)
Summary: At the 2015 World Health Assembly, UN member states adopted a resolution that committed to the development of national action plans (NAPs) for antimicrobial resistance (AMR). The political determination to commit to NAPs and the availability
Externí odkaz:
https://doaj.org/article/3518c43f773b4adeb0976b101b6d999f
Autor:
Bernard Hernandez, Oliver Stiff, Damien K. Ming, Chanh Ho Quang, Vuong Nguyen Lam, Tuan Nguyen Minh, Chau Nguyen Van Vinh, Nguyet Nguyen Minh, Huy Nguyen Quang, Lam Phung Khanh, Tam Dong Thi Hoai, Trung Dinh The, Trieu Huynh Trung, Bridget Wills, Cameron P. Simmons, Alison H. Holmes, Sophie Yacoub, Pantelis Georgiou, on behalf of the Vietnam ICU Translational Applications Laboratory (VITAL) investigators
Publikováno v:
Frontiers in Digital Health, Vol 5 (2023)
BackgroundIncreased data availability has prompted the creation of clinical decision support systems. These systems utilise clinical information to enhance health care provision, both to predict the likelihood of specific clinical outcomes or evaluat
Externí odkaz:
https://doaj.org/article/1fcfc49e867e490bb994ce99580dc679
Autor:
Damien K. Ming, Ashleigh C. Myall, Bernarnd Hernandez, Andrea Y. Weiße, Robert L. Peach, Mauricio Barahona, Timothy M. Rawson, Alison H. Holmes
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-7 (2021)
Abstract Background To characterise the longitudinal dynamics of C-reactive protein (CRP) and Procalcitonin (PCT) in a cohort of hospitalised patients with COVID-19 and support antimicrobial decision-making. Methods Longitudinal CRP and PCT concentra
Externí odkaz:
https://doaj.org/article/8cc97ea33545413e98a599626bbe4f0d
Autor:
William J. Bolton, Timothy M. Rawson, Bernard Hernandez, Richard Wilson, David Antcliffe, Pantelis Georgiou, Alison H. Holmes
Publikováno v:
Frontiers in Digital Health, Vol 4 (2022)
The decision on when it is appropriate to stop antimicrobial treatment in an individual patient is complex and under-researched. Ceasing too early can drive treatment failure, while excessive treatment risks adverse events. Under- and over-treatment
Externí odkaz:
https://doaj.org/article/df30422d9c86484d95f09d61081033b8
Autor:
Damien K. Ming, Nguyen M. Tuan, Bernard Hernandez, Sorawat Sangkaew, Nguyen L. Vuong, Ho Q. Chanh, Nguyen V. V. Chau, Cameron P. Simmons, Bridget Wills, Pantelis Georgiou, Alison H. Holmes, Sophie Yacoub
Publikováno v:
Frontiers in Digital Health, Vol 4 (2022)
BackgroundSymptomatic dengue infection can result in a life-threatening shock syndrome and timely diagnosis is essential. Point-of-care tests for non-structural protein 1 and IgM are used widely but performance can be limited. We developed a supervis
Externí odkaz:
https://doaj.org/article/4b39b4689ca4433abec43b392eb03340
Autor:
Sara E. Boyd, Anupama Vasudevan, Luke S.P. Moore, Christopher Brewer, Mark Gilchrist, Ceire Costelloe, Anthony C. Gordon, Alison H. Holmes
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 22, Iss , Pp 826-831 (2020)
Background: The Singapore GSDCS score was developed to enable clinicians predict the risk of nosocomial multidrug-resistant Gram-negative bacilli (RGNB) infection in critically ill patients. We aimed to validate this score in a UK setting. Method: A
Externí odkaz:
https://doaj.org/article/3edbb0cec2234082ac13bc2911a6bb61
Autor:
Damien K. Ming, Sorawat Sangkaew, Ho Q. Chanh, Phung T.H. Nhat, Sophie Yacoub, Pantelis Georgiou, Alison H. Holmes
Publikováno v:
International Journal of Infectious Diseases, Vol 96, Iss , Pp 648-654 (2020)
Optimal management of infectious diseases is guided by up-to-date information at the individual and public health levels. For infections of global importance, including emerging pandemics such as COVID-19 or prevalent endemic diseases such as dengue,
Externí odkaz:
https://doaj.org/article/7ad04db57ed043a8b0723fd0b92e0bcc
Autor:
Damien K Ming, Bernard Hernandez, Sorawat Sangkaew, Nguyen Lam Vuong, Phung Khanh Lam, Nguyen Minh Nguyet, Dong Thi Hoai Tam, Dinh The Trung, Nguyen Thi Hanh Tien, Nguyen Minh Tuan, Nguyen Van Vinh Chau, Cao Thi Tam, Ho Quang Chanh, Huynh Trung Trieu, Cameron P Simmons, Bridget Wills, Pantelis Georgiou, Alison H Holmes, Sophie Yacoub, Vietnam ICU Translational Applications Laboratory (VITAL) investigators
Publikováno v:
PLOS Digital Health, Vol 1, Iss 1, p e0000005 (2022)
BackgroundIdentifying patients at risk of dengue shock syndrome (DSS) is vital for effective healthcare delivery. This can be challenging in endemic settings because of high caseloads and limited resources. Machine learning models trained using clini
Externí odkaz:
https://doaj.org/article/baf8220fecff40a8888cec9897258431