Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alison Gaudion"'
Autor:
Matt Davies, Simon Cozens, Morris Muliaditan, Adeep Puri, Andrew Skingsley, Alison Gaudion, David Tenero, Alfonso Mendoza-Losana, John Tonkyn, Joaquin Rullas-Trincado, Alex Carlton, Stephanie Gresham, Geo Derimanov, David Barros-Aguirre
Publikováno v:
Antimicrobial Agents and Chemotherapy
This first-time-in-human (FTIH) study evaluated the safety, tolerability, pharmacokinetics, and food effect of single and repeat oral doses of GSK3036656, a leucyl-tRNA synthetase inhibitor. In part A, GSK3036656 single doses of 5 mg (fed and fasted)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bfbc11cd17d99730c0a1ebcfc8d9bc7
https://doi.org/10.1128/aac.00240-19
https://doi.org/10.1128/aac.00240-19
Autor:
Mark C. Enright, Jessica E. Bean, Patricia Perez Esteban, A.T.A. Jenkins, Diana R. Alves, Alison Gaudion, Amber Young, Tom Arnot
Publikováno v:
Biotechnology Progress. 30:932-944
Bacteriophage therapy is a promising new treatment that may help overcome the threat posed by antibiotic-resistant pathogenic bacteria, which are increasingly identified in hospitalized patients. The development of biocompatible and sustainable vehic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::434fc52b1fb90752e1d840d27817420a
https://doi.org/10.1002/btpr.1898
https://doi.org/10.1002/btpr.1898
Publikováno v:
Tuberculosis (Edinburgh, Scotland)
Gaudion, A, Dawson, L, Davis, E & Smollett, K 2013, ' Characterisation of the Mycobacterium tuberculosis alternative sigma factor SigG : Its operon and regulon ', Tuberculosis, vol. 93, no. 5, pp. 482-491 . https://doi.org/10.1016/j.tube.2013.05.005
Gaudion, A, Dawson, L, Davis, E & Smollett, K 2013, ' Characterisation of the Mycobacterium tuberculosis alternative sigma factor SigG : Its operon and regulon ', Tuberculosis, vol. 93, no. 5, pp. 482-491 . https://doi.org/10.1016/j.tube.2013.05.005
Summary A major step in the pathogenesis of Mycobacterium tuberculosis is the ability to survive inside macrophages, where it is exposed to a number of DNA damaging agents. The alternative sigma factor SigG has been shown to be upregulated by DNA dam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ff0745efa97b1050db9fff6584e271d
http://europepmc.org/articles/PMC3776920
http://europepmc.org/articles/PMC3776920
Autor:
Patricia Perez, Esteban, Diana R, Alves, Mark C, Enright, Jessica E, Bean, Alison, Gaudion, A T A, Jenkins, Amber E R, Young, Tom C, Arnot
Publikováno v:
Biotechnology progress. 30(4)
Bacteriophage therapy is a promising new treatment that may help overcome the threat posed by antibiotic-resistant pathogenic bacteria, which are increasingly identified in hospitalized patients. The development of biocompatible and sustainable vehic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5276545ba50cb529ec41375b3d894372
https://pubmed.ncbi.nlm.nih.gov/24616404
https://pubmed.ncbi.nlm.nih.gov/24616404