Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Alison Gartland"'
Autor:
Jennifer C. Coleman, Luke Tattersall, Val Yianni, Laura Knight, Hongqiang Yu, Sadie R. Hallett, Philip Johnson, Ana J. Caetano, Charlie Cosstick, Anne J. Ridley, Alison Gartland, Maria R. Conte, Agamemnon E. Grigoriadis
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109288- (2024)
Summary: RNA-binding proteins (RBPs) are emerging as important regulators of cancer pathogenesis. We reveal that the RBPs LARP4A and LARP4B are differentially overexpressed in osteosarcoma and osteosarcoma lung metastases, as well as in prostate canc
Externí odkaz:
https://doaj.org/article/e05b9197d6e846339a41025635e63f0c
Autor:
Haiping Song, Hector Manuel Arredondo Carrera, Alexandria Sprules, Ying Ji, Tongsong Zhang, Jiepei He, Eleanor Lawrence, Alison Gartland, Jian Luo, Ning Wang
Publikováno v:
Cancer Communications, Vol 43, Iss 3, Pp 400-404 (2023)
Externí odkaz:
https://doaj.org/article/5a2f8258829145a8a2388d76220676fb
Autor:
Darrell Green, Archana Singh, Victoria L. Tippett, Luke Tattersall, Karan M. Shah, Chileleko Siachisumo, Nicole J. Ward, Paul Thomas, Simon Carter, Lee Jeys, Vaiyapuri Sumathi, Iain McNamara, David J. Elliott, Alison Gartland, Tamas Dalmay, William D. Fraser
Publikováno v:
Journal of Bone Oncology, Vol 39, Iss , Pp 100474- (2023)
Primary bone cancer (PBC) comprises several subtypes each underpinned by distinctive genetic drivers. This driver diversity produces novel morphological features and clinical behaviour that serendipitously makes PBC an excellent metastasis model. Her
Externí odkaz:
https://doaj.org/article/4879f410a6f04bfca0f55c50fb4bf523
Autor:
Yunyun Jin, Qianqian Liu, Peng Chen, Siyuan Zhao, Wenhao Jiang, Fanhua Wang, Peng Li, Yuanjin Zhang, Weiqiang Lu, Tao P. Zhong, Xinran Ma, Xin Wang, Alison Gartland, Ning Wang, Karan Mehul Shah, Hankun Zhang, Xu Cao, Lei Yang, Mingyao Liu, Jian Luo
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-22 (2022)
Abstract Articular cartilage repair and regeneration is an unmet clinical need because of the poor self-regeneration capacity of the tissue. In this study, we found that the expression of prostaglandin E receptor 4 (PTGER4 or EP4) was largely increas
Externí odkaz:
https://doaj.org/article/161767aabd3c428e989a0cb6164e63b4
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/4ce71667c7a44c498e451028af9218af
Autor:
Ankita Agrawal, Maria Ellegaard, Kristian Agmund Haanes, Ning Wang, Alison Gartland, Ming Ding, Helle Praetorius, Niklas Rye Jørgensen
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Increased incidence of bone fractures in the elderly is associated with gradual sarcopenia. Similar deterioration of bone quality is seen with prolonged bed rest, spinal cord injuries or in astronauts exposed to microgravity and, preceded by loss of
Externí odkaz:
https://doaj.org/article/181f1e03eb4d45739d93f12c0b4444f6
Autor:
Zhiying Yue, Xin Niu, Zengjin Yuan, Qin Qin, Wenhao Jiang, Liang He, Jingduo Gao, Yi Ding, Yanxi Liu, Ziwei Xu, Zhenxi Li, Zhengfeng Yang, Rong Li, Xiwen Xue, Yankun Gao, Fei Yue, Xiang H.-F. Zhang, Guohong Hu, Yi Wang, Yi Li, Geng Chen, Stefan Siwko, Alison Gartland, Ning Wang, Jianru Xiao, Mingyao Liu, Jian Luo
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 2 (2022)
Therapeutics targeting osteoclasts are commonly used treatments for bone metastasis; however, whether and how osteoclasts regulate premetastatic niche and bone tropism are largely unknown. In this study, we report that osteoclast precursors (OPs) can
Externí odkaz:
https://doaj.org/article/bc28f8256df64fe189ac58cf485bf56c
Autor:
Luke Tattersall, Karan M. Shah, Darren L. Lath, Archana Singh, Jennifer M. Down, Elena De Marchi, Alex Williamson, Francesco Di Virgilio, Dominique Heymann, Elena Adinolfi, William D. Fraser, Darrell Green, Michelle A. Lawson, Alison Gartland
Publikováno v:
Journal of Bone Oncology, Vol 31, Iss , Pp 100398- (2021)
Background: Osteosarcoma (OS) is the most common type of primary bone cancer affecting children and adolescents. OS has a high propensity to spread meaning the disease is often incurable and fatal. There have been no improvements in survival rates fo
Externí odkaz:
https://doaj.org/article/f6ea4743af554aa6aa8602c00e6fec57
Autor:
George A. E. Pickering, Favour Felix-Ilemhenbhio, Matthew J. Clark, Klaudia Kocsy, Jonathan Simpson, Ilaria Bellantuono, Alison Gartland, Jeremy Mark Wilkinson, Konstantinos Hatzikotoulas, Endre Kiss-Toth
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9203 (2022)
The formation of pathological bone deposits within soft tissues, termed heterotopic ossification (HO), is common after trauma. However, the severity of HO formation varies substantially between individuals, from relatively isolated small bone islands
Externí odkaz:
https://doaj.org/article/f144f185821b4d7ebe3d1a6fff61447b
Autor:
Luke Tattersall, Dan C Gagui, Victoria L Tippett, Norain B Ab Latif, Karan M Shah, Alison Gartland
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 27, Iss 4, p 122 (2022)
Primary bone cancers are rare malignant diseases with significant morbidity and mortality. The treatment regimen relies on a combination of surgery (often involving amputation), chemotherapy and radiotherapy with outcomes dependent on localization of
Externí odkaz:
https://doaj.org/article/12f853e2f7b14c41889efe1de984682e