Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Alison E Meyer"'
Autor:
Paula E Miller, Aksharananda Rambachan, Roderick J Hubbard, Jiabai Li, Alison E Meyer, Peter Stephens, Anthony W Mounts, Melissa A Rolfes, Charles R Penn
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43491 (2012)
BACKGROUND: The influenza A (H1N1) pandemic swept across the globe from April 2009 to August 2010 affecting millions. Many WHO Member States relied on antiviral drugs, specifically neuraminidase inhibitors (NAIs) oseltamivir and zanamivir, to treat i
Externí odkaz:
https://doaj.org/article/cd33dc3d4fe24f37b4cc444a55a7525f
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 3, Pp 337-347 (2021)
Acute myeloid leukemia (AML) affects tens of thousands of patients a year, yet survival rates are as low as 25% in certain populations. This poor survival rate is partially due to the vast genetic diversity of the disease. Rarely do 2 patients with A
Externí odkaz:
https://doaj.org/article/2965a902d6aa4590ab37676161280f27
Autor:
Alison E. Meyer, Sridhar Rao, Aaron D. Viny, Katelyn E. Heimbruch, Adam J. Wargolet, Kirthi Pulakanti, Emily Kristine Phillips, Jessica J. Loppnow, Ross L. Levine, Joseph B. Fisher, John Anto Pulikkan, Nan Zhu, Michael Reimer, Cary Stelloh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Acute myeloid leukemia (AML) is a high-risk malignancy characterized by a diverse spectrum of somatic genetic alterations. The mechanisms by which these mutations contribute to leukemia development and how this informs the use of targeted therapies i
Publikováno v:
Cancers. 15:1443
Myeloid sarcomas (MS), commonly referred to as chloromas, are extramedullary tumors of acute myeloid leukemia (AML) with varying incidence and influence on outcomes. Pediatric MS has both a higher incidence and unique clinical presentation, cytogenet
Loss of Fbxw7 triggers mammary tumorigenesis associated with E2F/c-Myc activation and Trp53 mutation
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 11, Pp 644-658 (2020)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
Fbw7 is a tumor suppressor that regulates the degradation of oncogenic substrates such as c-Jun, c-Myc, Notch1 intracellular domain (ICD), and cyclin E by functioning as the substrate recognition protein in the Skp1-Cullin-F-box (SCF) ubiquitin ligas
Publikováno v:
Blood. 140:5884-5884
Autor:
Alison E. Meyer, Cary Stelloh, Kirthi Pulakanti, Robert Burns, Joseph B. Fisher, Katelyn E. Heimbruch, Sergey Tarima, Quinlan Furumo, John Brennan, Yongwei Zheng, Aaron D. Viny, George S. Vassiliou, Sridhar Rao
Publikováno v:
Leukemia
Acute myeloid leukemia (AML) is driven by mutations that occur in numerous combinations. A better understanding of how mutations interact with one another to cause disease is critical to developing targeted therapies. Approximately 50% of patients th
Autor:
Katelyn E. Heimbruch, George S. Vassiliou, Joseph B. Fisher, Sridhar Rao, Kirthi Pulakanti, Sergey Tarima, Robert Burns, Alison E. Meyer, Cary Stelloh, Aaron D. Viny
Publikováno v:
Blood. 138:3288-3288
Acute myeloid leukemia (AML) is an aggressive malignancy of the blood and bone marrow resulting from the accumulation of multiple serially acquired mutations. The mutational complexity of the disease makes AML difficult to treat, contributing to a lo
Autor:
Michael Reimer, Steven Blinka, Sridhar Rao, Puja Agrawal, Kirthi Pulakanti, Cary Stelloh, Alison E. Meyer
Publikováno v:
The Journal of Biological Chemistry
Transcriptional enhancers have been defined by their ability to operate independent of distance and orientation in plasmid-based reporter assays of gene expression. At present, histone marks are used to identify and define enhancers but do not consid
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1853:1035-1045
J-proteins, obligate co-chaperones, provide specialization for Hsp70 function in a variety of cellular processes. Two of the 13 J-proteins of the yeast cytosol/nucleus, Zuo1 and Jjj1, are associated with 60S ribosomal subunits. Abundant Zuo1 facilita