Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Alison E Mahan"'
Autor:
Galit Alter, Karen G Dowell, Eric P Brown, Todd J Suscovich, Anastassia Mikhailova, Alison E Mahan, Bruce D Walker, Falk Nimmerjahn, Chris Bailey‐Kellogg, Margaret E Ackerman
Publikováno v:
Molecular Systems Biology, Vol 14, Iss 3, Pp 1-14 (2018)
Abstract Defining correlates of immunity by comprehensively interrogating the extensive biological diversity in naturally or experimentally protected subjects may provide insights critical for guiding the development of effective vaccines and antibod
Externí odkaz:
https://doaj.org/article/65c2addc89f34bf09e9d6417288b5ddb
Autor:
Alison E Mahan, Madeleine F Jennewein, Todd Suscovich, Kendall Dionne, Jacquelynne Tedesco, Amy W Chung, Hendrik Streeck, Maria Pau, Hanneke Schuitemaker, Don Francis, Patricia Fast, Dagna Laufer, Bruce D Walker, Lindsey Baden, Dan H Barouch, Galit Alter
Publikováno v:
PLoS Pathogens, Vol 12, Iss 6, p e1005694 (2016)
[This corrects the article DOI: 10.1371/journal.ppat.1005456.].
Externí odkaz:
https://doaj.org/article/38a0e1329c4b48319726437ed40f4767
Autor:
Alison E Mahan, Madeleine F Jennewein, Todd Suscovich, Kendall Dionne, Jacquelynne Tedesco, Amy W Chung, Hendrik Streeck, Maria Pau, Hanneke Schuitemaker, Don Francis, Patricia Fast, Dagna Laufer, Bruce D Walker, Lindsey Baden, Dan H Barouch, Galit Alter
Publikováno v:
PLoS Pathogens, Vol 12, Iss 3, p e1005456 (2016)
Antibody effector functions, such as antibody-dependent cellular cytotoxicity, complement deposition, and antibody-dependent phagocytosis, play a critical role in immunity against multiple pathogens, particularly in the absence of neutralizing activi
Externí odkaz:
https://doaj.org/article/f6be0b9a5a874f1cbc6558a62cdcd27c
Autor:
Hendrik Streeck, Jeffrey R. Schneider, Kelly M. Fahrbach, Alison E. Mahan, Bronwyn M. Gunn, Thomas J. Hope, Shiv Pillai, Bruce D. Walker, Igal Szleifer, Anna Licht, Archer D. Smith, Neil L. Kelleher, Patrick F. Kiser, David C. Malaspina, Meegan R. Anderson, Ivan Zvonar, Anais Chapel, Marcus M. Karim, Todd J. Suscovich, Arthur Y. Kim, Galit Alter, Maryam Shansab, Marcus Altfeld, Jacquelynn Tedesco, Georg M. Lauer, Arangassery Rosemary Bastian
Publikováno v:
Mucosal immunology
Transmission of HIV across mucosal barriers accounts for the majority of HIV infections worldwide. Thus, efforts aimed at enhancing protective immunity at these sites are a top priority, including increasing virus-specific antibodies (Abs) and antivi
Autor:
Galit Alter, Diana Chen, Ryan P. Staupe, John R. Teijaro, E. John Wherry, Pamela M. Odorizzi, Alison E. Mahan, Burton E. Barnett, Steven L. Reiner, Olesya Palko, Bronwyn M. Gunn, Georg M. Lauer, Vesselin T. Tomov, Michael A. Paley
Publikováno v:
The Journal of Immunology. 197:1017-1022
The role of Ab and B cells in preventing infection is established. In contrast, the role of B cell responses in containing chronic infections remains poorly understood. IgG2a (IgG1 in humans) can prevent acute infections, and T-bet promotes IgG2a iso
Autor:
Mangala Rao, Ying N. Chan, Galit Alter, Nana Yaw Osei-Owusu, Genoveffa Franchini, Alison E. Mahan, Erica Normandin, Jennifer I. Lai, Margaret E. Ackerman, Eric P. Brown, Monica Vaccari
Publikováno v:
Journal of Immunological Methods. 425:27-36
Glycosylation of the Fc domain is an important driver of antibody effector function. While assessment of antibody glycoform compositions observed across total plasma IgG has identified differences associated with a variety of clinical conditions, in
Autor:
Margaret E. Ackerman, Galit Alter, Andrew R. Crowley, James H. Kappel, Austin W. Boesch, Thach H. Chu, Alison E. Mahan, Nana Yaw Osei-Owusu
Publikováno v:
Biotechnology and bioengineering. 115(5)
As antibodies continue to gain predominance in drug discovery and development pipelines, efforts to control and optimize their activity in vivo have matured to incorporate sophisticated abilities to manipulate engagement of specific Fc binding partne
Autor:
Constance J. Martin, Sarah M. Fortune, Hendrik Streeck, Alison E. Mahan, Musie Ghebremichael, Tracy R. Rosebrock, Galit Alter, Elizabeth Tkachenko, Manu P. Kumar, Lenette L. Lu, Katherine J. Freedberg, Vivian Leung, Fikadu G. Tafesse, Todd J. Suscovich, Wen-Han Yu, Patricia S. Grace, Hannah Robinson, Matthew K. Schoen, Jacquelynne Tedesco, Monia Draghi, Cheryl L. Day, Magdalena Sips, Douglas A. Lauffenburger, Blanca I. Restrepo, Amy W. Chung
Publikováno v:
PMC
While a third of the world carries the burden of tuberculosis, disease control has been hindered by a lack of tools, including a rapid, point-of-care diagnostic and a protective vaccine. In many infectious diseases, antibodies (Abs) are powerful biom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47401246b9123a3a2c1569787a483fff
https://europepmc.org/articles/PMC5526202/
https://europepmc.org/articles/PMC5526202/
Autor:
Todd J. Suscovich, Lindsey R. Baden, Maria Pau, Dagna Laufer, Hanneke Schuitemaker, Bruce D. Walker, Hendrik Streeck, Patricia E. Fast, Dan H. Barouch, Donald P. Francis, Kendall Dionne, Alison E. Mahan, Amy W. Chung, Galit Alter, Madeleine F. Jennewein, Jacquelynne Tedesco
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 6, p e1005694 (2016)
PLoS Pathogens, Vol 12, Iss 6, p e1005694 (2016)
Antibody effector functions, such as antibody-dependent cellular cytotoxicity, complement deposition, and antibody-dependent phagocytosis, play a critical role in immunity against multiple pathogens, particularly in the absence of neutralizing activi
Publikováno v:
Scientific Reports
Nature Publishing Group
Nature Publishing Group
Isolation of low abundance proteins or rare cells from complex mixtures, such as blood, is required for many diagnostic, therapeutic and research applications. Current affinity-based protein or cell separation methods use binary ‘bind-elute’ sepa