Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Alison Drury"'
Autor:
Jill Hamilton, Alison Drury, Alison Hardy, Lucy Brady, Rachel Lopata, Sally Dickinson, Zoe Clark, Liz Marshall, Joe Eddison, Dale Webb
Publikováno v:
Rheumatology. 62
Background/Aims Services for axial spondyloarthritis (axial SpA) are informed in the UK by NICE Guideline 65 (2017) and Quality Standard 170 (2018), and internationally by the European Alliance of Associations for Rheumatology (EULAR) Recommendations
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
miR-139-5p overexpression significantly increased radiation sensitivity in 10 BC cell lines (A-I), and also sensitivity to ROS generator menadione (J).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1af9f98530e31300fe125ac252f05b19
https://doi.org/10.1158/0008-5472.22417851
https://doi.org/10.1158/0008-5472.22417851
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
miR-139-5p mimic transfection sensitized MCF7 cells to a fractionated radiation dose.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b063a366ab14c4b3f8b57327f6b6dc60
https://doi.org/10.1158/0008-5472.22417857.v1
https://doi.org/10.1158/0008-5472.22417857.v1
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
Comparative genomics of predicted miR-139-5p binding sites across 15 eutherian mammals (A). Correlation between endogenous miR-139-5p expression and predicted targets in 207 primary BC tumors (B).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1953aa9840e2b24f878461e4da86a437
https://doi.org/10.1158/0008-5472.22417854
https://doi.org/10.1158/0008-5472.22417854
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
Supplementary Tables 1-6 Supp. Table 1: Clinicopathological characteristics of breast cancer patients whose tumours were profiled by miRNA expression microarrays to identify miRNAs associated with local relapse following radiotherapy. Supp. Table 2:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f951d92c4452a370f5c128e23ffa4fa
https://doi.org/10.1158/0008-5472.22417845
https://doi.org/10.1158/0008-5472.22417845
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
Radiotherapy is essential to the treatment of most solid tumors and acquired or innate resistance to this therapeutic modality is a major clinical problem. Here we show that miR-139-5p is a potent modulator of radiotherapy response in breast cancer v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c26eaaad942be250caced776fa8fee5
https://doi.org/10.1158/0008-5472.c.6509961
https://doi.org/10.1158/0008-5472.c.6509961
Autor:
Timothy J. Molloy, Georgina E. Hollway, Harriet E. Gee, Francesca M. Buffa, Adrian L Harris, Sandra A. O’Toole, Joanne Toohey, Susan Carroll, Anaiis Zaratzian, Alice Boulghourjian, Charles E. de Bock, Angela Steinmann, Alison Drury, Peter H. Graham, Ewan Millar, Louise Doculara, Sheridan Daly, Danielle Froio, Marina Pajic
RT + miR-139-5p mimic-treated tumours had significantly decreased Ki-67-positive cells, and significantly increased phospho-H2AX- and caspase-3-positive cells compared to control mimic-treated tumours (A-C). phospho-H2AX immunostaining was confined t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12aa8628a42b861b37b85c2ec67b9b2a
https://doi.org/10.1158/0008-5472.22417848.v1
https://doi.org/10.1158/0008-5472.22417848.v1
Autor:
John Turchini, Danielle Froio, Paul Timpson, Marina Pajic, Stacey N. Walters, Amber L. Johns, Mark J. Cowley, Angela Steinmann, Thomas R. Cox, Shane T. Grey, Andrew Burgess, Claire Vennin, David K. Chang, Owen J. Sansom, Dalia Wohl, Timothy J. Molloy, Andrew V. Biankin, Angela Chou, Adnan Nagrial, Lorraine A. Chantrill, Rhys Stark, Mark Pinese, Stephen Clarke, Jaswinder S. Samra, Alison Drury, Ashleigh Parkin, Venessa T. Chin, Kendelle J. Murphy, Sean M. Grimmond, Nicola Waddell, Jennifer P. Morton, Anthony J. Gill
Publikováno v:
Gut
ObjectiveExtensive molecular heterogeneity of pancreatic ductal adenocarcinoma (PDA), few effective therapies and high mortality make this disease a prime model for advancing development of tailored therapies. The p16-cyclin D-cyclin-dependent kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f16f383a8580141705662de52823c31
https://eprints.gla.ac.uk/151422/1/151422.pdf
https://eprints.gla.ac.uk/151422/1/151422.pdf
Autor:
Peter Graham, Ewan K.A. Millar, Louise Doculara, Georgina E Hollway, Charles E. de Bock, Joanne Toohey, Anaiis Zaratzian, Harriet E. Gee, Danielle Froio, Alice Boulghourjian, Susan Carroll, Alison Drury, Marina Pajic, Sheridan Daly, Timothy J. Molloy, Francesca M. Buffa, Adrian L. Harris, Sandra A O'Toole, Angela Steinmann
Publikováno v:
Cancer research. 78(2)
Radiotherapy is essential to the treatment of most solid tumors and acquired or innate resistance to this therapeutic modality is a major clinical problem. Here we show that miR-139-5p is a potent modulator of radiotherapy response in breast cancer v
Autor:
Renee Whan, Danielle Froio, Andrew Burgess, Rohit Jain, David Gallego-Ortega, Paul Timpson, Maija R.J. Kohonen-Corish, Pauline Mélénec, Amr H. Allam, Shane T. Grey, Sean C. Warren, Thomas R. Cox, Anthony J. Gill, Amber L. Johns, Anaiis Zaratzian, Jaswinder S. Samra, Celine Heu, Morghan C. Lucas, Tri Giang Phan, Angela Steinmann, Lorraine A. Chantrill, Nathanial L. E. Harris, Alice Boulghourjian, Yingxiao Wang, Adnan Nagrial, Alison Drury, Arne A. S. Adam, Claire Vennin, Owen J. Sansom, Christopher J. Ormandy, Nicola Currey, Marina Pajic, Angela Chou, Michael S. Samuel, Stacey N. Walters, Wolfgang Weninger, T.R. Jeffry Evans, Venessa T. Chin, Kurt I. Anderson, Richard P. Harvey, James R.W. Conway, Andrew V. Biankin, Jennifer P. Morton, Astrid Magenau, Rachael A. McCloy, Ewan J. McGhee, Max Nobis, David Herrmann, Marc Giry-Laterriere, Gonzalo del Monte-Nieto, Mark Pinese
Publikováno v:
Science translational medicine. 9(384)
The emerging standard of care for patients with inoperable pancreatic cancer is a combination of cytotoxic drugs gemcitabine and Abraxane, but patient response remains moderate. Pancreatic cancer development and metastasis occur in complex settings,