Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alison D. Short"'
Publikováno v:
Biochemical Journal. 351:683-686
In cells expressing different receptors linked to Ins(1,4,5)P(3) formation, maximal stimulation of any one of them often releases all the Ins(1,4,5)P(3)-sensitive Ca(2+) stores, suggesting that Ins(1,4, 5)P(3) is used similarly by many receptors. In
Autor:
Alison D. Short, Colin W. Taylor
Publikováno v:
Journal of Biological Chemistry. 275:1807-1813
In HEK 293 cells stably expressing type 1 parathyroid (PTH) receptors, PTH stimulated release of intracellular Ca(2+) stores in only 27% of cells, whereas 96% of cells responded to carbachol. However, in almost all cells PTH potentiated the response
Publikováno v:
Biochemical Journal. 342:199-206
In A7r5 cells with empty intracellular Ca(2+) stores in which the cytosolic free Ca(2+) concentration ([Ca(2+)](i)) had been increased by capacitative Ca(2+) entry, stimulation of receptors linked to phospholipase C (PLC), including those for Arg(8)-
Publikováno v:
Journal of Biological Chemistry. 270:26790-26793
Ca2+ pool depletion with Ca2+ pump blockers induces growth arrest of rapidly dividing DDT1MF-2 smooth muscle cells and causes cells to enter a stable, quiescent G0-like growth state (Short, A.D., Bian, J., Ghosh, T.K., Waldron, R.T., Rybak, S.L., and
Publikováno v:
Journal of Biological Chemistry. 270:11955-11961
Exposure of cells to the intracellular Ca2+ pump blocker, thapsigargin (TG), results in emptying of Ca2+ pools and termination of cell proliferation (Short, A. D., Bian, J., Ghosh, T. K., Waldron, R. T., Rybak, S. L., and Gill, D. L. (1993) Proc. Nat
Publikováno v:
Journal of Biological Chemistry. 269:11927-11933
Intracellular Ca2+ pump expression and Ca2+ pool function are shown to be closely associated with growth and proliferation of DDT1MF-2 hamster smooth muscle cells. The Ca2+ pump blocker thapsigargin induces sustained Ca2+ pool emptying and entry of c
Publikováno v:
Journal of Biological Chemistry. 268:25887-25893
The distribution and operation of Ca2+ pools within cells has been directly studied in situ by monitoring the Ca2+ inside Ca2+ dye-loaded organelles using high resolution imaging procedures. Using DDT1MF-2 smooth muscle cells, loaded with fura-2 unde
Autor:
Junhui Bian, Sheree L. Rybak, Donald L. Gill, Alison D. Short, Tarun K. Ghosh, Richard T. Waldron
Publikováno v:
Proceedings of the National Academy of Sciences. 90:4986-4990
A close correlation was observed between intracellular Ca2+ pool depletion and refilling and the onset of DNA synthesis and proliferation of DDT1MF-2 smooth muscle cells. The intracellular Ca2+ pump inhibitors 2,5-di-tert-butyl-hydroquinone (DBHQ) an
Publikováno v:
Journal of Biological Chemistry. 266:24690-24697
The intracellular Ca2+ pump inhibitor, thapsigargin, added to DDT1MF-2 smooth muscle cells in culture, irreversibly inhibited accumulation of Ca2+ within cells, permanently emptied the inositol 1,4,5-trisphosphate (InsP3)-sensitive Ca2+ pool, and sim
Autor:
Kanwar Virdee, C. Paul Plested, Henrik Skjodt, Barry L. Brown, R. Graham G. Russell, Alison D. Short, Pauline R.M. Dobson
Publikováno v:
Regulatory Peptides. 29:109-116
Despite advances in the knowledge of the intracellular signalling in response to extracellular messengers, the mechanism of action of interleukin-1 (IL-1) has remained an enigma. In the present study, we have employed human dermal fibroblasts (Detroi