Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Alison Colquhoun"'
Autor:
Vanessa B. Candido, Sany M. Perego, Alexandre Ceroni, Martin Metzger, Alison Colquhoun, Lisete C. Michelini
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Chronic hypertension is accompanied by either blood-brain barrier (BBB) leakage and autonomic dysfunction. There is no consensus on the mechanism determining increased BBB permeability within autonomic areas. While some reports suggeste
Externí odkaz:
https://doaj.org/article/83feaa3b87d14e28959124882dbc0d8c
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 779 (2023)
Glioblastomas (GBMs) are notoriously difficult to treat, and the development of multiple drug resistance (MDR) is common during the course of the disease. The polyunsaturated fatty acids (PUFAs) gamma-linolenic acid (GLA), eicosapentaenoic acid (EPA)
Externí odkaz:
https://doaj.org/article/2c9f82151a0e4853b36c795b9590253b
Autor:
Juan de los Santos-Jiménez, José A. Campos-Sandoval, Clara Márquez-Torres, Nieves Urbano-Polo, David Brøndegaard, Mercedes Martín-Rufián, Carolina Lobo, Ana Peñalver, María C. Gómez-García, Janet Martín-Campos, Carolina Cardona, Laura Castilla, Felipe da Costa Souza, Tzuling Cheng, Juan A. Segura, Francisco J. Alonso, Rui Curi, Alison Colquhoun, Ralph J. DeBerardinis, Javier Márquez, José M. Matés
Publikováno v:
Journal of Biomedical Science, Vol 28, Iss 1, Pp 1-16 (2021)
Abstract Background Glutaminase isoenzymes GLS and GLS2 play apparently opposing roles in cancer: GLS acts as an oncoprotein, while GLS2 (GAB isoform) has context specific tumour suppressive activity. Some microRNAs (miRNAs) have been implicated in p
Externí odkaz:
https://doaj.org/article/54b7f02e9af54421a8347e16e5f83924
Autor:
Daniela Mendes dos Reis Riccardi, Rodrigo Xavier das Neves, Emidio Marques de Matos-Neto, Rodolfo Gonzalez Camargo, Joanna Darck Carola Correia Lima, Katrin Radloff, Michele Joana Alves, Raquel Galvão Figuerêdo Costa, Flávio Tokeshi, José Pinhata Otoch, Linda Ferreira Maximiano, Paulo Sérgio Martins de Alcantara, Alison Colquhoun, Alessandro Laviano, Marilia Seelaender
Publikováno v:
Frontiers in Nutrition, Vol 7 (2020)
Cancer cachexia affects about 80% of advanced cancer patients, it is linked to poor prognosis and to date, there is no efficient treatment or cure. The syndrome leads to progressive involuntary loss of muscle and fat mass induced by systemic inflamma
Externí odkaz:
https://doaj.org/article/dfee8af5a526445eb3163f8566b39ced
Publikováno v:
Clinics, Vol 73, Iss suppl 1 (2018)
Eicosanoids are 20-carbon bioactive lipids derived from the metabolism of polyunsaturated fatty acids, which can modulate various biological processes including cell proliferation, adhesion and migration, angiogenesis, vascular permeability and infla
Externí odkaz:
https://doaj.org/article/5900f7aa67c64d969027bcea1a25e934
Autor:
Renato Ramos Massaro, Carla Abdo Brohem, Rebeca Leite de Almeida, Diogo Pineda Rivelli, Juliano Andreoli Miyake, Alison Colquhoun, Silvia Berlanga de Moraes Barros, Silvya Stuchi Maria-Engler
Publikováno v:
Brazilian Journal of Pharmaceutical Sciences, Vol 53, Iss 3 (2018)
ABSTRACT Gliomas account for the majority of primary malignant brain tumors and present invasive behavior into adjacent healthy tissue. While 4-NC had previously shown to induce apoptotic cell death in a melanoma model, for the glioma model described
Externí odkaz:
https://doaj.org/article/5d95aeb96ef64640ac3d3851a6b91b7b
Autor:
Christiane B. de Araujo, Andrea S. Heimann, Ricardo A. Remer, Lilian C. Russo, Alison Colquhoun, Fábio L. Forti, Emer S. Ferro
Publikováno v:
Biomolecules, Vol 9, Iss 4, p 150 (2019)
Intracellular peptides are produced by proteasomes following degradation of nuclear, cytosolic, and mitochondrial proteins, and can be further processed by additional peptidases generating a larger pool of peptides within cells. Thousands of intracel
Externí odkaz:
https://doaj.org/article/d3ce3ad7d3864fa293cfb66a60311681
Autor:
Hiviny de Ataides Raquel, Gustavo Masson, Sany Martins Pérego, Alison Colquhoun, Leonardo Jensen, Lisete C Michelini
Publikováno v:
Circulation. 144
Introduction: Besides intense renin-angiotensin system activation and sympathoexcitation, heart failure (HF) is accompanied by marked autonomic dysfunction. We showed previously in hypertensive rats that blood-brain barrier (BBB) dysfunction in preau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bce1378afd9d6bcd5158618898325a1
https://doi.org/10.1161/circ.144.suppl_1.13626
https://doi.org/10.1161/circ.144.suppl_1.13626
Publikováno v:
Hypertension. 78
Introduction: Besides intense neuro-hormonal activation, hypertension is accompanied by blood-brain barrier (BBB) dysfunction within preautonomic areas and marked autonomic imbalance. We showed previously that exercise training (T) corrected both inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca0943550503e22474dacb9bc38d8ec1
https://doi.org/10.1161/hyp.78.suppl_1.32
https://doi.org/10.1161/hyp.78.suppl_1.32
Autor:
Alison Colquhoun, Bárbara Fornaciari, Denise de Oliveira Silva, Samara Rodrigues Alves, Rodrigo Luis Silva Ribeiro Santos
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Diruthenium(II,III) metal-metal multiply bonded paddlewheel complexes bearing non-steroidal anti-inflammatory drugs are promising anticancer metallodrugs. The [Ru2(Ibp)4Cl] (Ibp, ibuprofenate anion from HIbp ibuprofen drug), free or encapsulated, sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b514428d241530ea7a835da2bbb14134
https://pubmed.ncbi.nlm.nih.gov/34601164
https://pubmed.ncbi.nlm.nih.gov/34601164