Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alison Brack"'
Autor:
Connor Johnson, Lisa N. Kretsge, William W. Yen, Balaji Sriram, Alexandra O’Connor, Ruichen Sky Liu, Jessica C. Jimenez, Rhushikesh A. Phadke, Kelly K. Wingfield, Charlotte Yeung, Tushare J. Jinadasa, Thanh P. H. Nguyen, Eun Seon Cho, Erelle Fuchs, Eli D. Spevack, Berta Escude Velasco, Frances S. Hausmann, Luke A. Fournier, Alison Brack, Sarah Melzer, Alberto Cruz-Martín
Publikováno v:
Molecular psychiatry. 27(5)
A hallmark of the anterior cingulate cortex (ACC) is its functional heterogeneity. Functional and imaging studies revealed its importance in the encoding of anxiety-related and social stimuli, but it is unknown how microcircuits within the ACC encode
Autor:
Vinay K. Kartha, Lindsay M. LaFave, Alison Brack, Yan Hu, Ya-Chieh Hsu, Caleb A. Lareau, Travis Law, Jiarui Ding, Aviv Regev, Zachary Chiang, Sai Ma, Andrew S. Earl, Tristan Tay, Jason D. Buenrostro, Bing Zhang
Publikováno v:
Cell
PMC
PMC
© 2020 Elsevier Inc. Cell differentiation and function are regulated across multiple layers of gene regulation, including modulation of gene expression by changes in chromatin accessibility. However, differentiation is an asynchronous process preclu
Autor:
Lindsay M. LaFave, Travis Law, Yan Hu, Aviv Regev, Bing Zhang, Vinay K. Kartha, Sai Ma, Ya-Chieh Hsu, Zachary Chiang, Alison Brack, Jiarui Ding, Jason D. Buenrostro, Caleb A. Lareau
SummaryCell differentiation and function are regulated across multiple layers of gene regulation, including the modulation of gene expression by changes in chromatin accessibility. However, differentiation is an asynchronous process precluding a temp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b51c8faf7fd28a55a65905250eeb2d44
https://doi.org/10.1101/2020.06.17.156943
https://doi.org/10.1101/2020.06.17.156943
Autor:
Lindsay M. LaFave, Kevin Meli, Tyler Jacks, Zachary Chiang, Jason D. Buenrostro, Annalisa Okimoto, Fabiana M. Duarte, Peter M. K. Westcott, Aviv Regev, Caleb A. Lareau, Alison Brack, Vinay K. Kartha, Sai Ma, Santiago Naranjo, Haley Hauck, Travis Law, Venkat Sankar, Isabella Del Priore
Publikováno v:
PMC
Regulatory networks that maintain functional, differentiated cell states are often dysregulated in tumor development. Here, we use single-cell epigenomics to profile chromatin state transitions in a mouse model of lung adenocarcinoma (LUAD). We ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09834a7bed67d28152c608f2c4a15859
https://hdl.handle.net/1721.1/133249
https://hdl.handle.net/1721.1/133249
Autor:
Jacob C. Ulirsch, Alison Brack, Elena Christian, Lauren H. Li, Jonathan H. Chen, Travis Law, Genevieve M. Boland, Karin Pelka, Leif S. Ludwig, Will Ge, Christopher Rodman, Yaara Oren, Orit Rozenblatt-Rosen, Jason D. Buenrostro, Martin J. Aryee, Vijay G. Sankaran, Christoph Muus, Nir Hacohen, Caleb A. Lareau, Aviv Regev
Publikováno v:
PMC
Lineage tracing provides key insights into the fate of individual cells in complex organisms. Although effective genetic labeling approaches are available in model systems, in humans, most approaches require detection of nuclear somatic mutations, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602b87e8e185fd2360bfd59bd792e3fc
https://hdl.handle.net/1721.1/125306
https://hdl.handle.net/1721.1/125306
Autor:
Zachary Chiang, Kevin Meli, Caleb A. Lareau, Travis Law, Venkat Sanker, Alison Brack, Vinay K. Kartha, Jason D. Buenrostro, Sai Ma, Lindsay M. LaFave, Isabella Del Priore, Aviv Regev, Santiago Naranjo, Tyler Jacks, Peter M. K. Westcott
Publikováno v:
Cancer Research. 80:PR08-PR08
A hallmark of cancer development is the loss of cellular identity due to the dysregulation of regulatory networks that maintain functional, differentiated states. Chromatin state has been linked to this control of cellular identity and developmental