Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alison Boyers"'
Autor:
Rik G.H. Lindeboom, Kaylee B. Worlock, Lisa M. Dratva, Masahiro Yoshida, David Scobie, Helen R. Wagstaffe, Laura Richardson, Anna Wilbrey-Clark, Josephine L. Barnes, Krzysztof Polanski, Jessica Allen-Hyttinen, Puja Mehta, Dinithi Sumanaweera, Jacqueline Boccacino, Waradon Sungnak, Ni Huang, Lira Mamanova, Rakesh Kapuge, Liam Bolt, Elena Prigmore, Ben Killingley, Mariya Kalinova, Maria Mayer, Alison Boyers, Alex Mann, Vitor Teixeira, Sam M. Janes, Rachel C. Chambers, Muzlifah Haniffa, Andrew Catchpole, Robert Heyderman, Mahdad Noursadeghi, Benny Chain, Andreas Mayer, Kerstin B. Meyer, Christopher Chiu, Marko Z. Nikolić, Sarah A. Teichmann
The COVID-19 pandemic is an ongoing global health threat, yet our understanding of the cellular disease dynamics remains limited. In our unique COVID-19 human challenge study we used single cell genomics of nasopharyngeal swabs and blood to temporall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d220950228bcc70a9b7e6d3734f32b9f
https://doi.org/10.1101/2023.04.13.23288227
https://doi.org/10.1101/2023.04.13.23288227
Autor:
Ben Killingley, Alex Mann, Mariya Kalinova, Alison Boyers, Niluka Goonawardane, Jie Zhou, Kate Lindsell, Samanjit S. Hare, Jonathan Brown, Rebecca Frise, Emma Smith, Claire Hopkins, Nicolas Noulin, Brandon Londt, Tom Wilkinson, Stephen Harden, Helen McShane, Mark Baillet, Anthony Gilbert, Michael Jacobs, Christine Charman, Priya Mande, Jonathan S. Nguyen-Van-Tam, Malcolm G. Semple, Robert C. Read, Neil M. Ferguson, Peter J. Openshaw, Garth Rapeport, Wendy S. Barclay, Andrew P. Catchpole, Christopher Chiu
To establish a novel SARS-CoV-2 human challenge model, 36 volunteers aged 18-29 years without evidence of previous infection or vaccination were inoculated with 10 TCID50 of a wild-type virus (SARS-CoV-2/human/GBR/484861/2020) intranasally. Two parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4acff7b7df2c4e91fd494a0e42410910
https://doi.org/10.21203/rs.3.rs-1121993/v1
https://doi.org/10.21203/rs.3.rs-1121993/v1
Autor:
Ben Killingley, Alex J. Mann, Mariya Kalinova, Alison Boyers, Niluka Goonawardane, Jie Zhou, Kate Lindsell, Samanjit S. Hare, Jonathan Brown, Rebecca Frise, Emma Smith, Claire Hopkins, Nicolas Noulin, Brandon Löndt, Tom Wilkinson, Stephen Harden, Helen McShane, Mark Baillet, Anthony Gilbert, Michael Jacobs, Christine Charman, Priya Mande, Jonathan S. Nguyen-Van-Tam, Malcolm G. Semple, Robert C. Read, Neil M. Ferguson, Peter J. Openshaw, Garth Rapeport, Wendy S. Barclay, Andrew P. Catchpole, Christopher Chiu
Publikováno v:
NATURE MEDICINE
Since its emergence in 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused hundreds of millions of cases and continues to circulate globally. To establish a novel SARS-CoV-2 human challenge model that enables controlled inve
Autor:
Fatima Addan, Andrew Catchpole, Daryl W. Borley, Carl Laxton, Elaine Thomas, Alison Boyers, Erica Bringas, Rob Lambkin-Williams, Brian Alton, Mariam Garelnabi, Geraldine Kelly, Nicolas Noulin, Edward J. Murray, Kieran Dee
Publikováno v:
Journal of Virological Methods. 224:83-90
Retroscreen (hVIVO) have developed an RSV human viral challenge model (hVCM) for testing the efficacy of novel antiviral therapies by monitoring changes in viral load and symptoms. The integrated cycler technology and Simplexa™ kits (Focus Diagnost
Autor:
Bart Remmerie, John P. DeVincenzo, Young-In Kim, Dirk Roymans, Rene Verloes, Nacer Lounis, Sarah Rusch, Anil Koul, Marita Stevens, Alison Boyers, Lisa Harrison, Elizabeth A. Meals, Juin Fok-Seang, Dymphy Huntjens, Kris Mari N
Publikováno v:
The Journal of infectious diseases. 218(5)
Background Respiratory syncytial virus (RSV) disease has no effective treatment. JNJ-53718678 is a fusion inhibitor with selective activity against RSV. Methods After confirmation of RSV infection or 5 days after inoculation with RSV, participants (n
Autor:
Alison Boyers, Samuel Israel, Juin Fok-Seang, Sarah Rusch, John P. DeVincenzo, Rene Verloes, Kris Mariёn, Dymphy Huntjens, Marita Stevens, Nacer Lounis
Publikováno v:
Open Forum Infectious Diseases. 3
Autor:
Stephen J. Streatfield, Christine E. Farrance, Vidadi Yusibov, Gene A. Palmer, Robert Lambkin, Konstantin Musiychuk, Natalia Ugulava, Yoko Shoji, Michael Russell, Geoffrey C. Schild, John S. Oxford, Alison Boyers, Shailaja Rabindran, Vadim Mett, Alex Mann, April Horsey, Patricia de la Rosa, Hong Bi
Publikováno v:
Influenza and Other Respiratory Viruses
Background Influenza A viruses are of major concern for public health, causing worldwide epidemics associated with high morbidity and mortality. Vaccines are critical for protection against influenza, but given the recent emergence of new strains wit
Autor:
Rob Lambkin-Williams, John S. Oxford, Jan Willem van der Laan, Alex Mann, Alison Boyers, Carla Herberts
Publikováno v:
Expert review of vaccines. 7(6)
The threat of a pandemic outbreak of influenza A H5N1 and H2N2 has brought attention to the development of new vaccines. Regulatory authorities require companies to provide data proving the effectiveness of vaccines, which cannot, however, be based o