Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Alison B. Shupp"'
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-30 (2019)
Abstract Introduction In a cancer-free environment in the adult, the skeleton continuously undergoes remodeling. Bone-resorbing osteoclasts excavate erosion cavities, and bone-depositing osteoblasts synthesize osteoid matrix that forms new bone, with
Externí odkaz:
https://doaj.org/article/bd65e56acfd14d24beac4740baf0a992
Autor:
Karen M. Bussard, Jonathan R. Brody, Gang Ning, Lebaron C. Agostini, Manish Neupane, Alison B. Shupp
Supplemental Table 1. Antibodies used for immunofluorescence Supplemental Table 2. Antibodies used for western blotting Supplemental Figure 1: EO-MCF7 sEVs decrease MCF7 proliferation. Supplemental Figure 2: Primary EO sEVs regulate MDA-MB-231 S-phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63cd35ba7596b9517388dda9c1c10ffc
https://doi.org/10.1158/1541-7786.22527006
https://doi.org/10.1158/1541-7786.22527006
Autor:
Karen M. Bussard, Jonathan R. Brody, Gang Ning, Lebaron C. Agostini, Manish Neupane, Alison B. Shupp
Bone is a common site of cancer metastasis, including cancers such as breast, prostate, and multiple myeloma. Disseminated tumor cells (DTC) shed from a primary tumor may travel to bone and can survive undetected for years before proliferating to for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11457c1781993ac518c4e8aaef1bfa26
https://doi.org/10.1158/1541-7786.c.6545289.v1
https://doi.org/10.1158/1541-7786.c.6545289.v1
Autor:
Avinoam Nevler, Aditi Jain, Jonathan R. Brody, Alison B. Shupp, Karen M. Bussard, Charles J. Yeo, Lebaron C. Agostini, Grace A. McCarthy
Publikováno v:
Mol Cancer Res
The DNA damage response (DDR) pathway sets the stage for tumorigenesis and provides both an opportunity for drug efficacy and resistance. Therapeutic approaches to target the DDR pathway include aiming to increase the efficacy of cytotoxic chemothera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0fe815ebb160bad6f5d8d7887f42c9
https://doi.org/10.1158/1541-7786.mcr-20-0708
https://doi.org/10.1158/1541-7786.mcr-20-0708
Publikováno v:
Curr Osteoporos Rep
PURPOSE OF REVIEW: In this review, we describe the biology of extracellular vesicles (EV) and how they contribute to bone-associated cancers. RECENT FINDINGS: Crosstalk between tumor and bone have been demonstrated to promote tumor and metastatic pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8db7895c5ab19ec00d591ded107f39be
https://pubmed.ncbi.nlm.nih.gov/33638774
https://pubmed.ncbi.nlm.nih.gov/33638774
Autor:
Alison B. Shupp, Gang Ning, Karen M. Bussard, Lebaron C. Agostini, Manish Neupane, Jonathan R. Brody
Publikováno v:
Mol Cancer Res
Bone is a common site of cancer metastasis, including cancers such as breast, prostate, and multiple myeloma. Disseminated tumor cells (DTC) shed from a primary tumor may travel to bone and can survive undetected for years before proliferating to for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032b14990d95be6920edd5ae9441bf3b
https://pubmed.ncbi.nlm.nih.gov/34021072
https://pubmed.ncbi.nlm.nih.gov/34021072
Publikováno v:
Advances in experimental medicine and biology. 1225
Many cancers commonly metastasize to bone. After entering the bone, cancer cells can interact with surrounding stromal cells, which ultimately influences metastasis progression. Extracellular vesicles, direct cell contact and gap junctions, and cytok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e57f0df6ea098a975de5f705dce083cf
https://pubmed.ncbi.nlm.nih.gov/32030644
https://pubmed.ncbi.nlm.nih.gov/32030644
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030357269
Many cancers commonly metastasize to bone. After entering the bone, cancer cells can interact with surrounding stromal cells, which ultimately influences metastasis progression. Extracellular vesicles, direct cell contact and gap junctions, and cytok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c017af572a4eb3f22ac181a2e42651ba
https://doi.org/10.1007/978-3-030-35727-6_1
https://doi.org/10.1007/978-3-030-35727-6_1
Publikováno v:
Cancer Research. 79:GS1-03
BrCa preferentially metastasizes to bone, where the 5-year relative survival rate is In a cancer-free environment in the adult, the skeleton continuously undergoes remodeling. Osteoclasts excavate erosion cavities and osteoblasts (OB) synthesize bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85bacc636cb6f344211b4ba29844f713
https://doi.org/10.1158/1538-7445.sabcs18-gs1-03
https://doi.org/10.1158/1538-7445.sabcs18-gs1-03
Autor:
Bernadette M. Adair, Cecilia Zemanek, Gail L. Matters, Andrea M. Mastro, Alison B. Shupp, Christopher M. Gigliotti, Christopher O. McGovern, Zi Kui Liu, Karen M. Bussard, Welley Siu Loc, Jenna M. Snyder, Nicholas T. Gigliotti, Zachary R. Wilczynski, James H. Adair, Kacey D Meisel
Publikováno v:
Nanomedicine
Calcium phosphosilicate nanoparticles (CPSNPs) are bioresorbable nanoparticles that can be bioconjugated with targeting molecules and encapsulate active agents -and deliver them to tumor cells without causing damage to adjacent healthy tissue. Data o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc8a70aaad70cc314c6042f7894fbc2
https://doi.org/10.1016/j.nano.2021.102383
https://doi.org/10.1016/j.nano.2021.102383