Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alison Almeda"'
Autor:
Ho Jung An, Mira A. Partha, HoJoon Lee, Billy T. Lau, Dmitri S. Pavlichin, Alison Almeda, Anna C. Hooker, Giwon Shin, Hanlee P. Ji
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
BackgroundColon microbiome composition contributes to the pathogenesis of colorectal cancer (CRC) and prognosis. We analyzed 16S rRNA sequencing data from tumor samples of patients with metastatic CRC and determined the clinical implications.Material
Externí odkaz:
https://doaj.org/article/f36916f7469247408cf94f0de232d4f5
Autor:
Billy T. Lau, Alison Almeda, Marie Schauer, Madeline McNamara, Xiangqi Bai, Qingxi Meng, Mira Partha, Susan M. Grimes, HoJoon Lee, Gregory M. Heestand, Hanlee P. Ji
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Epigenetic characterization of cell-free DNA (cfDNA) is an emerging approach for detecting and characterizing diseases such as cancer. We developed a strategy using nanopore-based single-molecule sequencing to measure cfDNA methylomes. This
Externí odkaz:
https://doaj.org/article/e323638932ce446b90aecb9fb1f4e521
Autor:
Billy T. Lau, Dmitri Pavlichin, Anna C. Hooker, Alison Almeda, Giwon Shin, Jiamin Chen, Malaya K. Sahoo, Chun Hong Huang, Benjamin A. Pinsky, Ho Joon Lee, Hanlee P. Ji
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-23 (2021)
Abstract Background The genome of SARS-CoV-2 is susceptible to mutations during viral replication due to the errors generated by RNA-dependent RNA polymerases. These mutations enable the SARS-CoV-2 to evolve into new strains. Viral quasispecies emerg
Externí odkaz:
https://doaj.org/article/6c281c23b3f34308a56ed35fdc580c16
Autor:
Hanlee P. Ji, Lan Zhao, Susan M. Grimes, Stephanie U. Greer, Carlos Suárez, Erik S. Hopmans, Alison Almeda, GiWon Shin, Hojoon Lee, Laura Miotke, Sigurdis Haraldsdottir
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-18 (2021)
Genome Medicine
Genome Medicine
Colorectal carcinomas (CRCs) which have lost DNA mismatch repair display hypermutability evident in a molecular phenotype called microsatellite instability (MSI). These mismatch repair deficient tumors are thought to lack widespread genomic instabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b68d90ab0c2a44b6b7ab53ee66ed201
https://doaj.org/article/f712076aec7c479ebafdae1d3b8bdf16
https://doaj.org/article/f712076aec7c479ebafdae1d3b8bdf16
Autor:
Billy T. Lau, Alison Almeda, Marie Schauer, Madeline McNamara, Xiangqi Bai, Qingxi Meng, Mira Partha, Susan M. Grimes, HoJoon Lee, Gregory M. Heestand, Hanlee P. Ji
Epigenetic characterization of cell-free DNA (cfDNA) is an emerging approach for characterizing diseases. We developed a strategy using nanopore-based single-molecule sequencing to measure cfDNA methylomes. This approach generated up to hundreds of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d7dae798589701532a70675e216a0cd
https://doi.org/10.1101/2022.06.22.497080
https://doi.org/10.1101/2022.06.22.497080
Autor:
Benjamin A. Pinsky, GiWon Shin, Hojoon Lee, Jiamin Chen, Hanlee P. Ji, Alison Almeda, Anna C Hooker, Dmitri S. Pavlichin, Billy T. Lau, Malaya K. Sahoo, ChunHong Huang
Publikováno v:
Genome Medicine
Genome Medicine, Vol 13, Iss 1, Pp 1-23 (2021)
medRxiv
article-version (status) pre
article-version (number) 1
Genome Medicine, Vol 13, Iss 1, Pp 1-23 (2021)
medRxiv
article-version (status) pre
article-version (number) 1
Background The genome of SARS-CoV-2 is susceptible to mutations during viral replication due to the errors generated by RNA-dependent RNA polymerases. These mutations enable the SARS-CoV-2 to evolve into new strains. Viral quasispecies emerge from de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c0ac6d2da8a6a51de2bf257f637b5b
https://doi.org/10.1101/2020.11.02.20224816
https://doi.org/10.1101/2020.11.02.20224816
Autor:
Lincoln Nadauld, Bryce Moulton, Hanlee P. Ji, Gregory M. Heestand, Derrick S. Haslem, Alison Almeda, Christina Wood-Bouwens, Hojoon Lee
Publikováno v:
J Mol Diagn
As a high-performance solution for longitudinal monitoring of patients being treated for metastatic cancer, a single-color digital PCR (dPCR) assay that detects and quantifies specific cancer mutations present in circulating tumor DNA (ctDNA) was dev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36f8856ea13cd7dcded3be2d680be912
https://pubmed.ncbi.nlm.nih.gov/31837432
https://pubmed.ncbi.nlm.nih.gov/31837432
Autor:
Maya M. Arce, Christina Wood-Bouwens, Derrick Haslem, Billy T. Lau, John Bell, Alison Almeda, Matt Kubit, Bryce Moulton, Robin Romero, Robert P. St. Onge, Lincoln Nadauld, Hanlee P. Ji
Publikováno v:
Cancer Research. 79:2278-2278
Single color digital PCR (sc-dPCR) is a robust approach for the quantitation of low allelic fraction mutations in clinical oncology samples. More recently this technology has been employed to identify mutations from circulating tumor DNA (ctDNA) that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78b9f629be55f35fb2691f6319e42bf1
https://doi.org/10.1158/1538-7445.am2019-2278
https://doi.org/10.1158/1538-7445.am2019-2278
Autor:
George A. Poultsides, Alison Almeda, Susan M. Grimes, Christina Wood-Bouwens, Hanlee P. Ji, Jiamin Chen, Billy T. Lau, Anuja Sathe
Publikováno v:
Cancer Research. 78:2126-2126
Colorectal cancer (CRC) metastasizes to the liver in over half of patients. Compared to primary tumors, the biology of CRC liver metastasis (CLM) is poorly characterized. We performed high-throughput microfluidics-based single-cell RNA sequencing (sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65c0d1e161c81d4cdaf6215c205748f9
https://doi.org/10.1158/1538-7445.am2018-2126
https://doi.org/10.1158/1538-7445.am2018-2126