Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Alison A Weiss"'
Autor:
David L Lentz, Trinity L Hamilton, Stephanie A Meyers, Nicholas P Dunning, Kathryn Reese-Taylor, Armando Anaya Hernández, Debra S Walker, Eric J Tepe, Atasta Flores Esquivel, Alison A Weiss
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301497 (2024)
For millennia, healing and psychoactive plants have been part of the medicinal and ceremonial fabric of elaborate rituals and everyday religious practices throughout Mesoamerica. Despite the essential nature of these ritual practices to the societal
Externí odkaz:
https://doaj.org/article/c0079af4461b42f3808b2adf8628a721
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178966 (2017)
Infection with Shiga toxin (Stx) producing Escherichia coli O157:H7 can cause the potentially fatal complication hemolytic uremic syndrome, and currently only supportive therapy is available. Lack of suitable animal models has hindered study of this
Externí odkaz:
https://doaj.org/article/90a99e622f5b4436bfa5d54f16846579
Autor:
Scott H Millen, Mineo Watanabe, Eiji Komatsu, Fuminori Yamaguchi, Yuki Nagasawa, Eri Suzuki, Haleigh Monaco, Alison A Weiss
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137379 (2015)
Whooping cough due to Bordetella pertussis is increasing in incidence, in part due to accumulation of mutations which increase bacterial fitness in highly vaccinated populations. Polymorphisms in the pertussis toxin, ptxA and ptxB genes, and the pert
Externí odkaz:
https://doaj.org/article/5f70d7c6b9df4185b218db0195eebd19
Autor:
Sayali S Karve, Alison A Weiss
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101173 (2014)
The major virulence factor of Shiga toxin producing E. coli, is Shiga toxin (Stx), an AB5 toxin that consists of a ribosomal RNA-cleaving A-subunit surrounded by a pentamer of receptor-binding B subunits. The two major isoforms, Stx1 and Stx2, and St
Externí odkaz:
https://doaj.org/article/c67abc5ab8a44c75b4f5517df2b2dbe0
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72885 (2013)
Pertussis toxin (PTx) is the major virulence factor of Bordetella pertussis. The enzymatic or active (A) subunit inactivates host G protein coupled receptor (GPCR) signaling pathways. The non-enzymatic binding (B) subunit also mediates biological eff
Externí odkaz:
https://doaj.org/article/b0678150cbd5464d9d65afe0e59e236c
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69823 (2013)
Shiga toxin (Stx), the main virulence factor of Shiga toxin producing Escherichia coli, is a major public health threat, causing hemorrhagic colitis and hemolytic uremic syndrome. Currently, there are no approved therapeutics for these infections; ho
Externí odkaz:
https://doaj.org/article/127dbd64d95b40e298ae264af5e97040
Autor:
Karen M Gallegos, Deborah G Conrady, Sayali S Karve, Thusitha S Gunasekera, Andrew B Herr, Alison A Weiss
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30368 (2012)
Immunologically distinct forms of Shiga toxin (Stx1 and Stx2) display different potencies and disease outcomes, likely due to differences in host cell binding. The glycolipid globotriaosylceramide (Gb3) has been reported to be the receptor for both t
Externí odkaz:
https://doaj.org/article/bce1d863753b4a97bfb6f6be11328253
Autor:
Deborah G Conrady, Michael J Flagler, David R Friedmann, Bradley D Vander Wielen, Rhett A Kovall, Alison A Weiss, Andrew B Herr
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15153 (2010)
Escherichia coli strain O157:H7 is a major cause of food poisoning that can result in severe diarrhea and, in some cases, renal failure. The pathogenesis of E. coli O157:H7 is in large part due to the production of Shiga toxin (Stx), an AB(5) toxin t
Externí odkaz:
https://doaj.org/article/1489be60df354a77a8c9bf5200b213af
Autor:
Alison R Weiss, William A Liguore, Kristin Brandon, Xiaojie Wang, Zheng Liu, Jacqueline S Domire, Dana Button, Sathya Srinivasan, Christopher D Kroenke, Jodi L McBride
Publikováno v:
eLife, Vol 11 (2022)
We created a new nonhuman primate model of the genetic neurodegenerative disorder Huntington’s disease (HD) by injecting a mixture of recombinant adeno-associated viral vectors, serotypes AAV2 and AAV2.retro, each expressing a fragment of human mut
Externí odkaz:
https://doaj.org/article/40c54a4ae76146b79b16dfb2a213c0f2
Autor:
David L. Lentz, Trinity L. Hamilton, Nicholas P. Dunning, Eric J. Tepe, Vernon L. Scarborough, Stephanie A. Meyers, Liwy Grazioso, Alison A. Weiss
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Tikal, a major city of the ancient Maya world, has been the focus of archaeological research for over a century, yet the interactions between the Maya and the surrounding Neotropical forests remain largely enigmatic. This study aimed to help
Externí odkaz:
https://doaj.org/article/b4d219b7d3764d61808077b11f9df018