Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Alison A McBride"'
Autor:
Alix Warburton, Catherine J Redmond, Katharine E Dooley, Haiqing Fu, Maura L Gillison, Keiko Akagi, David E Symer, Mirit I Aladjem, Alison A McBride
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007179 (2018)
Integration of human papillomavirus (HPV) genomes into cellular chromatin is common in HPV-associated cancers. Integration is random, and each site is unique depending on how and where the virus integrates. We recently showed that tandemly integrated
Externí odkaz:
https://doaj.org/article/2c5f67a370b1458995c9eda5e1cf579d
Publikováno v:
PLoS Pathogens, Vol 13, Iss 10, p e1006660 (2017)
We have shown previously that Sp100 (a component of the ND10 nuclear body) represses transcription, replication and establishment of incoming human papillomavirus (HPV) DNA in the early stages of infection. In this follow up study, we show that Sp100
Externí odkaz:
https://doaj.org/article/00daadd512f7485a81a4b2a5601b0d4e
Autor:
Alison A McBride, Alix Warburton
Publikováno v:
PLoS Pathogens, Vol 13, Iss 4, p e1006211 (2017)
Externí odkaz:
https://doaj.org/article/d1ae1c196fe94cfeb68a118a1774ae75
Autor:
Ehren Dancy, Pamela Stratton, Dominique C. Pichard, Beatriz E. Marciano, Edward W. Cowen, Alison A. McBride, Koenraad Van Doorslaer, Melissa A. Merideth, Noemi Salmeri, Marybeth S. Hughes, Theo Heller, Mark Parta, Dennis D. Hickstein, Heidi H. Kong, Steven M. Holland, Christa S. Zerbe
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectivePatients with pathogenic variants in the GATA Binding Protein 2 (GATA2), a hematopoietic transcription factor, are at risk for human papillomavirus-related (HPV) anogenital cancer at younger than expected ages. A female cohort with GATA2 hap
Externí odkaz:
https://doaj.org/article/d6962edf636b4e08a6feb288037c400d
Autor:
Christopher B Buck, Koenraad Van Doorslaer, Alberto Peretti, Eileen M Geoghegan, Michael J Tisza, Ping An, Joshua P Katz, James M Pipas, Alison A McBride, Alvin C Camus, Alexa J McDermott, Jennifer A Dill, Eric Delwart, Terry F F Ng, Kata Farkas, Charlotte Austin, Simona Kraberger, William Davison, Diana V Pastrana, Arvind Varsani
Publikováno v:
PLoS Pathogens, Vol 12, Iss 4, p e1005574 (2016)
Polyomaviruses are a family of DNA tumor viruses that are known to infect mammals and birds. To investigate the deeper evolutionary history of the family, we used a combination of viral metagenomics, bioinformatics, and structural modeling approaches
Externí odkaz:
https://doaj.org/article/7739ad4591ff4b3b9ba8b0164dfb5663
Publikováno v:
PLoS Pathogens, Vol 10, Iss 5, p e1004117 (2014)
It has long been recognized that oncogenic viruses often integrate close to common fragile sites. The papillomavirus E2 protein, in complex with BRD4, tethers the viral genome to host chromatin to ensure persistent replication. Here, we map these tar
Externí odkaz:
https://doaj.org/article/4709a3d6b4d54500995303b904cc3250
Autor:
Nozomi Sakakibara, Dan Chen, Moon Kyoo Jang, Dong Wook Kang, Hans F Luecke, Shwu-Yuan Wu, Cheng-Ming Chiang, Alison A McBride
Publikováno v:
PLoS Pathogens, Vol 9, Iss 11, p e1003777 (2013)
Replication foci are generated by many viruses to concentrate and localize viral DNA synthesis to specific regions of the cell. Expression of the HPV16 E1 and E2 replication proteins in keratinocytes results in nuclear foci that recruit proteins asso
Externí odkaz:
https://doaj.org/article/f1f42fcc361c416d93cb41d7500e2c55
Publikováno v:
PLoS Pathogens, Vol 9, Iss 7, p e1003321 (2013)
Externí odkaz:
https://doaj.org/article/1ca6b0f26e45476ebf7c57ff388306f6
Autor:
Alison A. McBride, Elizabeth A. White
Publikováno v:
Cancer Discovery. 13:814-816
Summary: Human papillomavirus (HPV)–positive cancer cells contain virus and host DNA and exhibit marked genome instability. In this issue of Cancer Discovery, Akagi and colleagues characterize the remarkably complex landscape of virus–host DNA mo
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-15 (2021)
NPJ Genomic Medicine
NPJ Genomic Medicine
Oncogenic human papillomavirus (HPV) genomes are often integrated into host chromosomes in HPV-associated cancers. HPV genomes are integrated either as a single copy, or as tandem repeats of viral DNA interspersed with, or without, host DNA. Integrat