Electrogenic sodium bicarbonate cotransporter NBCe1 regulates pancreatic β cell function in type 2 diabetes

Autor: Michael F. Romero, Y. S. Prakash, Satish Sen, Gary E. Shull, Matthew R. Brown, Alison A. Stiller, Aleksey V. Matveyenko, Heather L. Holmes, Naureen Javeed, Kuntol Rakshit, Tracy K. Her

Publikováno v: J Clin Invest

Pancreatic β cell failure in type 2 diabetes mellitus (T2DM) is attributed to perturbations of the β cell’s transcriptional landscape resulting in impaired glucose-stimulated insulin secretion. Recent studies identified SLC4A4 (a gene encoding an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623cb5ac371912498eaf1c803d9f5b61
https://doi.org/10.1172/jci142365

Use of 3D Robotic Ultrasound for In Vivo Analysis of Mouse Kidneys

Autor: Christopher J. Moore, Adriana Gregory, Jordan D. Miller, Alison A. Stiller, Heather L. Holmes, Carolyn M Roos, Ryan C. Gesser, Tomasz J. Czernuszewicz, Timothy L. Kline, Michael F. Romero

Publikováno v: Journal of Visualized Experiments.

Common modalities for in vivo imaging of rodents include positron emission tomography (PET), computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound (US). Each method has limitations and advantages, including availability, ease of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::753c91fbe80257b75226744868ac4c2e
https://doi.org/10.3791/62682-v

Robotic Ultrasound and Novel Collagen Analyses for Polycystic Kidney Disease Research Using Mice.

Autor: Sussman CR; Nephrology and Hypertension, Mayo Clinic College of Medicine and Science, Rochester, Minnesota., Holmes HL; Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science, Rochester, Minnesota., Stiller A; Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science, Rochester, Minnesota., Thao K; Nephrology and Hypertension, Mayo Clinic College of Medicine and Science, Rochester, Minnesota., Gregory AV; Radiology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota., Anaam D; Radiology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota., Meloche R; Nephrology and Hypertension, Mayo Clinic College of Medicine and Science, Rochester, Minnesota., Mkhaimer Y; Nephrology and Hypertension, Mayo Clinic College of Medicine and Science, Rochester, Minnesota., Wells HH; Nephrology and Hypertension, Mayo Clinic College of Medicine and Science, Rochester, Minnesota., Vasconcelos LD; Radiology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota., Urban MW; Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.; Radiology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota., Macura SI; Nephrology and Hypertension, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.; Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota., Harris PC; Nephrology and Hypertension, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.; Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota., Kline TL; Nephrology and Hypertension, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.; Radiology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota., Romero MF; Nephrology and Hypertension, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.; Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.

Publikováno v: Kidney360 [Kidney360] 2024 Oct 01; Vol. 5 (10), pp. 1543-1552. Date of Electronic Publication: 2024 Aug 12.