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pro vyhledávání: '"Alison, Howard"'
Publikováno v:
Biomedicines, Vol 9, Iss 12, p 1770 (2021)
Studies have highlighted the relevance of extracellular glycine and serine in supporting high growth rates of rapidly proliferating tumours. The present study analysed the role of the specific glycine transporter GLYT1 in supplying glycine to cancer
Externí odkaz:
https://doaj.org/article/8292786da11f416eab650dedf6948b0d
Publikováno v:
Biomedicines, Vol 9, Iss 1770, p 1770 (2021)
Biomedicines; Volume 9; Issue 12; Pages: 1770
Biomedicines
Biomedicines; Volume 9; Issue 12; Pages: 1770
Biomedicines
Studies have highlighted the relevance of extracellular glycine and serine in supporting high growth rates of rapidly proliferating tumours. The present study analysed the role of the specific glycine transporter GLYT1 in supplying glycine to cancer
Autor:
Susannah Eves, Carol E. Harris, Alison Howard, Christopher Burgess, Oliver T. Dale, Cheng Han, Rupali T. Shah, Stuart Winter, Penny L. White
Publikováno v:
The Laryngoscope. 125:1637-1643
Objectives/Hypothesis As survival rates in oropharyngeal cancer improve, long-term functional outcomes are increasingly important to understand. We report long-term functional outcomes in a cohort of surviving patients with oropharyngeal squamous cel
Publikováno v:
Molecular and Cellular Biology
We previously identified the ZTRE (zinc transcriptional regulatory element) in genes involved in zinc homeostasis and showed that it mediates transcriptional repression in response to zinc. We now report that ZNF658 acts at the ZTRE. ZNF658 was ident
Autor:
Barry H. Hirst, Alison Howard, Wendy D. Smith, C.L. Townes, Judith Hall, Emily L. Abbot, Stephanie Bell, Janet A. Wilson
Publikováno v:
Molecular Oral Microbiology. 27:160-171
Host defence peptides (HDP), including the defensins and hCAP-18, function as part of the innate immune defences, protecting the host epithelia from microbial attachment and invasion. Recurrent acute tonsillitis (RAT), in which patients suffer repeat
Publikováno v:
The Journal of Physiology. 588:995-1009
Glycine protects mammalian intestine against oxidative damage caused by ischaemia-reperfusion (IR) injury and prevents or reverses experimentally-induced colitis. However the mechanism of protection remains largely unknown. The objectives of the curr
Autor:
Alison Howard, Vadivel Ganapathy, Julian R.F. Walters, Catriona M.H. Anderson, David T. Thwaites
Publikováno v:
The Journal of Physiology. 587:731-744
Taurine is an essential amino acid in some mammals and is conditionally essential in humans. Taurine is an abundant component of meat and fish-based foods and has been used as an oral supplement in the treatment of disorders such as cystic fibrosis a
Publikováno v:
The Journal of Nutrition. 134:2957-2964
Intestinal function depends on the presence of luminal nutrients and is altered during starvation and refeeding. Amino acids are essential for enterocytes, but the luminal supply is compromised with changes in dietary intake. To test the hypothesis t