Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Alisha N. Jones"'
Autor:
Alisha N. Jones, André Mourão, Anna Czarna, Alex Matsuda, Roberto Fino, Krzysztof Pyrc, Michael Sattler, Grzegorz M. Popowicz
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The replication complex (RC) of SARS-CoV-2 was recently shown to be one of the fastest RNA-dependent RNA polymerases of any known coronavirus. With this rapid elongation, the RC is more prone to incorporate mismatches during elongation, resu
Externí odkaz:
https://doaj.org/article/02bfc4b9af0e44b6a67b247f314fe0c8
Autor:
Hamed Kooshapur, Nila Roy Choudhury, Bernd Simon, Max Mühlbauer, Alexander Jussupow, Noemi Fernandez, Alisha N. Jones, Andre Dallmann, Frank Gabel, Carlo Camilloni, Gracjan Michlewski, Javier F. Caceres, Michael Sattler
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
hnRNP A1 is an auxiliary factor that promotes the Microprocessor-mediated processing of pri-mir-18a, of the oncomiR-1 cluster. Here the authors employ an integrative structural biology approach and provide insights into the molecular mechanism of how
Externí odkaz:
https://doaj.org/article/014a6dc8990b44dca7c25370f4266456
Publikováno v:
Nucleic Acids Research. 50:2350-2362
The A-repeat region of the lncRNA Xist is critical for X inactivation and harbors several N6-methyladenosine (m6A) modifications. How the m6A modification affects the conformation of the conserved AUCG tetraloop hairpin of the A-repeats and how it ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2e98d1ab6bb4bdd70a2793e8b1e95b
https://doi.org/10.1093/nar/gkac080
https://doi.org/10.1093/nar/gkac080
Autor:
Daniel Krappmann, Isabel Meininger, Alisha N Jones, Carina Graß, Kathi Zarnack, Michael Sattler, Melina Klostermann, Arie Geerlof
Publikováno v:
Science Advances. 8
Alternative splicing is controlled by differential binding of trans-acting RNA binding proteins (RBPs) to cis-regulatory elements in intronic and exonic pre-mRNA regions 1-3. How secondary structure in the pre-mRNA transcripts affects recognition by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0f597945967a137ff8905a23aeb8b1
https://doi.org/10.1126/sciadv.abp9153
https://doi.org/10.1126/sciadv.abp9153
Autor:
Alisha N, Jones, Carina, Graß, Isabel, Meininger, Arie, Geerlof, Melina, Klostermann, Kathi, Zarnack, Daniel, Krappmann, Michael, Sattler
Publikováno v:
Science advances. 8(31)
Alternative splicing plays key roles for cell type-specific regulation of protein function. It is controlled by cis-regulatory RNA elements that are recognized by RNA binding proteins (RBPs). The MALT1 paracaspase is a key factor of signaling pathway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7d26ae21a8545f65df8ede7c7147a783
https://pubmed.ncbi.nlm.nih.gov/35921415
https://pubmed.ncbi.nlm.nih.gov/35921415
The A-repeat region of the lncRNA Xist is required for X-chromosome inactivation in placental mammals and comprises 8.5 copies of a conserved 24-nucleotide motif separated by uracil-rich linkers. Several experimentally-supported secondary structures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23df74e5ebec78d2fd06ad451d93abe4
https://doi.org/10.1101/2022.07.26.501616
https://doi.org/10.1101/2022.07.26.501616
Autor:
Alex Matsuda, Jacek Plewka, Yuliya Chykunova, Alisha N. Jones, Magdalena Pachota, Michał Rawski, André Mourão, Abdulkarim Karim, Leanid Kresik, Kinga Lis, Igor Minia, Kinga Hartman, Ravi Sonani, Grzegorz Dubin, Michael Sattler, Piotr Suder, Paweł Mak, Grzegorz M. Popowicz, Krzysztof Pyrć, Anna Czarna
Coronaviruses protect their single-stranded RNA genome with a methylated cap during replication. The capping process is initiated by several nonstructural proteins (nsp) encoded in the viral genome. The methylation is performed by two methyltransfera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::108a19ae0c214f4af9f4d60d96f27cb8
https://doi.org/10.1101/2022.01.25.477673
https://doi.org/10.1101/2022.01.25.477673
Publikováno v:
J. Mol. Biol. 434:167705 (2022)
MicroRNAs (miRNAs) are small, noncoding RNAs that mediate post-transcriptional downregulation of specific target genes. These transcripts are the products of a two-step processing pathway; primary miRNAs (pri-miRNAs) are processed by Drosha into indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f120ebc7a079979fba43d6aac610cd7
https://doi.org/10.1016/j.jmb.2022.167705
https://doi.org/10.1016/j.jmb.2022.167705
Autor:
Michael Sattler, Alisha N Jones
Publikováno v:
Journal of Molecular Cell Biology
Following the discovery of numerous long non-coding RNA (lncRNA) transcripts in the human genome, their important roles in biology and human disease are emerging. Recent progress in experimental methods has enabled the identification of structural fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41139a6078b78e1da55be8fa6183a14b
https://doi.org/10.1093/jmcb/mjz086
https://doi.org/10.1093/jmcb/mjz086
Autor:
Benjamin Busch, Veit Hornung, Gesine Behrens, Matthias von Gamm, Wolfgang Wurst, Arie Geerlof, Johannes Lichti, Regina Feederle, Annalisa Schaub, Dhruv Chauhan, Elke Glasmacher, Katharina Essig, Annette Feuchtinger, Alisha N Jones, Christine Wolf, Andreas Ehrlich, Caroline C. Friedel, Kathrin Davari, Vigo Heissmeyer, Michael Sattler, Matthias H. Tschöp, Mathias Heikenwalder, Joachim Pircher, Anna Macht, Christian Schulz, Stefanie M. Hauck
Publikováno v:
J. Exp. Med. 216, 1700-1723 (2019)
The Journal of Experimental Medicine
Journal of experimental medicine 216(7), 1700-1723 (2019). doi:10.1084/jem.20181762
The Journal of Experimental Medicine
Journal of experimental medicine 216(7), 1700-1723 (2019). doi:10.1084/jem.20181762
von Gamm et al. demonstrate that mice deficient for the RNase Regnase-3 (Zc3h12c) develop hypertrophic lymph nodes and a systemic interferon response. Regnase-3 is a functional RNase that acts in myeloid cells upon IRF signaling, suggesting it to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6ae2c005f84820cba549cbfe6e849d
https://doi.org/10.1084/jem.20181762
https://doi.org/10.1084/jem.20181762