Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alisha M. Block"'
Autor:
Alisha M. Block, Sarah B. Namugenyi, Nagendra P. Palani, Alyssa M. Brokaw, Leanne Zhang, Kenneth B. Beckman, Anna D. Tischler
Publikováno v:
mSystems, Vol 8, Iss 1 (2023)
ABSTRACT Tolerance of Mycobacterium tuberculosis to antibiotics contributes to the long duration of tuberculosis (TB) treatment and the emergence of drug-resistant strains. M. tuberculosis drug tolerance is induced by nutrient restriction, but the ge
Externí odkaz:
https://doaj.org/article/2f31e4cb07c9427ebfe2941bb20dceee
Autor:
Natalie M. Kirk, Qinfeng Huang, Sophia Vrba, Mizanur Rahman, Alisha M. Block, Hannah Murphy, Dylan W. White, Sarah B. Namugenyi, Hinh Ly, Anna D. Tischler, Yuying Liang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) remains a major global health threat. The only available vaccine Bacille Calmette-Guérin (BCG) does not prevent adult pulmonary TB. New effective TB vaccines should aim to stim
Externí odkaz:
https://doaj.org/article/fc54f3337c324bcbbed618a067e3197a
Transposon sequencing reveals metabolic pathways essential for Mycobacterium tuberculosis infection.
Publikováno v:
PLoS Pathogens, Vol 20, Iss 3, p e1011663 (2024)
New drugs are needed to shorten and simplify treatment of tuberculosis caused by Mycobacterium tuberculosis. Metabolic pathways that M. tuberculosis requires for growth or survival during infection represent potential targets for anti-tubercular drug
Externí odkaz:
https://doaj.org/article/f267152da8b34104840fea9aa47d2245
Autor:
Shubhangi Agarwal, Melanie Bernt, Alisha M. Block, Paul D’Alvise, Jens Pfannstiel, Julia Steuber, Hannes Kurz, Charlotte Toulouse, Martin Hasselmann, Claudia C. Häse, Günter Fritz
Publikováno v:
J Bacteriol
The Na+ ion-translocating NADH:quinone oxidoreductase (NQR) from Vibrio cholerae is a membrane-bound respiratory enzyme which harbors flavins and Fe-S clusters as redox centers. The NQR is the main producer of the sodium motive force (SMF) and drives