Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alisha Kellner"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The A chains of ADP-ribosylating toxins exploit Hsp90 for translocation into the host cytosol. Here, we hypothesize that cis proline residues play a key role in toxin recognition by Hsp90. Our model is largely derived from studies on the unusual inte
Externí odkaz:
https://doaj.org/article/30783fd7411e4a99a9f2c72235eaa0b1
Autor:
Michelle D. Cherne, Jesse Hall, Alisha Kellner, Christine F. Chong, Amy L. Cole, Alexander M. Cole
Publikováno v:
Viruses, Vol 11, Iss 5, p 408 (2019)
While extensive research efforts have decreased human immunodeficiency virus (HIV) transmissions and mortalities, new challenges have arisen in the fight to eradicate HIV. Drug resistance to antiretroviral therapy threatens infected individuals, whil
Externí odkaz:
https://doaj.org/article/37440cca46534ed2b4dcdbcfb9b70edf
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology
The A chains of ADP-ribosylating toxins exploit Hsp90 for translocation into the host cytosol. Here, we hypothesize that cis proline residues play a key role in toxin recognition by Hsp90. Our model is largely derived from studies on the unusual inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8393d64a29a262602092d39f4314e3
https://doi.org/10.3389/fcimb.2021.771653
https://doi.org/10.3389/fcimb.2021.771653
Publikováno v:
J Biol Chem
Cholera toxin (CT) travels by vesicle carriers from the cell surface to the endoplasmic reticulum (ER) where the catalytic A1 subunit of CT (CTA1) dissociates from the rest of the toxin, unfolds, and moves through a membrane-spanning translocon pore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::916f6ec55f8c00bc8a409d89698dbe57
https://europepmc.org/articles/PMC6690686/
https://europepmc.org/articles/PMC6690686/
Publikováno v:
Cell Microbiol
Cholera toxin (Ctx) is an AB-type protein toxin that acts as an adenosine diphosphate (ADP)-ribosyltransferase to disrupt intracellular signalling in the target cell. It moves by vesicle carriers from the cell surface to the endoplasmic reticulum (ER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f44f69ff52ae3e6c966576d7e5bac3
https://pubmed.ncbi.nlm.nih.gov/31231933
https://pubmed.ncbi.nlm.nih.gov/31231933
Autor:
Alisha Kellner, Alexander M. Cole, Christine F. Chong, Michelle D. Cherne, Jesse Hall, Amy L. Cole
Publikováno v:
Viruses, Vol 11, Iss 5, p 408 (2019)
Viruses
Volume 11
Issue 5
Viruses
Volume 11
Issue 5
While extensive research efforts have decreased human immunodeficiency virus (HIV) transmissions and mortalities, new challenges have arisen in the fight to eradicate HIV. Drug resistance to antiretroviral therapy threatens infected individuals, whil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ddcb4217c025dbba8c3c768cca68632
https://www.mdpi.com/1999-4915/11/5/408
https://www.mdpi.com/1999-4915/11/5/408
Autor:
Alisha Kellner, Ken Teter
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14f37fd41435e86c931fb496442b63e8
https://doi.org/10.1096/fasebj.2019.33.1_supplement.780.4
https://doi.org/10.1096/fasebj.2019.33.1_supplement.780.4