Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Alisha K. Holloway"'
Publikováno v:
PLoS Genetics, Vol 3, Iss 10, Pp 2007-2013 (2007)
Detailed studies of individual genes have shown that gene expression divergence often results from adaptive evolution of regulatory sequence. Genome-wide analyses, however, have yet to unite patterns of gene expression with polymorphism and divergenc
Externí odkaz:
https://doaj.org/article/4b184b9602e54bb891eec3356c3bb92b
Autor:
Pui-Yan Kwok, Elio Schijlen, James W. Hicks, Katherine S. Pollard, Marie Altmanová, Alex I. Makunin, Tomaso Patarnello, Petr Velenský, Michail Rovatsos, Yulia Mostovoy, Alisha K. Holloway, Vladimir A. Trifonov, Valerio Orlandini, Yvonne Y. Y. Lai, Marco Fondi, Massimo Milan, Ivan Rehák, Renato Fani, I. G. Kichigin, Lukáš Kratochvíl, Benoit G. Bruneau, Alessio Iannucci, Claudio Ciofi, Martina Johnson Pokorná, Tim S. Jessop, Oliver A. Ryder, Walter L. Eckalbar, Angel C.Y. Mak, Abigail L. Lind, Joseph R. Mendelson
Publikováno v:
Nature ecology & evolution, vol 3, iss 8
Nature ecology & evolution
Nature Ecology and Evolution 3 (2019) 8
Nature Ecology and Evolution, 3(8), 1241-1252
Nature ecology & evolution
Nature Ecology and Evolution 3 (2019) 8
Nature Ecology and Evolution, 3(8), 1241-1252
Monitor lizards are unique among ectothermic reptiles in that they have high aerobic capacity and distinctive cardiovascular physiology resembling that of endothermic mammals. Here, we sequence the genome of the Komodo dragon Varanus komodoensis, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd9768187f3dbbc526728997db02150
https://doi.org/10.1038/s41559-019-0945-8
https://doi.org/10.1038/s41559-019-0945-8
Autor:
Sean Thomas, Jason G Underwood, Elizabeth Tseng, Alisha K Holloway, Bench To Basinet CvDC Informatics Subcommittee
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94650 (2014)
The chicken has long served as an important model organism in many fields, and continues to aid our understanding of animal development. Functional genomics studies aimed at probing the mechanisms that regulate development require high-quality genome
Externí odkaz:
https://doaj.org/article/2f77c3f4edd449909126db718484fb76
Developmental Loci Harbor Clusters of Accelerated Regions That Evolved Independently in Ape Lineages
Publikováno v:
Molecular Biology and Evolution
Some of the fastest evolving regions of the human genome are conserved noncoding elements with many human-specific DNA substitutions. These human accelerated regions (HARs) are enriched nearby regulatory genes, and several HARs function as developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc2ad89eff4267ededa83f52ae8e364
https://doi.org/10.1093/molbev/msy109
https://doi.org/10.1093/molbev/msy109
Publikováno v:
PLoS Genetics, Vol 7, Iss 4, p e1002053 (2011)
Transcription factor binding site(s) (TFBS) gain and loss (i.e., turnover) is a well-documented feature of cis-regulatory module (CRM) evolution, yet little attention has been paid to the evolutionary force(s) driving this turnover process. The predo
Externí odkaz:
https://doaj.org/article/4022592c8fb54f9684852fea022fee9f
Autor:
Nelle Lambert, Marie-Alexandra Lambot, Angéline Bilheu, Valérie Albert, Yvon Englert, Frédérick Libert, Jean-Christophe Noel, Christos Sotiriou, Alisha K Holloway, Katherine S Pollard, Vincent Detours, Pierre Vanderhaeghen
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17753 (2011)
The developmental mechanisms through which the cerebral cortex increased in size and complexity during primate evolution are essentially unknown. To uncover genetic networks active in the developing cerebral cortex, we combined three-dimensional reco
Externí odkaz:
https://doaj.org/article/7cdcf5f2429e4c4c9a68b416acfe883a
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e24717 (2011)
The molecular basis and characteristics of familial non-medullary thyroid cancer are poorly understood. In this study, we performed microRNA (miRNA) profiling of familial and sporadic papillary thyroid cancer tumor samples.Genome wide miRNA profiling
Externí odkaz:
https://doaj.org/article/b304fab50bd04f6da7a066750ea99c7f
Autor:
David J Begun, Alisha K Holloway, Kristian Stevens, Ladeana W Hillier, Yu-Ping Poh, Matthew W Hahn, Phillip M Nista, Corbin D Jones, Andrew D Kern, Colin N Dewey, Lior Pachter, Eugene Myers, Charles H Langley
Publikováno v:
PLoS Biology, Vol 5, Iss 11, p e310 (2007)
The population genetic perspective is that the processes shaping genomic variation can be revealed only through simultaneous investigation of sequence polymorphism and divergence within and between closely related species. Here we present a populatio
Externí odkaz:
https://doaj.org/article/6b804cd42a204968b1a74d54a4da1c4d
Autor:
Alisha K Holloway, David J Begun
Publikováno v:
PLoS ONE, Vol 2, Iss 10, p e1113 (2007)
Adaptive protein evolution is pervasive in Drosophila. Genomic studies, thus far, have analyzed each protein as a single entity. However, the targets of adaptive events may be localized to particular parts of proteins, such as protein domains or regi
Externí odkaz:
https://doaj.org/article/2aac0537815a423ba9911680ffc64739
Autor:
Orlandini, BG Bruneau, Lukáš Kratochvíl, Abigail L. Lind, Mendelson, Tomaso Patarnello, Alessio Iannucci, Martina Johnson Pokorná, A. Trifonov, Elio Schijlen, Tim S. Jessop, James W. Hicks, Michail Rovatsos, Yulia Mostovoy, Alisha K. Holloway, Angel C.Y. Mak, Renato Fani, Oliver A. Ryder, Alex I. Makunin, Marco Fondi, Massimo Milan, Marie Altmanová, Lai Yy, Walter L. Eckalbar, Pui-Yan Kwok, Claudio Ciofi, Katherine S. Pollard, I. G. Kichigin
SummaryMonitor lizards are unique among ectothermic reptiles in that they have a high aerobic capacity and distinctive cardiovascular physiology which resembles that of endothermic mammals. We have sequenced the genome of the Komodo dragon (Varanus k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0195ff889ea80186b9855dc8702bd18f
https://doi.org/10.1101/551978
https://doi.org/10.1101/551978
