Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Alisha Chitrakar"'
Autor:
Marta Sanz, Ann Marie K. Weideman, Adam R. Ward, Matthew L. Clohosey, Susana Garcia-Recio, Sara R. Selitsky, Brendan T. Mann, Marie Anne Iannone, Chloe P. Whitworth, Alisha Chitrakar, Carolina Garrido, Jennifer Kirchherr, Alisha R. Coffey, Yi- Hsuan Tsai, Shahryar Samir, Yinyan Xu, Dennis Copertino, Alberto Bosque, Brad R. Jones, Joel S. Parker, Michael G. Hudgens, Nilu Goonetilleke, Natalia Soriano-Sarabia
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Antiretroviral therapy (ART) is not curative due to the existence of cellular reservoirs of latent HIV-1 that persist during therapy. Current research efforts to cure HIV-1 infection include “shock and kill” strategies to disrupt latency using sm
Externí odkaz:
https://doaj.org/article/88374e57932242c08c418283c9d5a0d0
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is a complex disease which immune response can be more or less potent. In severe cases, patients might experience a cytokine storm
Externí odkaz:
https://doaj.org/article/3d43aea077d143598412aef32e868dff
Publikováno v:
Cells, Vol 11, Iss 22, p 3572 (2022)
Gamma/delta (γδ) T cells are innate-like immune effectors that are a critical component linking innate and adaptive immune responses. They are recognized for their contribution to tumor surveillance and fight against infectious diseases. γδ T cel
Externí odkaz:
https://doaj.org/article/680efab5cb0740eaa393b2818c090def
Autor:
Michael A. Estrella, Jin Du, Li Chen, Sneha Rath, Eliza Prangley, Alisha Chitrakar, Tsutomu Aoki, Paul Schedl, Joshua Rabinowitz, Alexei Korennykh
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nocturnin is a rhythmically expressed protein that regulates metabolism under the control of circadian clock proposed to function through the deadenylation of metabolic enzyme mRNAs. Here the authors show that Nocturnin and its fly homolog Curled cat
Externí odkaz:
https://doaj.org/article/91822378ee9c4553912dbca3ceb0472b
Publikováno v:
Pathogens, Vol 11, Iss 6, p 611 (2022)
The use of antiretroviral therapy (ART) for Human Immunodeficiency Virus (HIV) treatment has been highly successful in controlling plasma viremia to undetectable levels. However, a complete cure for HIV is hindered by the presence of replication-comp
Externí odkaz:
https://doaj.org/article/c8467434dc3e484aa4f387a7efbde2fb
Publikováno v:
Cell Stem Cell
Reprogramming of H3K9me3-dependent heterochromatin is required for early development. How H3K9me3 is involved in early human development remains, however, largely unclear. Here, we resolve the temporal landscape of H3K9me3 during human preimplantatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b5901836a77a7c0e0120fa74bd21564
https://europepmc.org/articles/PMC9484580/
https://europepmc.org/articles/PMC9484580/
Autor:
Rosemary L. Pope, Alisha Chitrakar, Prakash Sah, Tyler Shadid, Jimmy D. Ballard, Lauren A. Zenewicz
Publikováno v:
Infect Immun
Group 3 innate lymphocytes (ILC3s) are rare immune cells localized in mucosal tissues, especially the gastrointestinal (GI) tract. Despite their rarity, they are a major source of the cytokine interleukin-22 (IL-22), which protects the GI epithelium
Publikováno v:
J Immunol
Von Hippel–Lindau (VHL) is an E3 ubiquitin ligase that targets proteins, including HIF-1α, for proteasomal degradation. VHL and HIF regulate the balance between glycolysis and oxidative phosphorylation, which is critical in highly dynamic T cells.
Autor:
Susan R. Weiss, Sneha Rath, Sergei V. Kotenko, Kaitlin Demarest, Ned S. Wingreen, Alisha Chitrakar, Alexei Korennykh, Jesse Donovan, Raghavendra Rao Sridhar, Yize Li
Publikováno v:
Proceedings of the National Academy of Sciences
Cells of all mammals recognize double-stranded RNA (dsRNA) as a foreign material. In response, they release interferons (IFNs) and activate a ubiquitously expressed pseudokinase/endoribonuclease RNase L. RNase L executes regulated RNA decay and halts
Autor:
Alisha Chitrakar, Micaela L. Montgomery, Grzegorz B. Gmyrek, Daniel J.J. Carr, Adrian Filiberti, Derek J. Royer
Publikováno v:
J Virol
The contribution of T cell and antibody responses following vaccination in resistance to herpes simplex virus 1 (HSV-1) infection continues to be rigorously investigated. In the present article, we explore the contribution of CD8(+) T cells specific