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Autor:
Robert W. Moon, Barbara Clough, Nathalie Bouloc, Jonathan M. Large, Judith L. Green, Simon A. Osborne, David Whalley, Hayley M. Jones, Anthony A. Holder, Keith H. Ansell, Timothy M. Chapman, Kristian Birchall, Claire Wallace, Emmanuel C. Patin, Ela Smiljanic-Hurley, Alisdair Hearn, Debra L. Taylor
Publikováno v:
Antimicrobial Agents and Chemotherapy
PfCDPK1 is a Plasmodium falciparum calcium-dependent protein kinase, which has been identified as a potential target for novel antimalarial chemotherapeutics. In order to further investigate the role of PfCDPK1, we established a high-throughput in vi