Comparing the levels of CTLA-4-dependent biological defects in patients with LRBA deficiency and CTLA-4 insufficiency

Autor: Mehmet C. Catak, Bengu Akcam, Sevgi Bilgic Eltan, Royala Babayeva, Ibrahim S. Karakus, Gamze Akgun, Dilek Baser, Alper Bulutoglu, Feyza Bayram, Nurhan Kasap, Ayca Kiykim, Gonca Hancioglu, Sefika I. Kokcu Karadag, Yasemin kendir Demirkol, Selime Ozen, Sukru Cekic, Dilek Ozcan, Neslihan Edeer Karaca, Ayse S. Sasihuseyinoglu, Murat Cansever, Esra Ozek Yucel, Zeynep Tamay, Derya U. Altintas, Cigdem Aydogmus, Fatih Celmeli, Haluk Cokugras, Nesrin Gulez, Ferah Genel, Ayse Metin, Sukru N. Guner, Necil Kutukculer, Sevgi Keles, Ismail Reisli, Sara S. Kilic, Alisan Yildiran, Elif Karakoc‐Aydiner, Bernice Lo, Ahmet Ozen, Safa Baris

© 2022 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.Background: Lipopolysaccharide-responsive beige-like anchor protein (LRBA) deficiency and cytotoxic T-lymphocyte protein-4 (CTLA-4) insufficiency are recently described d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d0b7664b5951635514430e6e5152d4
https://hdl.handle.net/11424/289151

An examination of the relationship between regulatory T cells and symptom flare-ups in children and adolescents diagnosed with chronic tic disorder and Tourette syndrome

Autor: Zeynep Yildirim, Koray Karabekiroglu, Bekir B. Artukoglu, Zehra Babadağı, Saliha Baykal, Alisan Yildiran, Mehmet Halil Çeliksoy, James F. Leckman

Publikováno v: Nordic Journal of Psychiatry. 75:18-24

Tourette syndrome (TS) is a childhood-onset neurodevelopmental disorder characterized by several motor and phonic tics.In this study, we aimed to compare activated regulatory T cell (Treg) values between patients with TS/chronic tic disorder (CTD) an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8667e9f48d86b142dadfe70e92f6b20f
https://doi.org/10.1080/08039488.2020.1779808

Impaired respiratory burst contributes to infections in PKC-deficient patients

Autor: Paul A. Brogan, Alexandre Belot, Tom Le Voyer, Jacinta Bustamante, Mélanie Migaud, Marion Roderick, Gulbu Uzel, Figen Dogu, Jean-Laurent Casanova, Anna Lena Neehus, Jamel El-Benna, Ahmet Ozen, Laurent Abel, Erdal Ince, Mohammad Shahrooei, Engin Altundag, Elif Karakoc-Aydiner, Gonca Hancioglu, Anne Puel, Aydan Ikinciogullari, Manon Roynard, Kunihiko Moriya, Kaan Boztug, Karim Dorgham, Romain Lévy, Kathrin Haake, Alisan Yildiran, Sule Haskologlu, Nico Lachmann, Safa Baris, Guy Gorochov, Nima Parvaneh, Alejandro Nieto-Patlán, Hassan Abolhassani, Ayca Kiykim

Publikováno v: Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2021, 218 (9), ⟨10.1084/jem.20210501⟩

Patients with autosomal recessive protein kinase C delta (PKC delta) deficiency suffer from childhood-onset autoimmunity, including systemic lupus erythematosus. They also suffer from recurrent infections that overlap with those seen in patients with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a0108981e5b97b2f91b4a2bd2dc906
https://hdl.handle.net/11424/243874

Single-Center Study of 72 Patients with Severe Combined Immunodeficiency: Clinical and Laboratory Features and Outcomes

Autor: Ozlem, Bayram, Sule, Haskologlu, Deniz, Bayrakoğlu, Sevgi Kostel, Bal, Candan, Islamoglu, Funda Erol, Cipe, Tanil, Kendirli, Nazmiye, Kursun, Sukru Nail, Guner, Alisan, Yildiran, Gunseli, Bozdogan, Mutlu, Yuksek, Ismail, Reisli, Klara, Dalva, Caner, Aytekin, Kaan, Boztug, Figen, Dogu, Aydan, Ikinciogullari

Publikováno v: Journal of clinical immunology. 41(7)

Severe combined immunodeficiency is an inborn error of immunity characterized by impairments in the numbers and functions of T and B lymphocytes due to various genetic causes, and if it remains untreated, patients succumb to infections during the fir

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a6092061c3933a5da717753e48aeaa06
https://pubmed.ncbi.nlm.nih.gov/34114123

Clinical Features and HSCT Outcome for SCID in Turkey

Autor: Atilla Halil Elhan, Ilhan Tezcan, Aydan Ikinciogullari, Savaş Kansoy, Gulsum Karasu, Orhan Gürsel, Sule Haskologlu, Vedat Uygun, Alphan Kupesiz, Figen Dogu, Deniz Cagdas, Can Ateş, Tuba Tugrul, Alisan Yildiran, Akif Yeşilipek, Serap Aksoylar

Publikováno v: Journal of clinical immunology. 39(3)

Elhan, Atilla Halil/0000-0003-3324-248X; Ikinciogullari, Aydan/0000-0003-1145-0843; Dogu, Figen/0000-0002-7869-4941; ates, can/0000-0003-2286-4398 WOS: 000468974100018 PubMed: 30924026 Severe combined immunodeficiency (SCID) is the most serious PID,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945f5aab2e2ec55937401736e71cde39
https://pubmed.ncbi.nlm.nih.gov/30924026