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of 4
pro vyhledávání: '"Alisabeth H. Shearn"'
Autor:
Colin T. Shearn, Kristofer S. Fritz, Alisabeth H. Shearn, Laura M. Saba, Kelly E. Mercer, Bridgette Engi, James J. Galligan, Piotr Zimniak, David J. Orlicky, Martin J. Ronis, Dennis R. Petersen
Publikováno v:
Redox Biology, Vol 7, Iss C, Pp 68-77 (2016)
Chronic alcohol consumption induces hepatic oxidative stress resulting in production of highly reactive electrophilic α/β-unsaturated aldehydes that have the potential to modify proteins. A primary mechanism of reactive aldehyde detoxification by h
Externí odkaz:
https://doaj.org/article/a0c8a20508814e5c97a8857b03dd80be
Autor:
Colin T. Shearn, Laura Saba, David J. Orlicky, James R. Roede, Alisabeth H. Shearn, Dennis R. Petersen
Publikováno v:
Free Radical Biology and Medicine. 113:280-290
In the liver, a contributing factor in the pathogenesis of non-alcoholic fatty liver disease is oxidative stress leading to the accumulation of highly reactive electrophilic α/β unsaturated aldehydes. The objective of this study was to determine if
Autor:
Alisabeth H. Shearn, David J. Orlicky, Bridgette Engi, Kelly E. Mercer, Dennis R. Petersen, Piotr Zimniak, Colin T. Shearn, James J. Galligan, Martin J. J. Ronis, Laura Saba, Kristofer S. Fritz
Publikováno v:
Redox Biology, Vol 7, Iss C, Pp 68-77 (2016)
Redox Biology
Redox Biology
Chronic alcohol consumption induces hepatic oxidative stress resulting in production of highly reactive electrophilic α/β-unsaturated aldehydes that have the potential to modify proteins. A primary mechanism of reactive aldehyde detoxification by h
Publikováno v:
Free radical biologymedicine. 89
Oxidative stress is a significant contributing factor in the pathogenesis of alcoholic liver disease (ALD). In the murine models of chronic alcohol consumption, induction of oxidative stress results in increased peroxidation of polyunsaturated fatty